Howaru Bifidobacterium Animalis Lactis Hn019
Also known as: Bifidobacterium lactis HN019, B. lactis HN019, Howaru Bifidobacterium, Bifidobacterium animalis subsp. lactis HN019
Overview
Bifidobacterium animalis subsp. lactis HN019 is a clinically studied probiotic strain derived from yogurt, recognized for its resilience in harsh gastrointestinal environments, such as high acidity and bile levels. This strain plays a crucial role in promoting gut health, enhancing microbiota balance, and supporting immune function. Research has demonstrated its efficacy in various clinical trials and systematic reviews, particularly in maintaining regular bowel movements and supporting the integrity of the intestinal barrier. B. lactis HN019 is typically administered through dietary supplements designed to optimize gut health and microbiome diversity, making it a prominent candidate in probiotic formulations.
Benefits
B. lactis HN019 is associated with several key health benefits supported by scientific evidence. Clinical trials indicate its efficacy in significantly reducing diarrhea incidence among children during critical periods. A systematic review highlights its role in improving immune function in the elderly, particularly through enhanced phagocytic activity. Although some studies suggest benefits for bowel regularity, others have not shown significant improvements in bowel movement frequency compared to placebo. Overall, the strain is particularly beneficial for young children and older adults, offering support for both gut health and immune response.
How it works
The primary mechanism of action for B. lactis HN019 involves its competitive ability to outcompete harmful bacteria for nutrients, thereby strengthening the gut barrier and maintaining tight junctions essential for gastrointestinal integrity. Additionally, it enhances immune responses by boosting phagocyte and natural killer cell activity. The strain may also impact gut-brain communication via serotonin production and contributes to overall microbiota health by generating short-chain fatty acids.
Side effects
B. lactis HN019 is generally regarded as safe, with minimal side effects reported. Approximately 1-5% of users may experience mild gastrointestinal symptoms, such as bloating and gas. Serious adverse reactions are uncommon, occurring in less than 1% of users, and are not clinically significant. There are no known severe drug interactions; however, individuals with compromised immune systems are advised to consult healthcare professionals before beginning supplementation. This probiotic is considered safe for users of all ages, including infants and the elderly, with no serious side effects documented.
Dosage
The recommended daily dosage of B. lactis HN019 typically ranges from 1.0 × 10^9 to 17.2 × 10^9 CFU, with optimal effects often observed between 5 × 10^9 and 5 × 10^10 CFU per day. There are no established upper safety limits, and higher doses have been effectively used in clinical settings. For best results, daily intake is suggested without specific timing considerations. This strain is commonly consumed through low-fat milk or as part of synbiotic products containing prebiotics, capitalizing on its resilience to acidic conditions for enhanced intestinal absorption.
FAQs
Is *B. lactis* HN019 safe for everyone?
Yes, it is generally considered safe; however, those with compromised immune systems should consult a healthcare professional.
What is the best time to take *B. lactis* HN019?
There’s no specific timing recommended; it is commonly taken daily.
When can I expect to see results from taking *B. lactis* HN019?
Improvements in gut health and immune function can be seen within 2-4 weeks, depending on the individual.
Can *B. lactis* HN019 cure gastrointestinal issues?
It is not a cure-all but can be a beneficial part of a healthy diet for supporting gut health.
Research Sources
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123270/ – This systematic review discusses the effectiveness of Bifidobacterium strains, particularly highlighting B. lactis HN019's role in gut health and diarrhea prevention in children. The rigorous analysis of multiple clinical trials provides strong evidence of its benefits.
- https://pubmed.ncbi.nlm.nih.gov/29382362/ – A clinical trial investigating B. lactis HN019 indicated significant improvements in immune function among elderly participants, showcasing its potential benefits for improving phagocytosis and overall immune response.
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