Get Your Personalized Supplement StackSupplement Stack Quiz

Lactium

Also known as: Lactium®, alpha-casozepine, Alpha-S1 casein hydrolysate

Overview

Lactium® is a dietary supplement derived from alpha-S1 casein, a milk protein hydrolysate that includes the decapeptide alpha-casozepine. Renowned for its calming effects, Lactium® is primarily utilized to alleviate stress, anxiety, and sleep disturbances without causing sedation or addiction. This supplement enhances relaxation by acting on the central nervous system, supported by multiple clinical studies showing positive outcomes for sleep quality and stress reduction. While research on Lactium® demonstrates promising benefits, it is essential to acknowledge that some studies exhibit limitations, such as small participant sizes and short intervention durations.

Benefits

Recent clinical trials have indicated a range of benefits from Lactium® supplementation. A notable double-blind, placebo-controlled trial showed significant improvements in sleep parameters, such as total sleep time and reduced wake after sleep onset, among participants taking Lactium® combined with L-theanine. Furthermore, Lactium® is evidenced to lower stress and anxiety levels, demonstrated by reductions in cortisol and blood pressure during stress tests. Populations most likely to benefit include adults with sleep issues or anxiety, particularly seeing moderate to significant improvements in sleep metrics over 4 to 8 weeks of consistent use.

How it works

Lactium® functions primarily through the action of alpha-casozepine, which modulates physiological responses linked to stress, particularly blood pressure and cortisol levels. By influencing central nervous system pathways, it effectively reduces perceived stress and anxiety. Lactium® may also affect gut microbiota, which have been associated with sleep and anxiety, further elucidating its supportive role in relaxation and improved sleep cycles.

Side effects

Lactium® is reported to be safe for most individuals, with no significant side effects related to sedation, addiction, or adverse reactions. In clinical evaluations, side effects are rare; none were reported in studies involving large groups of participants. There is insufficient data regarding safety in special populations, including pregnant or breastfeeding women and children, as well as individuals with severe medical conditions. Importantly, no drug interactions have been identified with Lactium®, indicating a favorable safety profile. However, as with any supplement, it is advisable for individuals to consult healthcare professionals, especially when combining with other medications.

Dosage

The effective dosage of Lactium® typically ranges from 150 mg to 300 mg per day, with some studies indicating 150 mg as the minimum effective dose. Optimal results for sleep benefits have been noted after 4 to 8 weeks of supplementation. Though no defined maximum safety threshold exists, higher doses have not shown toxic effects in the reviewed studies. Lactium® is usually administered in capsule or tablet form, with no specific timing recommended; it can be taken as part of a daily routine.

FAQs

How long does it take to see effects?

Benefits on sleep quality were observed after 4 and 8 weeks of regular supplementation.

Is it safe for long-term use?

There is no evidence of adverse effects with long-term use, but further studies are needed to confirm long-term safety.

Can it be used with other supplements?

There is no significant evidence of interactions, but caution is advisable when combining with other supplements or medications.

Is it addictive?

No, Lactium® is not associated with addiction.

Are there any side effects?

No significant side effects have been documented in extensive clinical studies.

Research Sources

https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2024.1419978/full – This study assessed the effects of Lactium® and L-theanine on sleep disturbances in 40 participants over 8 weeks, showcasing significant improvements in sleep-related parameters and gut microbiota composition.
https://www.lactium.com/what-is-lactium/alpha-casozepine-with-relaxing-properties/ – Lactium® contains alpha-casozepine, recognized for its stress-relieving properties. This source provides an overview of its effects on anxiety and sleep quality based on existing clinical research.
https://pubmed.ncbi.nlm.nih.gov/38953043/ – A summary of multiple studies on Lactium® demonstrating its effectiveness in reducing stress indicators, such as blood pressure and cortisol levels, evidencing its potential for anxiety management.
https://onlinelibrary.wiley.com/doi/10.1155/2020/3792390 – An exploration of the effects of Lactium® and Zizyphus on sleep enhancement, although results indicated limited improvements due to the short study duration despite rigorous methodology.
https://www.semanticscholar.org/paper/Exploring-the-Effect-of-Lactium%E2%84%A2-and-Zizyphus-on-A-Scholey-Benson/8a657b0bd728493cceab7375cda9cafa987ab71a – This article presents findings from a double-blind trial involving Lactium® and Zizyphus, showing the need for more comprehensive studies due to mixed results in sleep quality improvements.