Lemon Myrtle Leaf Oil
Also known as: Lemon Myrtle, Sweet Verbena Tree, *Backhousia citriodora*
Overview
Lemon Myrtle Leaf Oil is an essential oil derived from the leaves of *Backhousia citriodora*, a plant native to Australia. Known for its strong citrus aroma, this oil has been traditionally utilized in folk medicine for its potential health benefits, such as treating wounds, cancers, and skin infections. Its primary active component, citral, confers antimicrobial and anti-inflammatory properties. Although promising emerging research highlights its anti-cancer and anti-diabetic activities, particularly in vitro and in animal studies, evidence from high-quality human clinical trials is still limited. Traditionally, Lemon Myrtle Oil is used in aromatherapy and can be applied topically in diluted form, emphasizing its rich historical and cultural importance in natural healing practices.
Benefits
Research indicates that Lemon Myrtle Leaf Oil may exhibit several notable benefits, particularly related to its anti-cancer and anti-diabetic properties. In vitro studies have demonstrated significant cytotoxic effects against various cancer cell lines, including liver, neuroblastoma, colon, and lung cancer cells, with mechanisms likely involving cell cycle arrest and apoptosis induction via molecular targets like p53. Additionally, some evidence points toward its potential to modulate glucose metabolism pathways, offering benefits for managing diabetes. However, documented clinical trials in humans are sparse, necessitating further research to validate these findings and determine their clinical significance.
How it works
The anti-cancer properties of Lemon Myrtle Leaf Oil are believed to be mediated through cell cycle arrest and the induction of apoptosis, particularly via p53 pathway signaling. Its anti-diabetic effects may involve modulation of various biological pathways, including AMP-activated protein kinase (AMPK) and glucose transporter type 4 (GLUT4), which plays a crucial role in glucose metabolism. Interaction with other targets, like androgen receptors and cyclin-dependent kinases, further contributes to its potential health benefits, although specific mechanisms in humans are yet to be elucidated.
Side effects
Lemon Myrtle Leaf Oil is generally considered safe when used appropriately; however, comprehensive safety data in humans remains limited. Due to the lack of extensive human clinical trials, common side effects are not well-documented, though essential oils can induce skin irritation or allergic reactions, especially if applied undiluted or to sensitive areas. Rare side effects have not been established. Caution is advised for individuals who are pregnant, breastfeeding, or have sensitive skin. Moreover, drug interactions have not been studied extensively, reinforcing the need for careful usage and consultation with a healthcare provider for individuals on concurrent medications.
Dosage
Currently, there are no established minimum effective doses or optimal dosage ranges for Lemon Myrtle Leaf Oil in humans based on clinical evidence. The safety and efficacy of the oil depend significantly on its form; it is typically used in aromatherapy or for topical applications in a diluted state. Due to the lack of clarity on maximum safe doses and timing for specific health benefits, it is recommended to apply the oil with caution, ensuring it is well-diluted in a carrier oil for topical use. Further research is essential to determine proper dosing guidelines and safety thresholds.
FAQs
How should I use Lemon Myrtle Leaf Oil?
Use it in well-ventilated areas and always dilute with a carrier oil for topical applications to prevent irritation.
Is it safe to ingest Lemon Myrtle Leaf Oil?
Ingestion is not advisable as safety data is insufficient; focus on aromatherapy and topical use instead.
What effects can I expect from using Lemon Myrtle Leaf Oil?
Potential benefits may include anti-cancer and anti-diabetic effects, but these claims need more human research to support.
Can Lemon Myrtle Leaf Oil cause allergies?
Yes, it may cause skin irritation or allergic reactions; it's crucial to perform a patch test before extensive use.
Are there any known drug interactions?
Currently, potential drug interactions are unknown due to limited human studies; consult with a healthcare provider if needed.
Research Sources
- https://www.hsrd.research.va.gov/publications/esp/aromatherapy.pdf – This systematic review synthesizes evidence on the efficacy of various essential oils in therapeutic settings, highlighting the necessity for further research to establish stronger clinical guidelines.
- https://pubmed.ncbi.nlm.nih.gov/37054823/ – Research shows that Lemon Myrtle Essential Oil displays cytotoxic properties against several cancer cell lines, indicating its potential as a natural anti-cancer agent, but human data is still warranted.
- https://oar.a-star.edu.sg/storage/2/2rxkegpk5k/bfsn2170320-au.pdf – A systematic review investigating various essential oils found those with citral may positively impact glucose metabolism, suggesting potential benefits for managing diabetes; clinical evidence is needed.
- https://pubmed.ncbi.nlm.nih.gov/37960098/ – This in vitro study assesses the anti-cancer effects of Lemon Myrtle and shows promising results against multiple cancer types, although further research is required to confirm these effects in humans.
- https://www.researchgate.net/publication/364504127_Phytochemicals_and_Bioactivities_of_Australian_Native_Lemon_Myrtle_Backhousia_citriodora_and_Lemon-Scented_Tea_Tree_Leptospermum_petersonii_A_Comprehensive_Review – A comprehensive review examining the phytochemicals and bioactivities of Lemon Myrtle, detailing its potential therapeutic applications and emphasizing the need for additional human clinical trials.