Lactiplantibacillus Plantarum Rsb11
Also known as: Lactobacillus plantarum, Probiotic bacteria, Lactiplantibacillus plantarum
Overview
*Lactiplantibacillus plantarum* is a probiotic bacterium naturally occurring in various fermented foods, such as sauerkraut and kimchi. It is classified as a probiotic supplement, utilized primarily to support gastrointestinal health and modulate immune responses. The existing body of research on *L. plantarum* is extensive, demonstrating its effectiveness in alleviating gastrointestinal symptoms and enhancing immune functions. Although the specific Rsb11 strain requires more targeted studies, substantial evidence from various strains highlights the health benefits attributed to this probiotic. Common forms of *L. plantarum* include capsules and fermented food products, making it widely accessible for use.
Benefits
[{"benefit":"Gastrointestinal Health","evidence_strength":"Strong","description":"*L. plantarum* has demonstrated significant benefits in reducing abdominal pain and improving gut health, evidenced by multiple studies."},{"benefit":"Immune System Modulation","evidence_strength":"Strong","description":"It effectively regulates cytokine levels, improving anti-inflammatory responses and reducing inflammation-related markers."},{"benefit":"Cardiovascular Health","evidence_strength":"Moderate","description":"Some studies suggest potential cholesterol-lowering effects, which may contribute to heart health."},{"benefit":"Glucose Metabolism","evidence_strength":"Emerging","description":"Evidence indicates potentially improved glucose and lipid metabolism, particularly in type 2 diabetes, though human data remains limited."}]
How it works
*Lactiplantibacillus plantarum* operates primarily through the modulation of gut microbiota, enhancing the intestinal barrier and influencing immune responses by regulating cytokine production. It interacts mainly with the gastrointestinal and immune systems, targeting cytokines including IL-4, IL-10, TNF-α, and IFN-γ. While it is not systemically absorbed, it exerts localized effects within the gut, contributing to overall health.
Side effects
{"common":"Mild gastrointestinal symptoms such as bloating or gas.","uncommon":"Rare instances of allergic reactions or exacerbation of underlying conditions may occur.","rare":"There is a potential risk of infections, particularly in immunocompromised individuals.","drug_interactions":"Generally minimal, but caution is advised in individuals taking immunosuppressive therapies.","contraindications":"Should be avoided in those with severe immunocompromised states. Pregnant or breastfeeding women should consult with a healthcare provider due to limited safety data."}
Dosage
{"minimum_effective_dose":"Typically ranges from 1-10 billion CFU per day.","optimal_dosage_ranges":"Depends on health conditions; usually advised between 1-20 billion CFU daily.","maximum_safe_dose":"Not well established, but generally considered safe up to 20 billion CFU.","timing_considerations":"Best taken with food to enhance survival through stomach acid.","form_specific_recommendations":"Common forms include capsules and fermented food products."}
FAQs
How should I store Lactiplantibacillus plantarum supplements?
Store in a cool, dry place and follow specific instructions on the label to maintain viability.
Is Lactiplantibacillus plantarum safe for everyone?
Generally safe, but consult a healthcare provider if you are immunocompromised or have specific health concerns.
When is the best time to take Lactiplantibacillus plantarum?
It is best taken with meals to enhance its effectiveness.
What results can I expect from using Lactiplantibacillus plantarum?
Results may vary based on individual health status and the specific strain used.
Are all probiotics the same?
No, strain-specific effects are crucial; not all probiotics provide the same benefits.
Research Sources
- https://pubmed.ncbi.nlm.nih.gov/38816672/ – This systematic review and meta-analysis assessed 135 studies, including 18 that directly evaluated health benefits of *L. plantarum*, highlighting its role in improving periodontal health, reducing abdominal pain, and lowering cholesterol levels.
- https://pubmed.ncbi.nlm.nih.gov/38777458/ – This study reported that *L. plantarum* may improve glucose and lipid metabolism in type 2 diabetes through a systematic review and included five randomized controlled trials assessing fasting glucose levels.
- https://www.frontiersin.org/journals/immunology/articles/10.3389/fimmu.2021.643420/full – A meta-analysis involving 18 randomized controlled trials revealed that *L. plantarum* plays a significant role in modulating cytokine levels, enhancing immunity, albeit with variability across different strains and dosages.