Full Spectrum Hemp Extract
Also known as: Full Spectrum Hemp Extract, CBD-rich hemp extract, hemp oil
Overview
Full Spectrum Hemp Extract is a botanical supplement derived from *Cannabis sativa* cultivars grown for industrial purposes, characterized by low tetrahydrocannabinol (THC) content. It contains a broad spectrum of cannabinoids, including cannabidiol (CBD), cannabigerol (CBG), terpenes, and flavonoids. It is primarily used for its potential health benefits, such as reducing anxiety, inflammation, and improving sleep quality. The 'entourage effect' suggests that the combination of these compounds may enhance therapeutic effects. Research on Full Spectrum Hemp Extract is growing, but more rigorous clinical trials are needed to validate its therapeutic potential. Available evidence varies in quality, with some systematic reviews and meta-analyses, but many studies have methodological limitations, including small sample sizes and variability in extract composition. Full Spectrum Hemp Extract is available in various forms, including oils, capsules, and topicals.
Benefits
Full Spectrum Hemp Extract has shown potential benefits for anxiety and seizure reduction. Some studies suggest that CBD, a major component, may reduce anxiety in both human and animal models. CBD-rich extracts have also been shown to reduce seizure frequency in patients with refractory epilepsy, with approximately 64% of patients reporting improvement. Secondary benefits include potential improvements in sleep quality and inflammation, although the evidence is less robust. The effect size varies widely depending on the condition and study design. Benefits may be observed within hours for acute effects like anxiety reduction, while chronic benefits like seizure control may require weeks to months. It may be particularly beneficial for individuals with treatment-resistant epilepsy.
How it works
Full Spectrum Hemp Extract primarily interacts with the endocannabinoid system, influencing CB1 and CB2 receptors, although CBD itself has a low affinity for these receptors. It may also affect the nervous system, immune system, and potentially the cardiovascular system. CBD interacts with various receptors and channels, including TRPV1 and GPR55. The bioavailability of Full Spectrum Hemp Extract varies depending on the method of administration, with oral forms generally having lower bioavailability compared to sublingual or topical applications. This interaction with the endocannabinoid system and other biological pathways contributes to its potential therapeutic effects.
Side effects
Full Spectrum Hemp Extract is generally considered safe, though side effects can occur. Common side effects (occurring in >5% of users) include fatigue, changes in appetite, and diarrhea. Uncommon side effects (1-5%) include dizziness and nausea. Rare side effects (<1%) include severe allergic reactions. It may interact with certain medications, such as blood thinners and sedatives. It is contraindicated in pregnancy and breastfeeding due to limited data on safety. Caution is advised in children and individuals with liver disease. Due to potential drug interactions, it is crucial to consult with a healthcare provider before use, especially if taking other medications. Always start with a low dose to assess tolerance and monitor for any adverse effects.
Dosage
The minimum effective dose of Full Spectrum Hemp Extract varies by condition; for anxiety, doses as low as 25 mg of CBD may be effective. Optimal dosage ranges typically fall between 25 mg to 100 mg of CBD per day for most conditions. The maximum safe dose is not well established, but doses up to 1500 mg of CBD per day have been used in clinical trials without severe adverse effects. It may be taken sublingually for rapid onset or orally for sustained effects. Sublingual or topical forms may offer better bioavailability than oral capsules. Food intake can affect absorption; taking it with a meal may enhance bioavailability. There are no established required cofactors, but fatty meals may improve absorption.
FAQs
Is Full Spectrum Hemp Extract safe?
Generally safe, but consult a healthcare provider before use, especially if taking other medications. Monitor for potential side effects like fatigue or changes in appetite.
When should I take Full Spectrum Hemp Extract?
Can be taken at any time, but sublingual forms may be preferred for rapid effects. Consistency is key, so choose a time that fits your daily routine.
Will Full Spectrum Hemp Extract make me high?
No, it is not psychoactive due to low THC content, but may still interact with other medications. Ensure the product is THC-free or contains only trace amounts.
How long does it take to feel the effects?
May vary widely depending on the condition being treated and the method of administration. Sublingual application may provide faster relief than oral capsules.
Are there any drug interactions?
Yes, it may interact with certain medications, such as blood thinners and sedatives. Consult with a healthcare provider to avoid potential adverse effects.
Research Sources
- https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2017.00081/full – This systematic review and meta-analysis examined the effects of CBD on blood pressure, heart rate, and blood flow. The review included 25 studies, encompassing both human and animal models, with both acute and chronic study designs. The key finding was that CBD has variable effects on cardiovascular parameters, with some studies showing significant changes, but the study was limited by heterogeneity in study design and outcomes.
- https://www.frontiersin.org/journals/neurology/articles/10.3389/fneur.2018.00759/full – This study investigated the efficacy of CBD-rich extracts in reducing seizure frequency in patients with refractory epilepsy. The meta-analysis included 670 patients with treatment lengths ranging from 3 to 12 months. The key finding was that CBD-rich extracts showed higher efficacy in reducing seizure frequency compared to purified CBD, although the study was limited by mostly observational designs with variable extract compositions.
- https://jamanetwork.com/journals/jama/fullarticle/2338251 – This systematic review assessed the potential benefits of cannabinoids, including CBD, for various medical conditions. The review included various studies on cannabinoids for medical use, with varying durations. The key finding was that cannabinoids have potential benefits for several medical conditions, though evidence varies by condition, but the study was limited by clinical heterogeneity and limited randomized controlled trials.
- https://pubmed.ncbi.nlm.nih.gov/33614949/ – This study, a meta-analysis, investigated the efficacy of CBD for anxiety disorders. The study included both human and animal models. The key finding was that CBD has variable effects on anxiety, with some studies showing significant changes, but the study was limited by heterogeneity in study design and outcomes.
- https://www.mdpi.com/2218-273X/14/11/1434 – This review provides an overview of the therapeutic potential of cannabinoids. It highlights the potential benefits of cannabinoids, including CBD, for several medical conditions, though evidence varies by condition. The review emphasizes the need for more rigorous clinical trials to validate these findings.
Supplements Containing Full Spectrum Hemp Extract
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