Lactobacillus Delbrueckii Bulgaricus
Also known as: Lactobacillus bulgaricus, Lactobacillus delbrueckii var. bulgaricus, Bulgaricus, Lactobacillus delbrueckii, L. bulgaricus, Lactobacillus delbrueckii subsp. bulgaricus
Overview
Lactobacillus delbrueckii subsp. bulgaricus is a well-known probiotic bacterium primarily involved in the fermentation of dairy products, particularly yogurt. This strain thrives in acidic environments and exhibits significant bile tolerance, allowing it to survive transit through the gastrointestinal tract. As a dietary supplement, it is associated with improved gastrointestinal health and enhanced lipid profiles, supported by systematic reviews and randomized controlled trials that have established its probiotic functionalities, although variations in the strength of evidence exist. The application of this probiotic is prevalent in both dietary supplements and fermented foods, positioning it as a staple in functional nutrition aimed at bolstering overall health and wellness.
Benefits
The benefits of Lactobacillus delbrueckii subsp. bulgaricus include: 1. Lipid Profile Improvement: A randomized controlled trial demonstrated significant reductions in blood triglyceride levels among overweight individuals after 12 weeks of supplementation, indicating its potential role in cardiovascular health. 2. Antimicrobial Properties: This strain has shown effectiveness against pathogens such as Escherichia coli and Staphylococcus aureus, although its efficacy against Helicobacter pylori remains less conclusive. 3. Secondary Benefits: It possesses antimicrobial and anti-inflammatory characteristics that support gut health and enhance immune modulation. Some evidence suggests limited efficacy in diarrhea treatment, though specific populations, especially overweight individuals, may experience notable health improvements.
How it works
Lactobacillus delbrueckii subsp. bulgaricus functions by modulating gut microbiota, producing organic acids, and creating antimicrobial substances that inhibit pathogenic bacteria growth. It significantly influences lipid metabolism via interactions with the gastrointestinal and immune systems, promoting a healthier balance of gut flora. Its ability to survive acidic and bile conditions enhances effective colonization, which, in turn, maximizes its beneficial effects related to fat digestion and absorption.
Side effects
Lactobacillus delbrueckii subsp. bulgaricus is generally recognized for its safety profile, with minimal adverse reactions documented. Common side effects are not specified, and rare reactions, if they occur, affect less than 1% of users. Immunocompromised individuals are advised to exercise caution, even though the documented risks remain minimal. Additionally, potential interactions with medications, particularly proton-pump inhibitors, could influence gut flora balance. Overall, this probiotic is considered safe for the general population, though monitoring for unusual responses is prudent for sensitive individuals.
Dosage
The recommended dosage for Lactobacillus delbrueckii subsp. bulgaricus typically ranges from 1 x 10^8 to 3 x 10^9 colony-forming units (CFU) per day. Clinical studies suggest that an optimal dose of 1 x 10^8 CFU can effectively improve lipid profiles. While no definitive upper limit or maximum safe dosage has been established, consistent daily intake is advisable. The strain's inherent resistance to digestive acids enhances its survivability, and it is available in both powdered and capsule forms. Although timing with meals has not been extensively evaluated, taking it with meals may aid in absorption.
FAQs
Is *Lactobacillus delbrueckii* subsp. *bulgaricus* safe for everyone?
Generally considered safe, it is recommended to exercise caution in immunocompromised individuals.
When is the best time to take *L. bulgaricus*?
Daily administration is advised, preferably taken with meals to aid in absorption, though timing is not critical.
What results can I expect from taking this probiotic?
Users may experience improvements in lipid profiles and potential antimicrobial benefits, but individual outcomes can vary.
Can it treat diarrhea effectively?
Evidence suggests limited efficacy in treating diarrhea, with some studies showing no significant clinical impact.
Research Sources
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827554/ – This systematic review assessed the effects of probiotics, including Lactobacillus delbrueckii subsp. bulgaricus, on lipid profiles and demonstrated significant improvements in triglycerides and total cholesterol levels among overweight individuals, emphasizing the strain's potential cardiovascular benefits.
- https://pubmed.ncbi.nlm.nih.gov/29203665/ – A randomized controlled trial investigating the antimicrobial effects of Lactobacillus delbrueckii subsp. bulgaricus found it effective against common gastrointestinal pathogens, while highlighting the need for more comprehensive studies on its efficacy against other strains.
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