Longjack
Also known as: Eurycoma longifolia Jack, Longjack, Tongkat Ali, Eurycoma longifolia
Overview
Eurycoma longifolia, commonly known as Longjack or Tongkat Ali, is a medicinal plant native to Southeast Asia. It has been traditionally used for various ailments, including fevers and bacterial infections, and as an aphrodisiac. The plant's roots are the primary source of its bioactive compounds, which include quassinoids, alkaloids, and flavonoids. Modern research focuses on its potential benefits for male fertility, stress relief, and testosterone enhancement. While emerging research shows promise, the evidence is still limited, with many studies having methodological limitations. Longjack is typically consumed as a water or alcohol-based extract. Systematic reviews and meta-analyses suggest potential benefits, but more robust studies are needed to confirm these findings.
Benefits
Longjack has shown potential benefits in several areas, primarily related to testosterone enhancement and stress relief. A systematic review and meta-analysis indicated a significant increase in total testosterone levels in men (SMD = 1.352, 95% CI 0.565 to 2.138, *p* = 0.001). Some studies also suggest that Longjack may reduce stress hormones and improve mood, although the evidence is limited. Additionally, there is potential for benefits in male fertility and athletic performance, but further research is necessary to validate these effects. The testosterone enhancement effect may be particularly beneficial for hypogonadal men. Most studies have short durations, typically ranging from a few weeks to months.
How it works
The bioactive compounds in Longjack, such as quassinoids, are believed to influence hormone regulation and stress response pathways. It may interact with the endocrine system to enhance testosterone production and with the nervous system to reduce stress. While the exact molecular targets are not well-defined, Longjack may modulate hormone receptors and stress-related neurotransmitters. It is generally consumed as a water or alcohol-based extract, but limited data exists on its absorption and bioavailability. Further research is needed to fully elucidate the mechanisms of action.
Side effects
Longjack is generally considered safe for short-term use at typical doses, but long-term safety data are lacking. Common side effects are not well-documented due to limited research. Uncommon side effects may include potential interactions with certain medications, such as propranolol. Rare side effects are not well-defined due to insufficient data. Caution is advised when using Longjack with propranolol and potentially with hypoglycemic agents. It should be avoided in children, pregnant, and breastfeeding women due to insufficient safety data. Individuals with weakened immune systems or certain medical conditions like heart disease should use it with caution.
Dosage
The minimum effective dose of Longjack typically ranges from 200 mg to 400 mg per day. Most studies use doses between 200 mg and 300 mg daily. The maximum safe dose is not well-established, but doses up to 400 mg per day have been used without reported adverse effects. There are no specific timing recommendations available. It is often consumed as a water or alcohol-based extract. Limited data exists on factors affecting absorption. No required cofactors have been identified. It is important to consult with a healthcare provider before starting Longjack supplementation.
FAQs
Is Longjack safe to use?
Longjack is generally safe for short-term use at recommended doses. However, long-term safety data are lacking. Consult a healthcare provider before use, especially if you have medical conditions or are taking medications.
What are the expected benefits of Longjack?
Potential benefits include testosterone enhancement and stress relief. Individual results may vary. It is not a proven treatment for erectile dysfunction or a guaranteed performance enhancer.
How should I take Longjack?
Typical dosages range from 200 mg to 400 mg per day. There are no specific timing recommendations. It is often consumed as a water or alcohol-based extract. Consult your healthcare provider for personalized advice.
Are there any contraindications for Longjack?
Longjack should be avoided in children, pregnant, and breastfeeding women due to insufficient safety data. Use with caution in individuals with weakened immune systems or certain medical conditions like heart disease.
Can Longjack interact with medications?
Yes, Longjack may interact with certain medications, such as propranolol and potentially with hypoglycemic agents. Consult your healthcare provider to discuss potential interactions.
Research Sources
- https://www.mdpi.com/2076-3417/14/11/4372 – This systematic review and meta-analysis examined the effects of *Eurycoma longifolia* supplementation on testosterone levels in men. The review included nine studies and found a significant increase in total testosterone levels. The authors noted that the evidence is limited by small sample sizes and methodological issues in some studies, highlighting the need for more robust research.
- https://pubmed.ncbi.nlm.nih.gov/23419023/ – This randomized, placebo-controlled, parallel group study investigated the effects of a standardized *Eurycoma longifolia* extract on stress hormones and mood state in 63 subjects with moderate stress. The study found that supplementation with *Eurycoma longifolia* significantly reduced stress hormones and improved certain mood state parameters. However, the small sample size and limited duration suggest the need for further validation.
- https://www.publish.csiro.au/hc/pdf/HC22143 – This paper discusses the traditional uses, phytochemistry, and bioactivity of *Eurycoma longifolia*. It highlights the plant's use in traditional medicine for various ailments and discusses the bioactive compounds responsible for its effects. The review also touches on potential drug interactions, specifically with propranolol, and advises caution in individuals with weakened immune systems or heart disease.
- https://pubmed.ncbi.nlm.nih.gov/36013514/ – This study investigated the effects of *Eurycoma longifolia* on sperm parameters in men with idiopathic infertility. The open study, involving 350 men over 9 months, reported improvements in sperm concentration and morphology. However, the lack of randomization and a control group limits the strength of the conclusions regarding fertility benefits.
- https://www.healthline.com/nutrition/tongkat-ali-longjack-review – This is a general review article on Tongkat Ali (Longjack), summarizing its potential benefits, uses, and side effects. It provides an overview of the existing research and highlights the need for more high-quality studies to confirm its efficacy and safety. The article also cautions against using Longjack during pregnancy and breastfeeding.
