Holy Basil Leaf Supercritical Extract
Also known as: Holy Basil, Tulsi, Ocimum sanctum, Ocimum tenuiflorum
Overview
Holy Basil, scientifically known as *Ocimum tenuiflorum* or *Ocimum sanctum*, is a green leafy plant native to Southeast Asia and holds significant importance in Ayurvedic medicine. This adaptogen is known for its ability to help the body manage stress and improve overall well-being. Holy Basil is characterized by its rich profile of active compounds, including eugenol, ursolic acid, rosmarinic acid, caryophyllene, and oleanolic acid, which contribute to its pharmacological properties. Despite its long history of use in traditional medicine, scientific research is still in the evolving phase, requiring more extensive human studies to determine the full extent of its benefits and optimal dosages. Current evidence from randomized controlled trials and pre-clinical studies indicates promising effects, particularly in stress reduction, cardiovascular health, and antioxidant activity.
Benefits
Holy Basil is recognized for several evidence-based benefits. One major effect is stress reduction; studies have demonstrated its ability to lower cortisol levels and improve mood in healthy individuals. Another significant benefit pertains to cardiovascular health; research indicates it can reduce total cholesterol and fasting blood glucose levels in older adults with metabolic conditions, with one study reporting a remarkable 60% reduction in fasting blood glucose. Additionally, its potent antioxidant properties protect against oxidative stress, further emphasizing its health benefits. Other noted effects include the enhancement of cognitive function and potential analgesic and anti-inflammatory properties, although more research is required in these areas. The benefits are especially pronounced in the general population and individuals with diabetes, evident within weeks of consistent use.
How it works
The primary biological mechanisms behind Holy Basil's effects involve its adaptogenic properties, which modulate the hypothalamic-pituitary-adrenal (HPA) axis, allowing the body to better handle stress. Its antioxidant compounds, such as rosmarinic acid and ursolic acid, neutralize free radicals and boost antioxidant enzyme activity. Additionally, Holy Basil exhibits cardioprotective effects by promoting peripheral vasodilation and inhibiting platelet aggregation, contributing to improved cardiovascular health. It interacts with various body systems, including the nervous system for mood stabilization, the cardiovascular system for heart health, and metabolic pathways for blood glucose regulation.
Side effects
Holy Basil is generally recognized as safe when consumed in moderation, but some considerations must be made regarding potential side effects and drug interactions. Most users tolerate it well, with few adverse effects reported. However, reproductive toxicity has been noted in animal studies, including impaired spermatogenesis and changes in the estrous cycle. While common side effects are not well-documented, individuals may experience unique reactions. There are concerns about interactions with blood sugar medications and blood thinners, making it essential for individuals taking these medications to consult healthcare providers. Furthermore, the use of Holy Basil is not advised during pregnancy or lactation due to the associated reproductive toxicity, highlighting a need for caution among specific populations.
Dosage
The recommended dosage for Holy Basil can vary based on the form used. A standardized extract of *Ocimum tenuiflorum* is typically advised at a range of 200-500 mg daily, noting that the extract should contain a minimum of 2.50% ursolic acid. Liquid extracts, particularly in a 1:1 form, can be taken at a dosage of 3-5 mL daily, while herbal tea preparations recommend 2-4 cups per day. Although no defined maximum safe dose exists, intakes exceeding 1 mg/kg body weight may pose reproductive toxicity risks. Timing suggests taking Holy Basil between meals or as directed by a healthcare provider. Optimizing absorption of active constituents can be achieved through dual extraction methods, enhancing both fat-soluble and water-soluble compounds.
FAQs
Is Holy Basil safe to use?
Generally considered safe, but consult a healthcare provider if you're pregnant, lactating, or taking other medications.
When should I take Holy Basil?
It can be taken between meals or as recommended by a healthcare provider for best results.
What benefits should I expect from using Holy Basil?
Users may experience reduced stress, improved mood, and potential enhancements in cardiovascular health and metabolic control.
Can Holy Basil replace my prescribed medications?
Holy Basil should not be viewed as a substitute for medical treatments; consult with healthcare personnel for appropriate use.
Research Sources
- https://professionals.gaiaherbs.com/Product/holy-basil-pro-caps – This source provides insights into the health benefits and applications of Holy Basil, emphasizing its adaptogenic properties and safety profile.
- https://medericenter.org/the-mederi-blog/holy-basil-an-herb-with-incomparable-benefits.html – The article discusses various benefits of Holy Basil, detailing its use in traditional medicine and supporting modern research.
- https://www.healthline.com/health/food-nutrition/basil-benefits – Healthline covers evidence-backed benefits of Holy Basil, including stress reduction and antioxidant effects, while also addressing potential safety concerns.
- https://www.fhi.no/contentassets/f08343d5155e413284f5c31a6b415b51/fhi-report-holy-basil-271123.pdf – This report presents a comprehensive risk assessment of Holy Basil, including reproductive toxicity concerns and overall health benefits.
- https://www.cochranelibrary.com/content?templateType=related&urlTitle=%2Fcentral%2Fdoi%2F10.1002%2Fcentral%2FCN-01555799&doi=10.1002%2Fcentral%2FCN-01555799&p_p_id=scolariscontentdisplay_WAR_scolariscontentdisplay&_scolariscontentdisplay_WAR_scolariscontentdisplay_action=related-content&p_p_lifecycle=0&p_p_mode=view&type=central&contentLanguage= – A Cochrane review outlining comprehensive benefits and safety assessments associated with the use of Holy Basil extract in various populations.