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Mangifera Indica Bark Extract

Also known as: Mangifera indica bark extract, Mango tree bark extract, Mangifera indica extract

Overview

Mangifera indica bark extract is derived from the bark of the mango tree, native to South Asia and widely cultivated in tropical regions. This botanical extract is rich in bioactive compounds, most notably mangiferin, a glucosyl xanthone known for its potential antioxidant, anti-inflammatory, and immunomodulatory properties. Traditionally used in Ayurvedic medicine, recent research has focused on its potential to enhance muscle strength and endurance, particularly when combined with resistance training. It is available in various forms, including water-dispersible powders, and is often used in dietary supplements aimed at improving physical performance. While research is still emerging, the extract shows promise as an ergogenic aid, particularly for young males engaged in resistance training. The quality of available evidence is moderate, with several randomized controlled trials supporting its benefits, though more extensive systematic reviews are needed to confirm these findings.

Benefits

The primary benefit of Mangifera indica bark extract, particularly when combined with Sphaeranthus indicus flower head extract, is improved muscle strength and endurance in young males undergoing resistance training. Studies have reported significant improvements in these areas after several weeks of supplementation. Secondary benefits may include antioxidant, anti-inflammatory, and immunomodulatory effects, although these are less extensively studied in the context of muscle performance. The observed benefits are primarily documented in young male populations, and effect sizes can vary across studies. Research suggests that these improvements are typically observed over several weeks of consistent supplementation and training, indicating a time-dependent effect.

How it works

Mangifera indica bark extract is believed to enhance muscle protein synthesis by activating the mTOR pathway and upregulating muscle-specific transcription factors such as myogenin and myoD. This mechanism promotes muscle growth and repair, contributing to increased strength and endurance. Additionally, the extract's antioxidant properties may reduce oxidative stress associated with intense exercise, further supporting muscle function. Mangiferin, a key component, may also interact with various pathways related to inflammation, potentially aiding in muscle recovery. However, specific details on the absorption and bioavailability of the extract remain limited, requiring further investigation.

Side effects

Mangifera indica bark extract is generally considered safe, with few reported adverse effects in clinical trials. Common side effects are rare and typically minor, including occasional body aches and mild gastrointestinal discomfort. No uncommon or rare side effects have been consistently documented in available studies. While specific drug interactions are not well-defined, there is a potential for interactions with medications affecting blood sugar or inflammation. As a precaution, pregnant or breastfeeding women should consult healthcare providers before using this supplement due to limited safety data in these populations. Overall, the safety profile appears favorable, but continued monitoring and research are necessary to fully characterize potential risks.

Dosage

The minimum effective dose of Mangifera indica bark extract, when used in combination with Sphaeranthus indicus, is typically around 650 mg per day for the combined extract. Optimal dosage ranges studied in clinical trials vary from 425 mg to 850 mg per day of the combined extract. The maximum safe dose has not been definitively established, so it is important to adhere to recommended dosages. Daily supplementation is common, and water-dispersible forms are available for improved absorption. There are no documented required cofactors for its use. It is advisable to consult with a healthcare provider to determine the most appropriate dosage based on individual health status and fitness goals.

FAQs

How should I use Mangifera indica bark extract for best results?

For optimal benefits, use it in conjunction with a balanced diet and regular exercise, particularly resistance training. Consistency is key, and results are typically observed over several weeks.

Is Mangifera indica bark extract safe to use?

It is generally considered safe, but consult a healthcare provider if you have underlying health conditions or are taking medications that affect blood sugar or inflammation.

When is the best time to take Mangifera indica bark extract?

It is typically taken once daily. The timing is not critical, but consistency is important. Choose a time that is convenient for you to ensure regular intake.

What results can I expect from taking Mangifera indica bark extract?

You can expect improved muscle strength and endurance over several weeks when combined with resistance training. It is not a standalone solution for muscle gain and requires consistent exercise.

Are there any misconceptions about Mangifera indica bark extract?

Yes, it's not a magic bullet. It requires consistent exercise and a balanced diet to be effective. It enhances, but does not replace, the need for a healthy lifestyle.

Research Sources

https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2024.1393917/full – This study examined the effects of different doses (425 mg and 850 mg) of a Sphaeranthus indicus and Mangifera indica extract blend on muscle strength and endurance in young men undergoing resistance training. The results indicated that both doses led to significant improvements compared to a placebo group, suggesting a dose-dependent effect on muscle performance.
https://archive.is/M2Zwe – This archived article likely discusses the general properties and traditional uses of Mangifera indica, including its antioxidant and anti-inflammatory effects. It provides background information on the plant's historical applications and potential health benefits beyond muscle performance, such as its role in Ayurvedic medicine.
https://foodandnutritionresearch.net/index.php/fnr/article/download/8972/15277/ – This research article likely explores the nutritional aspects of Mangifera indica and its potential health benefits. It may delve into the specific compounds present in the plant, such as mangiferin, and their mechanisms of action related to antioxidant and anti-inflammatory effects.
https://academic.oup.com/nutritionreviews/advance-article/doi/10.1093/nutrit/nuae214/7998593 – This article in Nutrition Reviews likely provides a comprehensive review of the existing literature on Mangifera indica and its various health benefits. It may offer a critical analysis of the available evidence, including both preclinical and clinical studies, to assess the overall efficacy and safety of the extract.
https://journals.sagepub.com/doi/abs/10.1177/11786388231204200 – This study evaluated the effects of a proprietary blend of Sphaeranthus indicus and Mangifera indica extracts on muscle strength and endurance. Forty male participants received either 650 mg/day of the blend or a placebo for 56 days, with significant improvements observed in the supplemented group, suggesting a synergistic effect of the two extracts.