Infinergy
Also known as: Infinergy, Dicaffeine Malate, Caffeine Malate
Overview
Infinergy, also known as dicaffeine malate or caffeine malate, is a synthetic compound combining caffeine and malic acid. Caffeine is a well-known stimulant found naturally in coffee, tea, and cocoa, while malic acid is an organic compound found in fruits like apples and grapes. It is primarily used in pre-workout supplements and energy drinks to enhance athletic performance, increase energy, and improve focus. The combination of caffeine and malic acid is thought to enhance the bioavailability and stability of caffeine, potentially reducing side effects like jitters and improving endurance. Research on Infinergy is moderately mature, with several studies examining its effects, often in combination with other ingredients. The available evidence is generally of good quality, including randomized controlled trials (RCTs) and reviews, although more independent verification is needed to fully understand its unique properties compared to caffeine alone.
Benefits
Infinergy has shown promise in enhancing athletic performance and improving energy levels. Studies indicate that supplements containing Infinergy can improve upper body resistance exercise performance. For example, research using a multi-ingredient pre-workout supplement (MIPS) that included Infinergy found significant improvements in reaction time, bench press peak power, and total number of repetitions completed compared to a placebo. The combination of caffeine and malic acid is believed to enhance energy levels and focus. Additionally, the same MIPS study found that the overall session rating of perceived exertion (RPE) was significantly lower with the supplement compared to the placebo, suggesting reduced perceived exertion. These benefits are most pronounced in athletes and fitness enthusiasts engaging in resistance training and other high-intensity activities.
How it works
Infinergy's mechanism of action primarily involves the effects of caffeine. Caffeine acts as an adenosine receptor antagonist, increasing alertness and energy by blocking adenosine's sleep-promoting effects. Malic acid may contribute to energy production by participating in the citric acid cycle (Krebs cycle), although its specific role in enhancing caffeine's effects is less clear. Caffeine stimulates the central nervous system (CNS), increasing alertness and reducing fatigue. Enhanced energy production and reduced perceived exertion can improve muscle performance. Adenosine receptors (A1 and A2A) are the primary targets of caffeine. The combination with malic acid may enhance the stability and bioavailability of caffeine, though specific data on this is limited.
Side effects
Infinergy is generally considered safe when consumed in recommended doses. Common side effects include jitters, anxiety, and insomnia, although the malic acid component may potentially reduce these effects compared to caffeine alone. Uncommon side effects (1-5%) may include increased heart rate and blood pressure, though studies have shown these effects to be minimal and not clinically significant. Rare side effects are uncommon but can include allergic reactions or interactions with other medications. Caffeine can interact with certain medications, such as antidepressants, and reduce the effectiveness of others, like certain antibiotics. It is contraindicated for pregnant or breastfeeding women and individuals with certain medical conditions (e.g., high blood pressure, heart disease) should consult a healthcare provider before use. Children, adolescents, and older adults should use with caution due to potential sensitivity to caffeine.
Dosage
The effective dose of Infinergy typically includes around 100-200 mg of caffeine combined with malic acid. The optimal dose is often within the range of 150-300 mg of caffeine per serving, combined with an equivalent amount of malic acid. The maximum safe dose of caffeine is generally considered to be around 400 mg per day, but this can vary based on individual tolerance and other factors. It is best taken 30-60 minutes before exercise or physical activity. Infinergy is available in powder or capsule form; the powder form is often mixed with water or another beverage. The malic acid component may enhance the absorption and stability of caffeine. Adequate hydration is recommended when using Infinergy.
FAQs
Is Infinergy safe?
Infinergy is generally safe when used as directed. Individuals should be cautious of caffeine sensitivity and potential interactions with medications. Consult a healthcare provider if you have underlying health conditions.
When should I take Infinergy?
It is best taken 30-60 minutes before exercise to enhance performance and energy levels. This timing allows the caffeine to take effect during your workout.
What results can I expect from Infinergy?
Users can expect improved athletic performance, increased energy, and enhanced focus. The effects are primarily due to the caffeine component of Infinergy.
Does Infinergy offer unique benefits beyond caffeine alone?
Some believe Infinergy provides unique benefits due to the malic acid, but the evidence is mixed. More research is needed to confirm these claims and understand the specific contributions of malic acid.
Research Sources
- https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2024.1323408/full – This study investigated the effects of a multi-ingredient pre-workout supplement (MIPS) containing Infinergy on resistance-trained individuals. The results showed significant improvements in reaction time, bench press peak power, and total number of repetitions completed compared to a placebo. The study also reported a lower rating of perceived exertion (RPE) during the supplement trial, indicating reduced perceived effort.
- https://www.dovepress.com/effects-of-p-synephrine-in-combination-with-caffeine-a-review-peer-reviewed-fulltext-article-NDS – This systematic review and meta-analysis examined the effects of p-synephrine in combination with caffeine. The review found no significant adverse effects with the combination and reported increased lipolysis, energy expenditure, and athletic performance. While not specifically focused on Infinergy, it provides valuable context on the effects of caffeine in combination with other ingredients.
- https://www.mdpi.com/2072-6643/8/6/354 – This randomized, double-blinded, placebo-controlled RCT assessed the safety and efficacy of a caffeine and malic acid combination. The study found no adverse effects on liver enzymes, kidney function, or blood chemistries. The results also indicated improved athletic performance without significant side effects, supporting the potential benefits of the Infinergy combination.
Supplements Containing Infinergy

Mr Hyde Pre Workout Amplifier Orange Guava
PS ProSupps

Mr Hyde Pre Workout Amplifier Grape
PS ProSupps

Mr Hyde Pre Workout Amplifier Blue Razz
PS ProSupps

ENGN Pre-Workout Engine Fruit Punch
Evlution Nutrition

ENGN Pre-Workout Engine Watermelon
Evlution Nutrition

Pre Watermelon
NutraBio

Mr Hyde Intense Pre Workout Berry Blast
PS ProSupps