Hmr Lignan
Also known as: 7-Hydroxymatairesinol, HMRlignan™, Potassium acetate complex of 7-Hydroxymatairesinol, HMRlignan
Overview
HMRlignan™ is a lignan derived from the knots of the Norway spruce (Picea abies) and primarily consists of 7-Hydroxymatairesinol. It is manufactured in Switzerland and has been FDA-approved since 2004. This dietary supplement is marketed for its potential health benefits, particularly its antitumor, antioxidant, and antifungal properties. Although existing research includes a mix of animal studies and a limited number of human trials, there is promising evidence regarding its safety and preliminary efficacy. HMRlignan™ may significantly impact overall health due to its bioactive properties, although further research is needed to fully understand its long-term effects, safety profile, and optimal dosing guidelines.
Benefits
HMRlignan™ is primarily associated with antitumor effects, supported by animal studies demonstrating tumor growth reduction at doses of 15 mg/kg. Evidence indicates it possesses strong antifungal activity against various fungi and antioxidant properties that may benefit general health. The compound is metabolized to enterolactone, which is linked to additional health benefits, possibly including further antitumor action. Safe consumption levels range from 72 to 144 mg per day, with studies suggesting significant health advantages at these doses. Overall, the evidence suggests potential improvements in immune response and cellular health, particularly for the general population.
How it works
HMRlignan™ exerts its action chiefly through its conversion to enterolactone, which is associated with various health benefits, including possible antitumor activity. It acts as an antioxidant that helps reduce oxidative stress, a contributor to numerous diseases. The compound may enhance immune response, further supporting antitumor activities and demonstrating antifungal properties that inhibit the growth of specific fungi, highlighting its multifunctional potential as a dietary supplement.
Side effects
HMRlignan™ is generally regarded as safe, with studies indicating no significant side effects at recommended dosages of 72 to 144 mg per day. Adverse effects are reported in less than 5% of cases, while rare side effects have not been documented. Caution is advised when combining HMRlignan™ with other medications due to undetermined potential interactions. No explicit contraindications exist; however, individuals with plant allergies should exercise care. The supplement has a low protein content (<1%), indicating minimal risk of allergic reactions. Though its safety profile appears robust, ongoing evaluations regarding drug interactions are recommended.
Dosage
Adults are generally advised to take HMRlignan™ at dosages ranging from 72 mg to 144 mg daily. Animal studies have suggested efficacy at around 15 mg/kg body weight, but the precise effective dose for humans remains unclear. Observations have shown maximum safe dosages could be up to 1200 mg acutely and 1350 mg for prolonged use. Typically available in capsule form, users can take one or two capsules per day. While specific timing for dosing is not critical, individual absorption factors are not well-documented, so adherence to recommended dosages is crucial for safety and effectiveness.
FAQs
Is HMRlignan™ safe?
Yes, HMRlignan™ has been shown to be safe in both animal and human studies, with no significant side effects reported at recommended doses.
How should I take HMRlignan™?
It can be taken as one or two capsules per day; no specific timing recommendations are available.
What benefits can I expect from HMRlignan™?
Potential benefits include antitumor effects, antioxidant activity, and antifungal properties, though extensive human trials are needed for confirmation.
Is HMRlignan™ a cure-all?
No, HMRlignan™ is not a cure-all; it is a supplement that may provide health benefits, typically over the long term.
Supplements Containing Hmr Lignan
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