Hydrolyzed Marine Collagen Peptides
Also known as: Hydrolyzed Marine Collagen Peptides, Marine Collagen, Fish Collagen Peptides, HMCP
Overview
Hydrolyzed Marine Collagen Peptides (HMCP) are derived from collagen proteins found in marine sources, such as fish bones and scales. These peptides are created through a process called hydrolysis, which breaks down the collagen into smaller, more easily absorbed amino acid chains, including glycine, proline, and hydroxyproline. HMCP is primarily used as a nutricosmetic and protein supplement, targeting skin health and anti-aging. Research suggests potential benefits for joint health and muscle mass, although evidence is more robust for skin-related outcomes. HMCP is characterized by its high bioavailability, making it an effective source of amino acids essential for collagen synthesis. It is available in various forms, including powders and capsules, and is generally considered safe with minimal side effects. The quality of available evidence is generally good, with several systematic reviews and meta-analyses supporting its efficacy for skin health.
Benefits
Hydrolyzed Marine Collagen Peptides (HMCP) are primarily known for their benefits to skin health. Studies have demonstrated significant improvements in skin hydration and elasticity with HMCP supplementation. A meta-analysis showed improved hydration and elasticity compared to placebo. HMCP has also been shown to reduce wrinkles, contributing to anti-aging effects. These benefits are typically observed within 90 days of supplementation. While less robust, there is some evidence suggesting potential benefits for joint health and muscle mass. Most studies have focused on women aged 20-70 years, showing significant improvements in skin hydration and elasticity, with effect sizes indicating moderate to large benefits.
How it works
Hydrolyzed Marine Collagen Peptides (HMCP) primarily work by stimulating collagen synthesis within the body. The peptides are absorbed and utilized by fibroblasts, which are cells responsible for producing collagen. This process enhances the dermal matrix, improving skin hydration and supporting skin elasticity. HMCP interacts with collagen receptors and fibroblasts involved in collagen synthesis. Its high bioavailability, due to hydrolysis into smaller peptides, facilitates efficient absorption and utilization. The peptides provide the necessary amino acids, such as glycine, proline, and hydroxyproline, that are essential building blocks for new collagen formation.
Side effects
Hydrolyzed Marine Collagen Peptides (HMCP) are generally considered safe with minimal side effects. Rarely, individuals may experience mild gastrointestinal discomfort. Allergic reactions to fish or shellfish are a potential concern for those with relevant allergies. There are no significant drug interactions reported with HMCP supplementation. Pregnant or breastfeeding women should consult with their healthcare providers before using HMCP. While uncommon and rare side effects are not well-documented, it is always prudent to monitor for any adverse reactions when starting a new supplement. Individuals with known sensitivities to marine-derived products should exercise caution. Overall, HMCP has a favorable safety profile when used as directed.
Dosage
The recommended dosage of Hydrolyzed Marine Collagen Peptides (HMCP) typically ranges from 5 to 10 grams per day. A minimum effective dose is generally considered to be around 5 grams per day. While a maximum safe dose is not definitively established, dosages up to 10 grams per day are generally considered safe. HMCP is available in both powder and capsule forms, with no significant differences in efficacy noted between the two. It is best taken consistently, ideally with meals, to optimize absorption. Due to its hydrolyzed form, HMCP exhibits high bioavailability. No specific cofactors are required for its absorption or utilization.
FAQs
Is Hydrolyzed Marine Collagen Peptides safe to use?
HMCP is generally safe, but those allergic to fish or shellfish should avoid it. Consult a healthcare provider if you have concerns.
When is the best time to take Hydrolyzed Marine Collagen Peptides?
It is best taken consistently with meals to optimize absorption and ensure regular intake.
How long does it take to see results from Hydrolyzed Marine Collagen Peptides?
Improvements in skin hydration and elasticity are typically observed within 90 days of consistent supplementation.
Is Hydrolyzed Marine Collagen Peptides a cure for aging?
No, it is not a cure-all. Its benefits are primarily cosmetic, improving skin hydration, elasticity, and reducing wrinkles.
Research Sources
- https://pmc.ncbi.nlm.nih.gov/articles/PMC10180699/ – This systematic review and meta-analysis, encompassing 1721 patients across 26 RCTs, primarily focused on women and found significant improvements in skin hydration and elasticity with hydrolyzed collagen supplementation. The study highlights the potential of hydrolyzed collagen in enhancing skin health, although it acknowledges some limitations due to biases in certain included studies. The overall quality of evidence supports the use of hydrolyzed collagen for skin health benefits.
- https://pubmed.ncbi.nlm.nih.gov/33742704/ – This systematic review and meta-analysis, involving 1125 participants aged 20-70 years across 19 studies, demonstrated that hydrolyzed collagen reduced wrinkles and improved skin hydration and elasticity. The study provides strong evidence for the benefits of hydrolyzed collagen on skin health, particularly in reducing signs of aging. However, the scope was limited to skin health outcomes, suggesting a need for further research on other potential benefits.
- https://www.cureus.com/articles/207671-exploring-the-impact-of-hydrolyzed-collagen-oral-supplementation-on-skin-rejuvenation-a-systematic-review-and-meta-analysis – This systematic review supports the positive impact of hydrolyzed collagen on skin rejuvenation. It provides a comprehensive overview of existing evidence, highlighting the potential of hydrolyzed collagen in improving skin health. While the review does not include specific quantitative data, it offers valuable insights into the benefits of hydrolyzed collagen for skin rejuvenation.
- https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/effects-of-collagen-peptide-supplementation-on-cardiovascular-markers-a-systematic-review-and-metaanalysis-of-randomised-placebocontrolled-trials/D1BD51038B71D9A9BCA7880B1F6649F0 – This systematic review and meta-analysis examines the effects of collagen peptide supplementation on cardiovascular markers. The study analyzes randomized placebo-controlled trials to assess the impact of collagen peptides on various cardiovascular health indicators. The findings contribute to understanding the potential role of collagen supplementation in cardiovascular health.
- https://gomitasc3.com/wp-content/uploads/2023/05/Collagen-suplementation-on-skin-aging.pdf – This resource focuses on the effects of collagen supplementation on skin aging. It explores how collagen supplementation can impact various aspects of skin health related to aging. The document provides insights into the potential benefits of collagen in mitigating the effects of skin aging.
Supplements Containing Hydrolyzed Marine Collagen Peptides

Hair Renewal
Codeage

METAGLOW COLLAGEN
ZEND WELLNESS™

Collagen Beauty Complex Unflavored
SR Sports Research

Collagen Beauty Complex Strawberry Lemonade
SR Sports Research

Collagen Beauty Complex Watermelon Yuzu
SR Sports Research
Hair
Codeage

Bone Food Unflavored
California Gold Nutrition

Marine Collagen Peptides Unflavored
SR Sports Research

Collagen Beauty Complex Strawberry Lemonade
SR Sports Research

Premium Collagen Complex
O Nutritions

Collagen Complex
Purely Optimal
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Collagen
Custom Health Centers
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