Lactobacillus Fermentum Mak20l13f
Also known as: *L. fermentum*, probiotic strain, *Lactobacillus fermentum* Mak20l13f
Overview
*Lactobacillus fermentum* Mak20l13f is a strain of lactic acid bacteria found in fermented foods and the human gut, recognized for its probiotic properties. This specific strain is primarily utilized to promote gut health and bolster immune responses. While research on *L. fermentum* generally indicates its effectiveness in modulating gut microbiota, enhancing immune function, and potentially reducing gastrointestinal infections, the body of evidence for the specific strain Mak20l13f remains limited. The research surrounding this strain is at a moderate maturity level, with some randomized controlled trials (RCTs) available, though more extensive studies are needed to elucidate its specific effects and mechanisms. Overall, this strain is generally employed in probiotic supplements aiming to support digestive health.
Benefits
Research shows that *Lactobacillus fermentum* strains can reduce gastrointestinal infections, particularly in infants born by cesarean section. Specifically, *L. fermentum* CECT 5716 has been associated with a significant reduction in these infections, with a reported incidence rate ratio of 0.27 (95% CI, 0.13–0.53). While *L. fermentum* strains might provide immune modulation and gut health benefits, specific evidence supporting *Mak20l13f* remains scarce. The population most likely to benefit appears to be infants at risk for gastrointestinal infections, but the exact benefits and effect sizes for Mak20l13f are still under investigation.
How it works
*Lactobacillus fermentum* Mak20l13f functions by modulating the gut microbiota, thereby enhancing immune responses and potentially interfering with pathogen internalization mechanisms. This strain primarily interacts with the gastrointestinal and immune systems, promoting a beneficial balance of gut bacteria. While precise molecular targets for this specific strain have not been established, probiotics generally exert local effects in the gut rather than systemic absorption.
Side effects
Generally regarded as safe when used as a probiotic, *Lactobacillus fermentum* Mak20l13f may produce mild gastrointestinal effects such as bloating or gas. Serious side effects are rare, though there is a potential risk of infections in individuals with compromised immune systems. Specific adverse effects linked to Mak20l13f are not well-documented. Caution is advised for pregnant or breastfeeding women, as the safety of the strain in these populations has not been thoroughly studied. There is no substantial evidence regarding drug interactions for this specific strain.
Dosage
Currently, there is no established minimum effective dose for *Lactobacillus fermentum* Mak20l13f. Typical probiotic dosages range from 10^8 to 10^10 CFU per day. While specific dosage recommendations for Mak20l13f are not defined, it is suggested that probiotics be taken with food to enhance survival through the gastrointestinal tract. Common forms of administration include capsules and fermented foods, with no known upper safety limits specified. As probiotics exert effects locally in the gut, absorption factors related to bloodstream absorption are not relevant.
FAQs
How should I store probiotics?
Probiotics should be stored in a cool, dry place to maintain their viability and efficacy.
Are probiotics safe for everyone?
While generally safe, individuals who are immunocompromised should consult a healthcare provider before use.
When is the best time to take probiotics?
It is advisable to take probiotics with meals to enhance digestive safety and effectiveness.
What benefits can I expect?
While *Lactobacillus fermentum* may enhance gut health and immune function, specific benefits of Mak20l13f are not well-documented.
Are probiotics a cure-all?
No, probiotics are not a cure-all and their effectiveness can vary among individuals.
Research Sources
- https://www.mdpi.com/2072-6643/11/12/2938 – This meta-analysis reviews the efficacy of various *Lactobacillus* strains, including potential benefits in reducing gastrointestinal symptoms and supporting immune function, while specific findings related to *L. fermentum* Mak20l13f remain limited.
- https://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0178868 – A systematic review highlighting the positive effects of probiotics in managing gastrointestinal health, including the strain *Lactobacillus fermentum*, although the specific impact of Mak20l13f was not detailed.
- https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2022.906924/full – This study focuses on the beneficial outcomes of *Lactobacillus fermentum* CECT 5716 in infants, noting a substantial decrease in infections, which suggests potential implications for other *L. fermentum* strains, yet does not specifically assess Mak20l13f.
- https://pubmed.ncbi.nlm.nih.gov/34208893/ – A comprehensive review examining the lipid-lowering effects of *Lactobacillus* species, demonstrating possible benefits on cholesterol levels, but lacking direct evidence for *L. fermentum* Mak20l13f.
- https://www.jmb.or.kr/journal/view.html?doi=10.4014%2Fjmb.2103.03014 – This academic article conducts a systematic overview of the effects of probiotics on health, providing insights into *Lactobacillus* strains while not specifically addressing the Mak20l13f strain.
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