Fragrant Angelica Root Extract
Also known as: Angelica sinensis (Oliv.) Diels, Dong Quai, Danggui, Angelica sinensis
Overview
*Angelica sinensis*, commonly known as Dong Quai or Danggui, is a perennial herb native to China, Japan, and Korea. The root of the plant is a staple in traditional Chinese medicine, valued for its purported ability to replenish blood, promote blood circulation, relieve pain, and moisten the intestines. It is frequently used to address menstrual disorders and menopausal symptoms. The root contains essential oils, such as ligustilides, and water-soluble compounds like ferulic acid, which are thought to contribute to its therapeutic effects. While some clinical trials suggest potential benefits, particularly when combined with other herbs, the overall quality of evidence remains variable, necessitating more rigorous research to confirm its efficacy and safety. It is available in various forms, including dried crude powder and fluid extracts.
Benefits
*Angelica sinensis* has shown potential benefits in specific areas, although the evidence is not always robust. A systematic review and meta-analysis indicated that a combination of *Angelica sinensis* and *Radix Astragali* improved pulmonary function in patients with idiopathic pulmonary fibrosis. Some evidence suggests it may help manage menopausal symptoms, though high-quality human studies are lacking. Animal and in vitro studies have also pointed to antioxidant, anti-inflammatory, and potential anticancer properties. The herb may be particularly beneficial for women experiencing menstrual disorders or menopausal symptoms. However, the effect sizes and clinical significance are not consistently quantified across studies, and the time course of benefits remains largely unestablished.
How it works
*Angelica sinensis* is believed to exert its effects through multiple biological pathways. Compounds like ligustilides and ferulic acid may contribute to improved blood circulation and anti-inflammatory actions. The herb primarily interacts with the circulatory and reproductive systems. While the precise molecular targets are not yet fully defined, its influence on blood circulation and potential anti-inflammatory properties are key aspects of its mechanism of action. Further research is needed to fully elucidate the absorption, bioavailability, and specific molecular interactions of *Angelica sinensis*.
Side effects
While generally considered safe when used appropriately, *Angelica sinensis* can cause side effects in some individuals. Common side effects include headaches. Less common side effects reported are increased blood pressure. Due to its potential effects on blood circulation, *Angelica sinensis* may interact with anticoagulants and blood thinners, increasing the risk of bleeding. It is contraindicated during pregnancy, lactation, and in cases of hemorrhage. Special populations, such as children and individuals with diarrhea, should avoid its use. It's important to monitor blood pressure and consult with a healthcare provider before use, especially for those with pre-existing health conditions or those taking medications.
Dosage
The appropriate dosage of *Angelica sinensis* varies depending on the intended use and individual factors. There is no well-established minimum effective dose or maximum safe dose. It is typically administered orally, often as a dried crude powder or fluid extract. Specific dosage recommendations should be obtained from a healthcare provider or based on traditional Chinese medicine guidelines. Due to limited data on absorption factors, it is important to follow recommended dosages carefully. As a general precaution, exceeding recommended dosages should be avoided, and consultation with a healthcare professional is advised to determine the most appropriate and safe dosage.
FAQs
Is *Angelica sinensis* safe to use during pregnancy?
No, *Angelica sinensis* is contraindicated during pregnancy due to potential risks. Consult a healthcare provider for safer alternatives.
Can *Angelica sinensis* interact with other medications?
Yes, it may interact with anticoagulants and blood thinners, increasing the risk of bleeding. Consult a healthcare provider if you are taking other medications.
What are the expected results from using *Angelica sinensis*?
Results vary depending on the condition being treated. It is not a proven treatment for cancer or other serious conditions in humans. Consult a healthcare provider for realistic expectations.
How should *Angelica sinensis* be administered?
Follow traditional Chinese medicine guidelines or consult a healthcare provider. Oral administration is common, often as a dried crude powder or fluid extract.
Are there any specific health conditions where *Angelica sinensis* should be avoided?
Yes, avoid use in cases of hemorrhage and in individuals with diarrhea. Monitor blood pressure and consult with a healthcare provider before use.
Research Sources
- https://pubmed.ncbi.nlm.nih.gov/32425767/ – This systematic review and meta-analysis investigated the effects of *Radix Astragali* and *Radix Angelicae Sinensis* on idiopathic pulmonary fibrosis. The study found that the combination of these herbs improved pulmonary function and exercise tolerance in patients with this condition, suggesting a potential therapeutic benefit.
- https://pubmed.ncbi.nlm.nih.gov/33359858/ – This ethnopharmacological study focused on *Angelica reflexa* and its anti-asthmatic effects. While not directly applicable to *A. sinensis*, it provides insights into the potential respiratory benefits of other Angelica species, highlighting the need for further research on *A. sinensis*.
- https://taylorandfrancis.com/knowledge/Medicine_and_healthcare/Clinical_nutrition/Angelica_sinensis/ – This review highlights the traditional uses of *A. sinensis* and its potential benefits for menopausal symptoms and antioxidant effects. It emphasizes the need for more high-quality human studies to confirm these benefits and fully understand the herb's mechanisms of action.
- https://www.healthline.com/nutrition/angelica-root – This article provides an overview of Angelica root, discussing its traditional uses and potential health benefits. It highlights the need for further research to confirm these benefits and fully understand the herb's mechanisms of action.
