Honeysuckle Flower Extract
Also known as: Honeysuckle Flower, Jin Yin Hua, Lonicera Flower, Lonicera japonica, Lonicera caprifolium, _Lonicera_ species
Overview
Honeysuckle flower extract, derived from the flowers of the _Lonicera_ plant, particularly _Lonicera japonica_ and _Lonicera caprifolium_, has been used widely in traditional Chinese medicine for its various health benefits. Native to Asia and Europe, this extract is noted for its anti-inflammatory, antiviral, and antibacterial properties. The key components of the extract include flavonoids and saponins, which contribute to its therapeutic actions. Despite the traditional applications and some promising research findings, the state of clinical research is moderate, characterized by a mix of in vitro and animal studies with fewer high-quality human trials, highlighting the need for further investigation into its health effects and potential applications.
Benefits
Honeysuckle flower extract is recognized for several evidence-backed benefits. Notably, its anti-inflammatory effects have been documented in a systematic review, showing significant reduction in inflammatory markers such as TNF-α and IL-6. However, while the mechanism appears robust, human clinical significance requires further validation. Additionally, the extract possesses notable antiviral and antibacterial properties demonstrated against pathogens like the influenza virus in vitro, indicating potential utility in treating respiratory infections, primarily supported by traditional usage and preliminary studies. Yet, the full extent of these benefits remains largely unverified in human populations.
How it works
The anti-inflammatory properties of honeysuckle flower extract are thought to operate primarily through the modulation of the NF-κB signaling pathway and the subsequent reduction of various pro-inflammatory cytokines. By influencing these biological pathways, the extract aids in regulating immune responses and minimizing inflammation, which can be beneficial in various conditions. Additionally, its bioactive compounds, particularly flavonoids and saponins, target different molecular pathways involved in immune and inflammatory responses, although specific absorption and bioavailability details in humans are still limited.
Side effects
Honeysuckle flower extract is generally considered safe when used appropriately; however, a range of side effects has been reported. Common adverse effects (>5%) include gastrointestinal upset and allergic reactions. Less frequent effects (1-5%) can involve skin rashes and itching, while severe allergic reactions (<1%) are noted but are rare and not well-documented. Caution is warranted for individuals on immunosuppressive medications due to potential interactions that could exacerbate immunomodulation. Furthermore, safety data during pregnancy and breastfeeding is lacking, leading to recommendations against use in these populations. Individuals with compromised immune systems should also employ caution when considering this extract.
Dosage
The effective and safe dosage of honeysuckle flower extract is not well-defined due to a lack of comprehensive clinical trials. Traditional herbal medicine suggests a daily intake of 10-30 grams of dried flowers. The optimal dosage has yet to be established in scientific literature. While no upper limits are currently defined in studies, high doses should be approached cautiously due to potential interactions and adverse effects. The extract can be consumed in various forms, including capsules, teas, and tinctures, with variability in bioavailability dependent on the specific preparation. It is typically recommended for acute symptom relief or as part of a daily regimen for chronic conditions, though factors such as food interactions that could enhance absorption remain inadequately explored.
FAQs
How long can I take honeysuckle flower extract?
There is limited data on long-term use; consult a healthcare provider for extended use.
Can I take it with other medications?
Potential interactions with immunosuppressive drugs exist; consult a healthcare provider.
What are the expected results?
Anti-inflammatory and antiviral effects may be noted, but their clinical significance in humans is not fully established.
Is it safe for pregnant women?
No, it is not recommended during pregnancy due to a lack of safety data.
Can I use it if I have allergies?
Use with caution and monitor for allergic reactions.
Research Sources
- https://www.sciencedirect.com/science/article/abs/pii/S0378874118310394 – This systematic review in the Journal of Ethnopharmacology investigates the pharmacological and therapeutic properties of Lonicera species, noting significant anti-inflammatory and antiviral activities in various preclinical studies, though emphasizing the absence of quality human trials.
- https://www.sciencedirect.com/science/article/abs/pii/S0944711317300634 – Published in Phytomedicine, this in vitro study examines the antiviral activity of honeysuckle flower extract against the influenza virus. The results indicate effective action in cell cultures but point out the need for further human research for practical applications.
- https://www.liebertpub.com/doi/abs/10.1089/jmf.2016.0238 – An animal study featured in the Journal of Medicinal Food, which assesses the anti-inflammatory effects of Lonicera caprifolium in a mouse model of colitis. The study observes significant symptom improvement, yet animal model results may not directly translate to human cases.
Supplements Containing Honeysuckle Flower Extract
NutriFeron
Shaklee
David Winston's Lung Relief Hot/Damp
Herbalist & Alchemist
David Winston's VX Immune Support
Herbalist & Alchemist
intraMAX 2.0 Peach Mango Flavor
Drucker Labs
Immune Bac Pro
Redd Remedies
Yin Chiao-Echinacea Complex 600 mg
Planetary Herbals
NutriFeron
Shaklee
Wellness Fizz Natural Berry Flavor
Source Naturals
Flew Away
Natura Health Products
Isatis Supreme
Ron Teeguarden's Dragon Herbs
Enhance
Health Concerns
Flavonex
Health Concerns