Lactobacillus Helveticus R0419nd
Also known as: Lactobacillus helveticus R0419, Probiotic Lactobacillus helveticus, Lactobacillus helveticus probiotic strain, Lactobacillus helveticus
Overview
*Lactobacillus helveticus* is a species of lactic acid bacteria primarily found in fermented dairy products such as yogurt and cheese, as well as the human gastrointestinal tract. As a recognized probiotic, it plays a significant role in supporting gut health, boosting the immune system, and improving various metabolic parameters. This strain exhibits high resilience, allowing it to endure the harsh acidic environments of the stomach and intestines, thereby positively influencing gut microbiota composition. Notably, numerous systematic reviews and randomized controlled trials affirm the efficacy and safety of *Lactobacillus helveticus*, demonstrating its influence on cardiovascular health and metabolic functions. Supplementation is commonly available in forms including capsules, powders, and tablets, catering to diverse consumer preferences and accessibility.
Benefits
Studies emphasize the cholesterol-lowering effects of *Lactobacillus helveticus*, particularly in overweight and obese individuals. A meta-analysis reported a mean reduction in low-density lipoprotein (LDL) cholesterol by 5.27 mg/dL and total cholesterol by 4.84 mg/dL, with statistically significant p-values (0.0006 for LDL and 0.006 for total cholesterol). Additionally, it has been observed to lower fasting plasma glucose and triglyceride levels by 1.81 mg/dL and 14.14 mg/dL, respectively. The benefits of this probiotic are particularly pronounced in populations facing dyslipidemia and those managing elevated blood glucose levels, indicating a significant role in metabolic health.
How it works
*Lactobacillus helveticus* operates by modulating the gut microbiota, promoting a balanced microbial environment. It fosters the production of short-chain fatty acids, which are crucial for maintaining gut health and facilitating metabolic processes. Furthermore, this strain may enhance interconnections between the gut and brain through the synthesis of gamma-aminobutyric acid (GABA), potentially impacting mood and reducing anxiety. Its remarkable survival rate during gastrointestinal transit (exceeding 77% in various studies) further underscores its efficacy as a probiotic.
Side effects
Overall, *Lactobacillus helveticus* is considered safe for consumption, with minimal adverse effects reported in clinical studies. Common side effects are rare, occurring in less than 5% of users, and may include mild gastrointestinal discomfort, such as bloating or gas. Notably, no severe side effects have been documented. While the risk of drug interactions appears low, caution is warranted for individuals who are severely immunocompromised or pregnant/nursing; such individuals should consult their healthcare provider for personalized recommendations. The existing literature supports a strong safety profile for this probiotic strain, with no significant adverse events recorded.
Dosage
Recommended dosages for *Lactobacillus helveticus* generally fall within the range of 1 x 10^10 to 3 x 10^10 colony-forming units (CFU) per day. The threshold for demonstrated effectiveness begins at 1 x 10^10 CFU, with studies indicating that clinical benefits may manifest after approximately 12 weeks of consistent supplementation. Although no upper limit is specifically established for safety, it is prudent to adhere to dosages utilized in clinical research unless advised otherwise by a healthcare professional. The supplement can be taken at any time of day; however, regular daily intake may optimize health benefits, regardless of whether it is in capsule or powder form.
FAQs
Is *Lactobacillus helveticus* safe?
Yes, it is generally considered safe, but individuals with severe immunocompromise should seek medical advice before use.
When should I take it?
Timing is flexible, but consistent daily intake is recommended for optimal benefits.
How long until I see results?
Expect improvements in cholesterol and glucose levels after approximately 12 weeks of supplementation.
Are there any misconceptions about probiotics?
Probiotics have variable effects on individuals and are not a universal solution for all health issues.
Research Sources
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607232/ – This systematic review evaluated the effects of various probiotic strains, including *Lactobacillus helveticus*, on lipid profiles and glucose metabolism, highlighting its significant impact on reducing cholesterol and triglyceride levels in specific populations. The rigorous methodology included randomized controlled trials providing strong evidence for its efficacy.
- https://pubmed.ncbi.nlm.nih.gov/30328270/ – In this meta-analysis, authors examined the impact of *Lactobacillus helveticus* on dyslipidemia and glucose control among adults, demonstrating statistically significant reductions in LDL and total cholesterol parameters. They emphasized the effectiveness in overweight and obese populations.
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