Kacip Fatimah Extract
Also known as: Kacip Fatimah, Fatimah's Vine, Labisia pumila
Overview
Labisia pumila, commonly known as Kacip Fatimah, is a plant native to Southeast Asia revered for its medicinal properties, particularly among women. Traditionally used in Southeast Asian medicine, it is primarily recognized for alleviating menopausal symptoms and other reproductive health issues. The plant contains bioactive compounds such as flavonoids and phenolic acids, which are believed to contribute to its health-promoting effects. Although there are emerging studies evaluating its efficacy, the research maturity level remains limited, underscoring the need for further comprehensive clinical trials to validate its benefits and safety profiles. Kacip Fatimah is typically administered as an aqueous extract, often used in conjunction with other herbs in dietary formulations.
Benefits
Labisia pumila is primarily associated with alleviating symptoms of menopause, including hot flushes. Clinical research demonstrates that participants experienced a 65% improvement in such symptoms after 12 weeks of treatment, compared to a 60% improvement in a placebo group. Furthermore, the extract may positively influence lipid profiles by reducing serum low-density lipids and triglycerides. The primary benefits are most pronounced in peri-menopausal and menopausal women, making it a significant herbal remedy for this population. The evidence suggests moderate effect sizes overall, highlighting the necessity for ongoing research to establish definitive clinical significance.
How it works
Labisia pumila is believed to exert its effects primarily through hormonal modulation, particularly by influencing levels of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). These actions suggest a potential role in alleviating menopausal symptoms by balancing endocrine function. Though the molecular targets remain largely undefined, the bioactive flavonoids and phenolic compounds present may contribute to its therapeutic effects, signaling interactions that warrant further investigation.
Side effects
Labisia pumila is generally regarded as safe with high tolerance levels observed in animal studies. However, common side effects have not been thoroughly documented in humans, but anecdotal evidence suggests possible gastrointestinal upset as a general risk associated with herbal supplements. Rare and uncommon side effects remain mostly unreported due to the lack of extensive human studies. Caution is advised for specific populations, particularly pregnant or breastfeeding women, due to insufficient safety data. Additionally, persons on hormonal medications should use caution given the potential for drug interactions and hormonal impacts.
Dosage
Currently, the minimum effective dose for Labisia pumila has not been firmly established. It is typically incorporated into formulations alongside other herbs, such as Eurycoma longifolia, particularly in products like Nu-femmeTM. The data suggest high tolerance in animal studies but limited human dosing guidelines are available. Therefore, anyone considering supplementation should consult a healthcare provider. There are no specific timing recommendations for administration, and known factors influencing absorption are yet to be documented.
FAQs
Is Kacip Fatimah safe for everyone?
While generally considered safe, Kacip Fatimah should be avoided by pregnant or breastfeeding women and those with hormonal imbalances without consulting a healthcare professional.
How quickly can I expect to see results with Kacip Fatimah?
Some users report improvement in menopausal symptoms within 12 weeks of regular supplementation.
Can I take Kacip Fatimah with my medication?
If you are taking hormonal medications, consult your healthcare provider before starting Kacip Fatimah to avoid potential interactions.
What form does Kacip Fatimah come in?
Kacip Fatimah is primarily used as an aqueous extract, but it may also be available in capsules or as part of herbal blends.
Is it a substitute for my prescribed treatment?
No, Kacip Fatimah should not be seen as a substitute for prescribed medical treatments. Always discuss with your healthcare provider.
Research Sources
- https://foodandnutritionresearch.net/index.php/fnr/article/view/3665 – This randomized controlled trial evaluated the effect of Kacip Fatimah extract on peri-menopausal women's hot flush symptoms, finding significant improvements in comparison to placebo, although some measures showed no significant difference.
- https://www.mdpi.com/1422-0067/12/8/5238 – The review discusses various plant extracts, including Labisia pumila, and highlights its potential in improving symptoms of polycystic ovary syndrome (PCOS), though rigorous studies specifically on Labisia pumila are lacking.
- https://www.mdpi.com/1424-8247/14/2/142 – An animal study that assessed the safety and tolerance of Labisia pumila, reporting a high degree of tolerance in rats, but emphasizes the limitations of animal research in human applications.
- https://medic.upm.edu.my/upload/dokumen/2019060311353816_MJMHS_June_2019.pdf – This document reviews traditional uses of Labisia pumila and presents potential benefits. However, it notes the necessity for more systematic reviews and high-quality clinical data.
- https://dom-pubs.onlinelibrary.wiley.com/doi/full/10.1111/dom.15229 – A systematic review on herbal remedies for menopausal symptoms, which includes Labisia pumila, noting moderate evidence but calling for rigorous research and systematic reviews focusing on this specific herb.
