Lactobacillus Rhamnosus B
Also known as: Lactobacillus rhamnosus GG, Probiotic bacteria, Lactobacillus rhamnosus
Overview
*Lactobacillus rhamnosus* is a species of beneficial lactic acid bacteria commonly found in fermented foods and the human gut microbiota. It is primarily utilized as a probiotic supplement for gastrointestinal health, immune system modulation, and prevention of certain infections. Notably, the strain *L. rhamnosus* GG has been extensively researched and recognized for its ability to adhere to intestinal epithelial cells, contributing to overall gut health and immunity. The research on this strain is robust, marked by high-quality evidence, including systematic reviews and meta-analyses that highlight various health benefits.
Benefits
The benefits of *Lactobacillus rhamnosus* GG include: 1) Enhancement of tolerance to cow's milk in allergic children (RR 2.22), 2) Reduction in crying time in infants with colic by approximately 32.59 minutes daily, and 3) Prevention of antibiotic-associated diarrhea among children. These findings suggest specific efficacy in pediatric populations, particularly in managing cow's milk allergy and colic. The evidence supporting these benefits is credible, stemming from well-designed studies demonstrating significant improvements in targeted health outcomes within weeks of treatment.
How it works
*Lactobacillus rhamnosus* primarily functions by modulating gut microbiota, enhancing intestinal barrier function, and interacting with immune responses. It influences cytokine production and immune cell activity, contributing to improved immune modulation and gut health. This strain effectively colonizes the gut, improving overall gut flora balance, and is known for its strong adhesion abilities to intestinal cells, factors that bolster its beneficial effects on health.
Side effects
Generally, *Lactobacillus rhamnosus* is considered safe with few reported side effects. Common mild side effects may include gastrointestinal symptoms like bloating or gas, occurring in less than 5% of users. Serious adverse effects are rare (<1%), and there are no significant drug interactions documented. However, caution is advised for immunocompromised individuals as probiotics could potentially lead to infections in these populations. Specific contra-indications are limited, but individuals with compromised immune systems should consult healthcare professionals prior to use. Overall, it has a favorable safety profile across all age groups.
Dosage
The typical recommended dosage of *Lactobacillus rhamnosus* ranges from 1 to 10 billion CFU (colony-forming units) per day, which is effective for most applications. It is best administered with food to enhance its survival through the stomach, maximizing probiotic effectiveness. While higher doses are generally well tolerated, any significant increase in dosage should be discussed with a healthcare provider to ensure individual safety. Forms of administration include capsules, powders, and dietary sources such as fermented foods.
FAQs
How should I store Lactobacillus rhamnosus supplements?
Store in a cool, dry place, and ensure proper sealing to maintain probiotic viability.
Is Lactobacillus rhamnosus safe for children?
Yes, it is generally safe for children, but consult a healthcare provider for specific conditions.
When is the best time to take it?
It is best taken with meals to enhance gut survival.
How long does it take to see results?
Benefits are often observed within weeks of consistent use.
Can Lactobacillus rhamnosus cure gastrointestinal issues?
It is not a cure-all; benefits can vary based on individual health conditions.
Research Sources
- https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2021.727127/full – This meta-analysis of 565 children with cow's milk allergy concludes that *L. rhamnosus* GG enhances tolerance, suggesting significant clinical relevance. Limitations noted include a lack of long-term effect data.
- https://pubmed.ncbi.nlm.nih.gov/39263298/ – Research focusing on infant colic shows that *L. rhamnosus* GG significantly diminishes daily crying time among infants, indicating therapeutic potential in pediatric gastrointestinal distress.
- https://www.ncbi.nlm.nih.gov/books/NBK85076/ – This systematic review found *L. rhamnosus* GG effective in reducing the incidence of healthcare-associated diarrhea in a sample of 1092 children, underscoring its protective role in vulnerable populations.
- https://pubmed.ncbi.nlm.nih.gov/26365389/ – The research provides evidence of *L. rhamnosus* GG's efficacy in preventing antibiotic-associated diarrhea in children, supporting its use as a preventative strategy during antibiotic treatment.
- https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2018.00124/full – This source emphasizes the multiple roles of probiotics, including *L. rhamnosus*, in promoting gut health, highlighting mechanisms and implications for therapeutic applications.
Supplements Containing Lactobacillus Rhamnosus B
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