Lactobacillus Casei Idcc 3451
Also known as: Lactobacillus casei IDCC 3451, L. casei, Lacticaseibacillus casei, Lacticaseibacillus casei IDCC 3451
Overview
Lacticaseibacillus casei IDCC 3451 is a probiotic strain initially isolated from infant feces. This strain is notable for its role in enhancing gut health, improving the digestibility of proteins, particularly from plant sources. It exhibits proteolytic activity, which aids in breaking down proteins into amino acids that can be more readily absorbed by the body. Despite the emerging nature of the research surrounding this specific strain, it has undergone safety assessments demonstrating its viability as a probiotic. The majority of current literature focuses on its metabolic features and potential health benefits, indicating it may serve as an effective probiotic supplement, though evidence of its clinical efficacy remains somewhat limited.
Benefits
Lacticaseibacillus casei IDCC 3451 primarily enhances the digestibility of plant-based proteins such as legumin, with significant evidence shown in animal studies. In a controlled mouse model, it increased essential amino acid concentrations by 1.41 times compared to a high-protein diet alone, highlighting its potential for individuals following high-protein or plant-based diets. Secondary benefits may include support for gut health and the immune system, but more human studies are needed to confirm these effects. Overall, while evidence is promising, limitations in sample sizes and study depth suggest that further research is necessary to fully establish benefits in human populations.
How it works
Lacticaseibacillus casei IDCC 3451 works primarily through proteolytic activity, enhancing the digestion and absorption of proteins in the gastrointestinal tract. This beneficial bacteria breaks down complex protein structures into simpler peptides and amino acids, which can then be easily assimilated by the body. Its interaction with the gut microbiome may also promote a favorable environment for microbial balance, contributing to overall digestive health.
Side effects
Generally regarded as safe, Lacticaseibacillus casei IDCC 3451 is well-tolerated by most individuals; however, some may experience mild gastrointestinal symptoms such as gas or bloating. Uncommon or rare side effects have not been documented significantly in available studies. While there are no known drug interactions, individuals with specific health concerns, or those who are pregnant or breastfeeding, should consult healthcare professionals prior to use due to limited evidence on safety in these populations. The overall safety profile shows no significant cytotoxicity or antimicrobial resistance, reinforcing its potential as a safe probiotic choice.
Dosage
Currently, no minimum effective dose has been established for Lacticaseibacillus casei IDCC 3451 in human studies, and optimal dosage ranges are not well-specified in the literature. Typically, this probiotic is consumed in supplement form or through fermented products, with professionals often recommending use under medical guidance, especially in special populations. As precise dosing and timing parameters are not defined in existing research, practitioners may tailor recommendations based on individual needs and responses, while also considering safe thresholds based on general probiotic usage guidelines.
FAQs
Is Lacticaseibacillus casei IDCC 3451 safe for everyone?
It is generally considered safe for most individuals, but those with specific health issues or pregnant/breastfeeding women should consult a healthcare professional.
How does it impact protein digestion?
This probiotic enhances the digestibility of proteins, particularly plant-based types, facilitating the breakdown into absorbable amino acids.
What are the common side effects?
Typically mild and may include gas or bloating, but other side effects are rare or not well-documented.
How should I take it?
Usage should be under healthcare guidance, as there are no specific timing recommendations detailed in current studies.
Are there any known drug interactions?
No significant interactions have been identified, making it a safe option when taken separately from other medications.
Research Sources
- https://pubmed.ncbi.nlm.nih.gov/33421164/ – This study provides genomic characterization and safety evaluation for Lacticaseibacillus casei IDCC 3451, confirming its safety profile with no significant cytotoxic effects.
- https://pubmed.ncbi.nlm.nih.gov/37204697/ – An animal model study demonstrated that co-administering Lacticaseibacillus casei with legumin proteins significantly enhances amino acid concentrations, providing a foundation for its application in protein digestibility.
- https://www.mdpi.com/2072-6643/12/11/3443 – This systematic review discusses the general benefits of Lactobacillus casei on gut health and immune function, providing relevant context for the IDCC 3451 strain.
- https://www.mdpi.com/2072-6643/16/14/2243 – Another systematic review assessing Lactobacillus casei notes its potential impacts on digestive health, helping to corroborate findings applicable to Lacticaseibacillus casei IDCC 3451.
- https://www.webmd.com/vitamins/ai/ingredientmono-1670/lacticaseibacillus-casei – This resource provides an overview of Lacticaseibacillus casei, including its uses, benefits, and safety information, although it does not specifically address IDCC 3451.
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