Lactospore Lactobacillus Sporogenes
Also known as: LactoSpore, Lactobacillus Sporogenes (misnomer), Bacillus coagulans
Overview
*Bacillus coagulans* is a spore-forming, lactic acid-producing bacterium widely utilized as a probiotic supplement. Despite often being misidentified as *Lactobacillus Sporogenes*, it belongs to the *Bacillus* genus. Its spore-forming ability confers high resistance to heat and gastric acidity, allowing it to survive passage through the stomach and reach the intestines intact. It is naturally found in soil and is incorporated into various food products and supplements to promote gut health. Research indicates its potential in alleviating gastrointestinal symptoms and maintaining a balanced gut microbiota. Available in forms like capsules and powders, *Bacillus coagulans* is generally recognized as safe and effective for improving digestive wellness.
Benefits
*Bacillus coagulans* has demonstrated efficacy in reducing gastrointestinal symptoms such as gas and bloating in healthy adults. A randomized controlled trial (RCT) showed a significant reduction in GSRS indigestion scores (P < 0.001) within a few weeks of supplementation, indicating its potential to alleviate discomfort associated with indigestion. Furthermore, *Bacillus coagulans* may contribute to improved gut health by maintaining a balance of beneficial bacteria. While some studies suggest it does not significantly alter the gut microbiome in healthy individuals, its lactic acid production can create a favorable environment for other beneficial bacteria to thrive. These benefits are particularly relevant for adults experiencing functional gas and bloating, offering a natural approach to managing digestive discomfort.
How it works
*Bacillus coagulans* exerts its probiotic effects primarily through modulation of the gut microbiota and improvement of digestion. As a spore-forming bacterium, it survives the acidic environment of the stomach, reaching the intestines where it germinates and becomes metabolically active. Once active, it produces lactic acid, which helps to create an environment that inhibits the growth of pathogenic bacteria and promotes the growth of beneficial bacteria. While the precise molecular targets are not fully defined, *Bacillus coagulans* influences the composition of the gut flora, contributing to a healthier digestive system.
Side effects
*Bacillus coagulans* is generally recognized as safe (GRAS) by the FDA and is well-tolerated by most individuals. Common side effects are rarely reported, indicating a high safety profile. Uncommon and rare side effects are not well-documented in available literature. No significant drug interactions or contraindications have been reported. It is considered safe for healthy adults, but data on other populations, such as pregnant women or individuals with compromised immune systems, is limited. While generally safe, it is always advisable to consult with a healthcare provider before starting any new supplement, especially for individuals with underlying health conditions.
Dosage
The minimum effective dose of *Bacillus coagulans* is 2 billion CFU/day, with optimal dosage ranges typically between 1-2 billion CFU/day. While the maximum safe dose is not well-defined, high doses are generally well-tolerated. There are no specific timing recommendations for taking *Bacillus coagulans*; it can be taken with or without food. It is available in various forms, including capsules and powders. The spore form of *Bacillus coagulans* enhances its survival through the digestive system, ensuring that a higher percentage of the bacteria reach the intestines. No required cofactors have been documented for its efficacy.
FAQs
Is *Bacillus coagulans* safe to use?
Yes, *Bacillus coagulans* is generally recognized as safe (GRAS) by the FDA. However, it's always best to consult with a healthcare provider before starting any new supplement.
When is the best time to take *Bacillus coagulans*?
There are no specific timing recommendations. It can be taken with or without food, whenever is most convenient for you.
How long does it take to see results?
You may start to see a reduction in gastrointestinal symptoms, such as gas and bloating, within a few weeks of consistent supplementation.
Is *Bacillus coagulans* the same as *Lactobacillus Sporogenes*?
No, *Bacillus coagulans* is often misidentified as *Lactobacillus Sporogenes*, but it is a distinct species belonging to the *Bacillus* genus.
What is the recommended dosage?
The recommended dosage is typically 1-2 billion CFU per day. Some studies have used 2 billion CFU/day effectively.
Research Sources
- https://www.fda.gov/files/food/published/GRAS-Notice-000601---Bacillus-coagulans-SBC37-01-spore-preparation.pdf – This GRAS (Generally Recognized as Safe) notification to the FDA confirms the safety of *Bacillus coagulans* SBC37-01 spore preparation for use in food. The assessment concludes that *Bacillus coagulans* is safe under the intended conditions of use, supporting its use as a probiotic ingredient in various food products.
- https://pubmed.ncbi.nlm.nih.gov/36862903/ – This randomized controlled trial (RCT) with 70 adults found that *Bacillus coagulans* significantly reduced gastrointestinal symptoms. The study highlights the potential of *Bacillus coagulans* in alleviating discomfort associated with indigestion, as evidenced by a significant reduction in GSRS indigestion scores (P < 0.001).
- https://journals.lww.com/md-journal/fulltext/2023/05190/probiotic_modulation_of_gut_microbiota_by_bacillus.53.aspx – This RCT involving 30 adults examined the impact of *Bacillus coagulans* on gut microbiota. The study found no significant alteration of the gut microbiome in healthy individuals, suggesting that while *Bacillus coagulans* may not drastically change the overall composition, it can still contribute to gut health through other mechanisms.
- https://pubmed.ncbi.nlm.nih.gov/12197786/ – This study investigates the effects of *Bacillus coagulans* on irritable bowel syndrome (IBS) symptoms. While the abstract provides limited details, the research suggests a potential role for *Bacillus coagulans* in managing IBS-related discomfort.
- https://www.frontiersin.org/journals/pediatrics/articles/10.3389/fped.2023.1338126/full – This article reviews the use of probiotics, including *Bacillus coagulans*, in pediatric populations. It discusses the potential benefits of probiotics in managing various gastrointestinal conditions in children, highlighting the importance of strain-specific research to determine efficacy and safety.
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