Leucoselect Phytosome
Also known as: Grape seed extract, Oligomeric proanthocyanidins (OPCs), Vitis vinifera extract, Leucoselect Phytosome
Overview
Leucoselect Phytosome is a standardized grape seed extract derived from *Vitis vinifera* L. seeds, combined with soy lecithin to enhance its bioavailability through the Indena Phytosome delivery system. It features a high concentration of oligomeric proanthocyanidins (OPCs), specifically standardized to 25-36% proanthocyanidins, making it a potent antioxidant supplement. Commonly used for supporting cardiovascular health, enhancing antioxidant capacity, and improving immune function, Leucoselect Phytosome is recognized for its ability to scavenge free radicals and reduce oxidative stress. The research surrounding its efficacy is of moderate maturity, with various human studies indicating positive outcomes, although more rigorous systematic reviews are necessary for definitive conclusions.
Benefits
Leucoselect Phytosome demonstrates several evidence-based benefits. Notably, it improves the total antioxidant capacity of plasma and decreases LDL susceptibility to oxidative stress, particularly in heavy smokers. Additionally, its supplementation may enhance immune function and overall life quality in elderly populations. While specific effect sizes and clinical significance are not well-documented, certain populations, such as individuals facing impaired glucose homeostasis and the elderly, appear to benefit most from its antioxidant properties. However, the body of research is varied, and comprehensive analysis through broader studies is essential to verify these benefits.
How it works
Leucoselect Phytosome exerts its effects primarily through antioxidant activity, actively scavenging free radicals and protecting cellular structures from oxidative damage. It interacts significantly with the cardiovascular and immune systems, supporting overall health. The Indena Phytosome delivery system enhances the absorption and bioavailability of proanthocyanidins, allowing for more effective utilization within the body, although specific molecular targets remain unspecified in the literature.
Side effects
Leucoselect Phytosome is generally regarded as safe, although detailed safety data is limited. Common side effects are not well-documented, and severe adverse effects are rare. Potential interactions with anticoagulants may occur due to its antioxidant effects, necessitating caution in individuals taking blood thinning medications. There are no specific contraindications identified, but pregnant and lactating women should exercise caution due to insufficient safety data in these populations. Overall, while the safety profile appears favorable, the lack of comprehensive data emphasizes the need for careful use.
Dosage
The minimum effective dose for Leucoselect Phytosome is generally considered to be 300 mg per day; however, optimal dosage ranges are not well-established. There are currently no maximum safe dose guidelines documented. Timing of consumption does not have specific recommendations. The Phytosome formulation is emphasized for its enhanced bioavailability, primarily due to the soy lecithin component. Factors such as absorption rates and interactions with other compounds are noted, but specific cofactors required for effectiveness have not been identified.
FAQs
Is Leucoselect Phytosome safe to use?
Generally considered safe, but comprehensive safety data is lacking. Consult a healthcare provider if pregnant or nursing.
Can Leucoselect Phytosome interact with other medications?
Yes, it may interact with anticoagulants due to its antioxidant properties. Caution is advised.
When should I take Leucoselect Phytosome?
No specific timing is recommended; however, taking it consistently may enhance its benefits.
What benefits can I expect from taking Leucoselect Phytosome?
Expected benefits include improved antioxidant capacity and support for cardiovascular health.
Are there any common misconceptions about Leucoselect Phytosome?
There is limited documentation on misconceptions, but it is crucial to rely on credible research regarding its efficacy.
Research Sources
- https://www.indena.com/us/product/leucoselect-phytosome/ – Indena's official page on Leucoselect Phytosome outlines its formulation, mechanisms, and research summaries, supporting its antioxidant and health benefits.
- https://ueaeprints.uea.ac.uk/id/eprint/48108/1/Besim_Ozyel.pdf – This study discusses the potential health benefits and antioxidant effects of grape seed extract, noting improvements in plasma antioxidant levels.
- https://www.researchgate.net/publication/379455055_The_Lipid-Lowering_Efficacy_of_a_Nutraceutical_Combination_Including_Leucoselect_Phytosome_Red_Yeast_Rice_Policosanol_and_Folic_Acid_in_Dyslipidaemia_Patients_Real-World_Insights – This research investigates the lipid-lowering effects of a combination therapy including Leucoselect Phytosome, demonstrating its potential in managing dyslipidemia.
- https://ouci.dntb.gov.ua/en/works/7BoA8y64/ – The paper reviews various dietary interventions, including grape seed extract, highlighting its role in improving oxidative stress markers.
- https://uxbeauty.givaudan.com/ingredients/permalink/givaudan-leucoselect-phytosome – Givaudan's ingredient profile on Leucoselect Phytosome outlines its benefits and applications in promoting skin health and overall wellness.
