ProveIt Supplements

Independent, evidence-based supplement analysis.

✓ Not Sponsored

✓ No Paid Reviews

✓ Science-Based

Company

  • About Us
  • Our Methodology
  • Contact
  • Blog
  • Authors

Legal

  • Privacy Policy
  • Terms of Service
  • Medical Disclaimer
  • Affiliate Disclosure

Resources

  • All Categories
  • Ingredient Database
  • Browse Supplements
  • FAQ

© 2025 ProveIt Supplements. All rights reserved.

Medical Disclaimer: The information provided is for educational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen.

Prove It
Browse SupplementsBlogAuthorsAboutMethodologyFAQ
Get Your Personalized Supplement StackSupplement Stack Quiz
Menu
HomeBrowse SupplementsBlogAuthorsAboutMethodologyFAQ
Back

Freeze Dried Bovine Spleen

Also known as: Bos taurus spleen, bovine spleen, Freeze-dried bovine spleen, Desiccated beef spleen, Bovine spleen powder, Beef Spleen

Overview

Freeze-dried bovine spleen is a dietary supplement derived from the spleen of cattle, processed to preserve its nutrient content. It is a natural source of heme iron, vitamin B12, selenium, and unique spleen peptides like tuftsin and splenopentin. The supplement is marketed for supporting immune function, iron status, and general wellness. Freeze-drying helps retain the nutrient profile and extends shelf life. While bovine spleen is rich in essential nutrients, clinical research on its specific effects as a supplement is limited. Most evidence is indirect, based on its nutrient composition and animal studies. It is available in freeze-dried, desiccated, and powdered forms.

Benefits

Bovine spleen is a rich source of heme iron, which is highly bioavailable and may support iron levels in individuals at risk of deficiency. It also provides vitamin B12 and selenium, essential for hematopoiesis and antioxidant defense. Spleen peptides like tuftsin and splenopentin may modulate immune function, although clinical evidence is lacking. While bovine spleen may benefit individuals with iron deficiency or those at risk of anemia, direct evidence from human studies is absent. The effect sizes and time course of benefits are not established in clinical trials.

How it works

Bovine spleen's benefits are primarily attributed to its nutrient content. Heme iron from the spleen is absorbed more efficiently than non-heme iron, supporting red blood cell production. Spleen peptides may interact with immune cells, potentially modulating immune function, although the exact mechanisms are not well-characterized in humans. The supplement primarily interacts with the hematopoietic system through iron and B12, and potentially with the immune system via spleen peptides. Heme iron absorption relies on transporters like DMT1 and ferroportin, while the molecular targets for spleen peptides on immune cells are theoretical.

Side effects

Bovine spleen supplementation is generally considered safe, based on the consumption patterns of organ meats. Clinical trials specifically examining bovine spleen supplementation have not reported any common, uncommon, or rare side effects. There are no known drug interactions associated with bovine spleen. However, caution is advised for individuals with iron overload disorders. The safety of bovine spleen supplementation has not been established in pregnant or breastfeeding women, or in children. More research is needed to fully assess the safety profile in these populations.

Dosage

Optimal dosage ranges for bovine spleen supplementation have not been established in clinical studies. Marketed products typically recommend a serving size of around 1,500 mg. There are no specific timing recommendations for taking bovine spleen. It is commonly available in freeze-dried, desiccated, or powdered forms. Heme iron absorption can be enhanced by consuming vitamin C concurrently and may be inhibited by calcium and phytates. Vitamin C may be considered a required cofactor to enhance iron absorption. The maximum safe dose of bovine spleen has not been determined.

FAQs

How should I store freeze-dried bovine spleen?

Freeze-dried bovine spleen is shelf-stable and does not require refrigeration, making it convenient for storage. Keep it in a cool, dry place away from direct sunlight to maintain its quality.

Is bovine spleen safe to take?

Bovine spleen is generally considered safe, but clinical data are limited. No adverse events have been reported in the available literature, but more research is needed to confirm its safety profile comprehensively.

When is the best time to take bovine spleen?

Bovine spleen can be taken with meals at any time of day. There are no specific timing requirements, but taking it with vitamin C may enhance iron absorption.

What are the expected benefits of taking bovine spleen?

Bovine spleen may support iron status and provide B vitamins. Any potential immune effects are theoretical and not yet proven by clinical studies. It is primarily a nutritional supplement.

Is bovine spleen a proven immune booster?

No, bovine spleen is not a proven immune booster. While it contains peptides that may modulate immune function, its primary benefits are nutritional, related to its iron and B vitamin content.

Research Sources

  • https://pubmed.ncbi.nlm.nih.gov/33507025/ – This study focuses on the use of freeze-dried plasma (FDP) in trauma patients, assessing its impact on coagulation and clinical outcomes. The research highlights the potential benefits of FDP in improving survival rates and reducing transfusion requirements in severe trauma cases. The study underscores the importance of early FDP administration in managing coagulopathy associated with trauma.
  • https://www.codeage.com/products/beef-spleen – This is a product page for Codeage's Beef Spleen supplement. It highlights the supplement's nutrient density, particularly its high concentration of heme iron and other essential nutrients. The page promotes the supplement for supporting overall health and well-being, emphasizing its traditional use as a source of vital nutrients.
  • https://www.tugawaycuwin.com/all-training-tugs/beef-spleen-freeze-dried-raw – This is a product page for freeze-dried beef spleen marketed as a dog treat. It emphasizes the natural and raw nature of the product, highlighting its nutritional benefits for dogs. The page promotes the product as a healthy and palatable option for canine training and rewards.
  • https://pubmed.ncbi.nlm.nih.gov/38721151 – This study investigates the impact of early nutritional support on clinical outcomes in critically ill patients. The research emphasizes the importance of providing adequate nutrition to improve patient recovery and reduce complications. The findings suggest that early nutritional interventions can significantly enhance the overall management of critically ill individuals.
  • https://nutriest.eu/products/grass-fed-desiccated-beef-spleen-supplement/ – This is a product page for Nutriest's grass-fed desiccated beef spleen supplement. It highlights the supplement's source from grass-fed cattle and its rich nutrient profile. The page promotes the supplement for supporting immune function, energy levels, and overall vitality, emphasizing its natural and high-quality ingredients.

Supplements Containing Freeze Dried Bovine Spleen

ORGAN COMPLEX SUPPLEMENT by 1st Ingredients
65

ORGAN COMPLEX SUPPLEMENT

1st Ingredients

Score: 65/100

Recommended Articles

Top Nutrients in Greens Powders: A Health Boost

Greens powders are a convenient way to supplement your diet with essential nutrients, offering a variety of health benefits.