Lycium Barbarum Fruit Extract
Also known as: Goji berry, Wolfberry, Lycium barbarum
Overview
Lycium barbarum, commonly known as goji berry or wolfberry, is a plant native to East Asia. It is widely recognized for its historical use in traditional medicine and is increasingly acknowledged for its health benefits. The fruit is rich in bioactive compounds, including polysaccharides, carotenoids, and flavonoids, which contribute to its health-promoting properties. *L. barbarum* is primarily utilized for its immune-modulating and antioxidant effects, along with potential benefits for metabolic and cardiovascular health. While a growing body of evidence from clinical trials supports these effects, the overall research quality varies, and further long-term studies are necessary to establish definitive benefits.
Benefits
1. **Immune Modulation**: Research indicates *L. barbarum* can enhance immune function by increasing lymphocyte counts and cytokine levels, particularly beneficial for the elderly. 2. **Antioxidant Effects**: It exhibits strong antioxidant properties that may protect against oxidative stress-related diseases, contributing to overall cellular health. 3. **Metabolic Health**: Some studies suggest potential improvements in lipid metabolism and body weight management, showing promise for individuals with metabolic disorders. 4. **Cardiovascular Health**: Evidence regarding its ability to regulate lipid profiles is mixed but indicates potential benefits with further investigation required. Overall, while some studies demonstrate significant results, the variability in effect sizes calls for further rigorous trials for confirmation.
How it works
The primary mechanism of action of *Lycium barbarum* involves enhancing immune function through increased lymphocyte counts and cytokine production. It also neutralizes free radicals, thereby reducing oxidative stress within the body. Key interactions include enzymatic hydrolysis of polysaccharides in the digestive system, leading to absorption into the bloodstream, where bioactive compounds exert their effects. Additionally, *L. barbarum* modulates inflammatory pathways through its anti-inflammatory properties and has targeted benefits in combating oxidative stress.
Side effects
Overall, *Lycium barbarum* is considered safe when consumed in moderation. Common side effects may include mild gastrointestinal discomfort, such as stomach upset, occurring in over 5% of users. Uncommon side effects (1-5%) might involve allergic reactions in individuals sensitive to plants in the Solanaceae family, while rare side effects (<1%) may include hypersensitivity reactions. Caution is advised regarding potential interactions with medications, particularly blood thinners due to its antioxidant effects, and diabetes medications as it may affect blood sugar levels. It is contraindicated during pregnancy and breastfeeding due to limited data and should be avoided if there is a known allergy to related plants.
Dosage
The recommended minimum effective dose of *L. barbarum* varies based on form: juice at 120 mL/day or extract ranging from 300 mg to 1 g per day is commonly used in studies. For general health, dosages between 300 mg and 1 g daily are suggested, with specific conditions potentially requiring adjusted amounts. While the maximum safe dose is not well-defined, it is advisable to limit intake to below 1 g per day. Timing plays a role in absorption; taking it with meals may enhance uptake. Consistent daily intake is encouraged for best results, and bioavailability can be improved with certain formulations, like homogenized milk.
FAQs
Is Lycium barbarum safe for long-term use?
Generally considered safe, but long-term studies are limited.
Can it interact with medications?
Yes, potential interactions with blood thinners and diabetes medications exist.
What are the best forms to consume?
Juice and extracts are common; bioavailability may vary by formulation.
How quickly can benefits be observed?
Benefits can be seen within days to weeks, depending on the health outcome.
Are there any known side effects?
Generally mild gastrointestinal discomfort; rare allergic reactions may occur.
Research Sources
- https://journals.lww.com/md-journal/fulltext/2021/12100/efficacy_of_lycium_barbarum_l__on_plasma_lipid.73.aspx – This study evaluated the efficacy of *Lycium barbarum* on plasma lipid concentrations, demonstrating potential benefits in lipid management although results are pending.
- https://www.explorationpub.com/Journals/eff/Article/101070 – Detailed a meta-analysis protocol focusing on *L. barbarum* with aims to assess its effects on plasma lipid concentrations, adhering to PRISMA guidelines.
- https://www.mdpi.com/2075-1729/14/3/420 – A study showing antioxidative and anti-inflammatory effects of *Lycium barbarum* over an 8-week period, illustrating its potential health benefits.
- https://www.mdpi.com/2673-9976/40/1/1 – Research indicating the overall health-promoting properties of *L. barbarum*, discussing its role in traditional medicine and summarizing trial findings.
- https://www.researchgate.net/publication/230684097_A_Meta-Analysis_of_Clinical_Improvements_of_General_Well-Being_by_a_Standardized_Lycium_barbarum – A meta-analysis highlighting clinical improvements in general well-being attributed to a standardized extract of *Lycium barbarum*, reinforcing its efficacy.