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Macapure

Also known as: Maca, Peruvian Maca, *Lepidium meyenii*

Overview

Maca, scientifically known as *Lepidium meyenii*, is a cruciferous vegetable native to the Andean region of Peru. Traditionally, it has been used for its nutritional and medicinal properties. Primarily, maca is recognized for its potential to enhance sexual function, improve semen quality, and alleviate menopausal symptoms. This adaptogenic herb contains a variety of bioactive compounds, including macamides and glucosinolates, which contribute to its health benefits. Research on maca is evolving, focusing on sexual health, physical performance, and its antioxidant effects. While multiple studies have been conducted, the overall quality of evidence is mixed, with many studies exhibiting methodological limitations, necessitating further research to confirm efficacy and safety.

Benefits

Maca is mostly known for its role in improving erectile function among men with mild erectile dysfunction, demonstrated by a mean difference of 1.13 in a meta-analysis of two randomized controlled trials (RCTs). Furthermore, it appears to enhance physical performance, notably in endurance activities such as forced swimming and rota-rod tests, with significant effect sizes. Secondary benefits may extend to cognitive function, mood stabilization, and supporting bone health, though these claims require further exploration as the evidence is less robust. Ideal populations may include athletes or individuals experiencing sexual health issues, with many reporting noticeable improvements within weeks to months of initiating supplementation.

How it works

The mechanisms of maca's action appear to involve modulation of the NO-cGMP signaling pathway, enhancing erectile function. Additionally, maca may exert antioxidant and anti-inflammatory effects that contribute to various health benefits, potentially influencing hormone regulation and oxidative stress levels within the body. Although specific molecular targets remain unclear, the interactions with reproductive, nervous, and muscular systems suggest a comprehensive role in health enhancement.

Side effects

Maca is generally deemed safe for consumption but may cause mild gastrointestinal upset in some individuals. Rarely, allergic reactions may occur, and caution is warranted in individuals taking blood thinners or hormone therapies due to potential interactions. Contraindications include pregnancy and breastfeeding, given the limited safety data in these populations. Those with thyroid issues should use maca cautiously, as there is a concern it might affect thyroid function. Overall, the side effect profile is mild, and serious adverse effects have not been reported in the literature.

Dosage

The recommended dosage for maca supplementation generally ranges from 1.2 to 3.0 grams per day, with a minimum effective dose starting at 1.2 grams. Doses above 3 grams have not been extensively studied. For best results, consistent daily intake is advised, and it is suggested to take maca with meals to minimize potential gastrointestinal discomfort. Using gelatinized maca root powder may enhance absorption due to its processing method, although the exact bioavailability remains under investigation.

FAQs

How should I take maca?

Maca can be taken with meals to help reduce gastrointestinal discomfort and is best consumed daily for optimal effects.

Is maca safe for everyone?

Maca is generally safe, but caution is advised for pregnant or breastfeeding women and those with thyroid issues.

When can I expect to see results?

Improvements in sexual function or physical performance may be noticed within a few weeks of consistent supplementation.

Can maca treat erectile dysfunction?

Maca may improve symptoms of mild erectile dysfunction, but it is not a proven treatment for severe cases.

What are the common side effects of maca?

Common side effects include gastrointestinal upset, while allergic reactions and potential drug interactions are also possible but rare.

Research Sources

  • https://www.mdpi.com/2076-3921/13/9/1046 – This systematic review assesses the effects of maca on various conditions and emphasizes its potential benefits, particularly for sexual dysfunction and physical performance. It notes that while maca shows promise, the overall quality of studies is moderate due to high reporting bias and other methodological concerns.
  • https://oss.jomh.org/files/article/20230130-20/pdf/JOMH15305.pdf – A systematic review and meta-analysis examining the efficacy of maca for erectile dysfunction indicated that maca may improve erectile function, referencing small sample sizes in RCTs as a limitation and highlighting the low quality of this evidence.
  • https://pubmed.ncbi.nlm.nih.gov/39796542/ – This review discusses maca's effects on physical performance, concluding that while there are significant improvements observed in endurance tests, variability in study methodologies warrants caution in interpreting results.
  • https://www.mdpi.com/2072-6643/17/1/107 – Investigating the health benefits of maca, this review identified various positive effects on endurance and sexual health. However, it found substantial variability in study populations and design, affecting the robustness of conclusions drawn.
  • https://doaj.org/article/93bf7e71fde642b9b1281542fd0244d9 – A large systematic review consolidating findings from multiple studies about maca exhibits its potential in enhancing athletic performance and sexual function, but it also stresses the need for further high-quality research due to prevalent methodological flaws.

Supplements Containing Macapure

HPA Adapt by Integrative Therapeutics
78

HPA Adapt

Integrative Therapeutics

Score: 78/100
Hot Plants For Him by Enzymatic Therapy
70

Hot Plants For Him

Enzymatic Therapy

Score: 70/100
ITI Man by Integrative Therapeutics
83

ITI Man

Integrative Therapeutics

Score: 83/100