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Jojoba Oil

Also known as: Jojoba oil, Jojoba seed oil, Simmondsia chinensis

Overview

Jojoba oil is extracted from the seeds of the *Simmondsia chinensis* shrub, native to North America. Unlike most oils, it primarily consists of wax esters, giving it unique properties. It is widely used in skincare, haircare, and pharmaceutical formulations due to its non-greasy texture and fast absorption. Jojoba oil is rich in monounsaturated esters and exhibits antioxidant, anti-inflammatory, and antimicrobial properties. Research on jojoba oil includes extensive studies on its chemical composition and pharmacological activities, but clinical trials on specific health benefits are limited. It is generally considered safe for external use, with internal consumption not recommended. The quality of available evidence is primarily based on chemical properties and in vitro studies, with fewer large-scale clinical trials.

Benefits

Jojoba oil exhibits antioxidant, anti-inflammatory, and antimicrobial properties, primarily demonstrated in in vitro studies. It is commonly used in skincare for its moisturizing and anti-acne effects. Some studies suggest it may benefit skin conditions like acne and psoriasis due to its anti-inflammatory actions. However, the clinical evidence supporting these benefits is limited, and the effect sizes are not well-quantified due to the lack of large-scale clinical trials. While immediate skin hydration effects are observed, the long-term benefits require further investigation.

How it works

Jojoba oil's mechanism of action involves antioxidant and anti-inflammatory pathways, although the specific mechanisms are not fully understood. It is transdermally absorbed, potentially affecting lipid metabolism, as indicated by increased serum non-esterified fatty acids (NEFA) in animal studies. However, the bioavailability and systemic effects in humans are not well-studied. Its interaction with specific molecular targets remains undefined, but its chemical composition suggests it can influence skin barrier function and reduce inflammation.

Side effects

Jojoba oil is generally considered safe for external use. Common side effects are rare, but some individuals may experience skin irritation. Uncommon and rare side effects are not well-documented. There are no documented drug interactions. Internal use is contraindicated. While there are no specific warnings for pregnant or breastfeeding women, caution is advised. Overall, jojoba oil has a favorable safety profile when used topically, but users should perform a patch test to check for skin sensitivity before widespread application.

Dosage

For skincare, a few drops of jojoba oil are typically sufficient. The optimal dosage varies by application. There is no established minimum effective dose for specific health benefits. The maximum safe dose for external use is not established, but it is generally considered safe. Cold-pressed oil is preferred to preserve its nutrients. Jojoba oil is efficiently absorbed transdermally. There are no documented required cofactors. It is important to avoid internal consumption.

FAQs

How should I use jojoba oil?

Use as directed for external applications. Perform a patch test to check for skin sensitivity before applying it to larger areas. Avoid internal consumption and eye contact.

Is jojoba oil safe?

Jojoba oil is generally safe for external use. However, avoid internal consumption. If you experience skin irritation, discontinue use.

When should I apply jojoba oil?

Apply as needed for skin hydration. Consistent use may be required to observe other potential benefits. It can be used daily as part of a skincare routine.

What are the expected results from using jojoba oil?

You can expect immediate skin hydration. Other benefits, such as reduced inflammation or acne, may require consistent use over time. Results can vary.

Can I ingest jojoba oil?

No, jojoba oil is not intended for internal use. It is primarily for external application to the skin and hair. Internal consumption is contraindicated.

Research Sources

https://pmc.ncbi.nlm.nih.gov/articles/PMC8197201/ – This review article highlights the chemical composition and pharmacological activities of jojoba oil, noting its antioxidant, anti-inflammatory, and antimicrobial properties. The study primarily focuses on in vitro and chemical properties rather than clinical effects, suggesting potential but not definitively proven health benefits.
https://pmc.ncbi.nlm.nih.gov/articles/PMC9231140/ – This experimental study evaluates the chemical properties of 15 elite jojoba lines, finding that chemical properties vary by genotype, affecting fatty acid composition. While the study provides insights into the variability of jojoba oil's chemical makeup, it does not directly address human health benefits.
https://pmc.ncbi.nlm.nih.gov/articles/PMC6780807/ – This animal study investigates the effects of transdermal administration of jojoba oil on lipid metabolism in mice, reporting increased serum NEFA levels. The findings suggest that jojoba oil can be absorbed through the skin and influence lipid metabolism, but the relevance to human health requires further investigation.
https://pubmed.ncbi.nlm.nih.gov/38695844/ – This study investigates the use of jojoba oil in a novel topical formulation containing cannabidiol (CBD) for the treatment of psoriasis. The formulation showed promise in improving skin hydration and reducing inflammation associated with psoriasis, suggesting a potential therapeutic application of jojoba oil in combination with other active ingredients.
https://vivanaturals.com/products/jojoba-oil – This is a product page for Viva Naturals Jojoba Oil. It highlights the benefits of jojoba oil for skin and hair, emphasizing its moisturizing and nourishing properties. It also mentions that their jojoba oil is cold-pressed to preserve its natural nutrients.