Get Your Personalized Supplement StackSupplement Stack Quiz

Long Jack

Also known as: Eurycoma longifolia Jack, Longjack, Tongkat Ali, Eurycoma longifolia

Overview

Eurycoma longifolia, commonly known as Longjack or Tongkat Ali, is a plant native to Southeast Asia, where it has been traditionally used for its medicinal properties. The active compounds are primarily extracted from the roots of the plant. Historically, it has been used to treat fevers and bacterial infections, and as an aphrodisiac. Modern applications focus on its potential to enhance male fertility, alleviate stress, and boost testosterone levels. Longjack contains various bioactive compounds, including quassinoids, alkaloids, and flavonoids, which are believed to contribute to its purported health benefits. While research is ongoing, the current evidence base is considered emerging and somewhat limited, with many studies exhibiting methodological constraints. Despite these limitations, systematic reviews and meta-analyses suggest potential benefits, particularly in testosterone enhancement, warranting further investigation.

Benefits

Longjack has shown potential benefits in several areas, primarily related to male health. A systematic review and meta-analysis indicated a significant increase in total testosterone levels in men who supplemented with Eurycoma longifolia (SMD = 1.352, 95% CI 0.565 to 2.138, p = 0.001). This effect may be particularly beneficial for men with hypogonadism. Some studies also suggest that Longjack may reduce stress hormones and improve mood, although the evidence is less robust. Additionally, there is emerging evidence suggesting potential benefits for male fertility, specifically in improving sperm concentration and morphology. However, these findings are based on studies with limitations, such as small sample sizes or lack of randomization, necessitating further research to confirm these effects.

How it works

Longjack's mechanism of action is thought to involve the bioactive compounds it contains, such as quassinoids, which may influence hormone regulation and stress response pathways. It is believed to interact with the endocrine system to enhance testosterone production and with the nervous system to reduce stress. While the precise molecular targets are not fully defined, it may involve modulation of hormone receptors and stress-related neurotransmitters. Longjack is typically consumed as a water or alcohol-based extract, but limited data exists regarding its absorption and bioavailability.

Side effects

Longjack is generally considered safe for short-term use at typical doses, but comprehensive long-term safety data are lacking. Common side effects are not well-documented due to limited research. Uncommon side effects may include potential interactions with certain medications, such as propranolol. Rare side effects are currently undetermined due to insufficient data. Caution is advised when using Longjack with propranolol and potentially with hypoglycemic agents. It is contraindicated in children, pregnant, and breastfeeding women due to insufficient safety data. Individuals with weakened immune systems or certain medical conditions, such as heart disease, should use Longjack with caution.

Dosage

The minimum effective dose of Longjack typically ranges from 200 mg to 400 mg per day. Most studies have used doses between 200 mg and 300 mg daily. The maximum safe dose is not well-established, but doses up to 400 mg per day have been used without reported adverse effects in studies. There are no specific timing recommendations available. Longjack is often consumed as a water or alcohol-based extract. Limited data is available on factors affecting absorption. No required cofactors have been identified. It is important to consult with a healthcare provider before starting Longjack supplementation to determine the appropriate dosage and ensure safety.

FAQs

Is Longjack safe to use?

Longjack is generally considered safe for short-term use at recommended doses. However, long-term safety data are lacking, and it should be avoided by children, pregnant, and breastfeeding women.

How should I take Longjack?

Longjack is typically consumed as a water or alcohol-based extract. While specific timing isn't crucial, consistency is key. Consult with a healthcare provider for personalized advice.

What are the expected benefits of Longjack?

Potential benefits include enhanced testosterone levels and stress relief. However, individual results may vary, and it is not a proven treatment for erectile dysfunction or a guaranteed performance enhancer.

Are there any drug interactions I should be aware of?

Caution is advised when using Longjack with certain medications, such as propranolol and potentially with hypoglycemic agents. Consult with a healthcare provider to avoid potential interactions.

Who should avoid taking Longjack?

Children, pregnant, and breastfeeding women should avoid Longjack due to insufficient safety data. Individuals with weakened immune systems or certain medical conditions like heart disease should use it with caution.

Research Sources

https://www.mdpi.com/2076-3417/14/11/4372 – This systematic review and meta-analysis examined the effects of Eurycoma longifolia supplementation on testosterone levels in men. The analysis of nine studies revealed a significant increase in total testosterone levels, suggesting a potential benefit for men, particularly those with hypogonadism. However, the authors noted limitations due to small sample sizes and methodological issues in some of the included studies, highlighting the need for more robust research.
https://pubmed.ncbi.nlm.nih.gov/23419023/ – This randomized, controlled trial investigated the effects of Tongkat Ali on stress hormones and mood in 63 adults with moderate stress. The study found that supplementation with Tongkat Ali led to a reduction in stress hormones and an improvement in mood. While the results suggest potential benefits for stress relief, the study's small sample size and limited duration call for further validation through larger, longer-term trials.
https://www.publish.csiro.au/hc/pdf/HC22143 – This paper discusses the traditional uses, phytochemistry, and bioactivity of Eurycoma longifolia. It highlights the presence of bioactive compounds like quassinoids, alkaloids, and flavonoids, which are believed to contribute to its medicinal properties. The review also touches upon the potential benefits for male fertility and athletic performance, while emphasizing the need for more comprehensive research to fully understand its mechanisms and effects.
https://pubmed.ncbi.nlm.nih.gov/36013514/ – This study investigated the effects of Eurycoma longifolia extract on various health parameters. The findings suggest potential benefits in improving sperm concentration and morphology in men with idiopathic male infertility. However, the study's lack of randomization and a control group limits the strength of the conclusions, indicating a need for more rigorous, controlled trials to confirm these fertility benefits.
https://www.healthline.com/nutrition/tongkat-ali-longjack-review – This review provides an overview of Tongkat Ali, discussing its potential benefits, side effects, and dosage. It highlights the traditional uses of the plant and its modern applications, particularly in enhancing male fertility and boosting testosterone levels. The review also emphasizes the importance of consulting with a healthcare professional before using Tongkat Ali, especially for individuals with pre-existing medical conditions or those taking medications.