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Lactobacillus Bulgaricus

Also known as: Lactobacillus delbrueckii subsp. bulgaricus, Lactobacillus bulgaricus, L. bulgaricus, Bulgarian yogurt bacteria

Overview

*Lactobacillus delbrueckii* subsp. *bulgaricus*, commonly known as *L. bulgaricus*, is a probiotic bacterium predominantly found in fermented dairy products like yogurt. It plays a crucial role in yogurt production, often used in conjunction with *Streptococcus thermophilus*. This bacterium is known for its ability to ferment lactose, producing lactic acid, which contributes to the characteristic taste and texture of yogurt. As a probiotic, it is consumed for its potential health benefits, particularly related to gut health and digestion. While research is ongoing, evidence varies regarding its specific health benefits, with some studies showing potential improvements in certain blood parameters. It is available in fermented foods and as a dietary supplement.

Benefits

Some studies suggest that *L. bulgaricus* may help reduce certain blood parameters, such as AST levels, and improve triglyceride levels, although these effects are not consistently observed across all studies. Evidence supporting its use for specific health conditions beyond general gut health is limited. The clinical significance of observed effects is often small and not consistently significant across studies. Benefits may vary by population, but there is insufficient data to make specific recommendations. More research is needed to fully understand the extent and consistency of these benefits.

How it works

*L. bulgaricus* primarily functions by modulating the gut microbiota, which can improve digestion and support immune function. It interacts mainly with the gastrointestinal system, influencing gut barrier function and immune response. As a probiotic, it colonizes the gut rather than being absorbed like a drug. Its fermentation of lactose into lactic acid contributes to the gut environment, potentially affecting the balance of other microorganisms. The precise molecular targets and detailed mechanisms are still under investigation.

Side effects

*L. bulgaricus* is generally considered safe for consumption. Common side effects include mild gastrointestinal symptoms such as bloating or gas. Uncommon side effects are not well-documented. Rare side effects may include infections in severely immunocompromised individuals. No significant drug interactions have been reported. It is generally not recommended for severely immunocompromised individuals. Caution is advised in pregnant or breastfeeding women due to limited data. While considered safe, it should be used cautiously in individuals with compromised immune systems to avoid potential complications.

Dosage

The minimum effective dose of *L. bulgaricus* is not well-established. Optimal dosage ranges typically vary depending on the source, whether from fermented foods or supplements. A maximum safe dose has not been definitively established, but high doses are generally well-tolerated. It is often recommended to take it with food to enhance survival through the stomach's acidic environment. It is commonly available in yogurt or as a supplement in capsule form. No specific cofactors are required for its activity.

FAQs

Is *L. bulgaricus* safe to consume?

Yes, it is generally safe and well-tolerated for most people. However, immunocompromised individuals should exercise caution.

When is the best time to take *L. bulgaricus*?

It is best taken with meals to enhance its survival through the stomach's acidic environment.

What benefits can I expect from taking *L. bulgaricus*?

It may improve gut health, but specific benefits can vary from person to person. It is not a cure-all for digestive issues.

Can *L. bulgaricus* cure diarrhea?

Some studies suggest it may help with diarrhea, but it is not a guaranteed cure and other treatments may be necessary.

Research Sources

https://www.frontiersin.org/journals/gastroenterology/articles/10.3389/fgstr.2022.983075/full – This systematic review analyzed 19 randomized trials with 1412 participants and found that *L. bulgaricus* showed some benefits in reducing AST levels and triglycerides, but not consistently across all parameters. The study's quality was rated as moderate due to heterogeneity among the included studies, indicating variability in outcomes.
https://pmc.ncbi.nlm.nih.gov/articles/PMC10890272/ – This systematic review and meta-analysis focuses on the effectiveness of *L. acidophilus* and *L. bulgaricus* in treating diarrhea compared to placebo. The study assesses the effectiveness of these probiotics in treating diarrhea compared to placebo. The study's quality was rated as moderate due to the specific focus on diarrhea treatment.
https://pmc.ncbi.nlm.nih.gov/articles/PMC6927028/ – This systematic review with meta-analysis examines the effects of probiotics, including *Lactobacillus* spp., on nonalcoholic fatty liver disease (NAFLD) and other conditions. The study's quality was rated as moderate to high due to the comprehensive analysis across different probiotic strains.
https://onlinelibrary.wiley.com/doi/10.1155/2019/1484598 – This study investigates the impact of probiotics on various health outcomes. It provides insights into the potential benefits of probiotics, including *Lactobacillus* species, in managing different health conditions. Further details on the specific findings related to *L. bulgaricus* would require a closer examination of the full text.
https://frontiersin.figshare.com/articles/dataset/DataSheet_1_A_systematic_review_and_meta-analysis_of_Lactobacillus_acidophilus_and_Lactobacillus_bulgaricus_for_the_treatment_of_diarrhea_docx/21523248 – This dataset accompanies a systematic review and meta-analysis of *Lactobacillus acidophilus* and *Lactobacillus bulgaricus* for the treatment of diarrhea. It provides the underlying data used in the analysis, allowing for a detailed examination of the evidence supporting the use of these probiotics for managing diarrhea.