Melia Azadirachta Flower Extract
Also known as: Azadirachta indica Flower Extract, Neem Flower Extract, Melia azedarach Flower Extract, Chinaberry Flower Extract
Overview
Azadirachta indica, commonly known as Neem, is a plant widely used in traditional medicine. While 'Melia Azadirachta Flower Extract' is likely a misnomer, often confused with either Azadirachta indica (Neem) or Melia azedarach (Chinaberry), both belonging to the Meliaceae family. These plants, particularly their flower extracts, are explored for their medicinal properties, including antimicrobial, antiviral, and potential anticancer effects. The extracts are rich in phenolic and flavonoid compounds, contributing to their bioactivity. Research on Azadirachta indica is more extensive compared to Melia azedarach, with the latter primarily based on in vitro studies. Due to the limited specific research on Melia azadirachta flower extract, information is often extrapolated from studies on related plant parts or species.
Benefits
Azadirachta indica flower extract demonstrates antimicrobial and antiviral activities, with some studies suggesting anti-SARS-CoV-2 activity. Research indicates that the antimicrobial action involves disruption of bacterial cell walls and membranes. While potential anticancer properties have been noted, further research is required to substantiate these claims. The IC50 for anti-SARS-CoV-2 activity was reported as 6.922 μg/mL for Melia azedarach. However, specific population-based benefits and the time course of these benefits are not well-documented for flower extracts. More research is needed to fully understand and validate these benefits.
How it works
The antimicrobial activity of Azadirachta indica flower extract is thought to primarily involve the disruption of bacterial cell walls and membranes. The extract's rich composition of phenolic and flavonoid compounds contributes to its bioactivity. However, the specific molecular targets and systemic interactions of Melia azedarach flower extract are not well-defined. Further research is needed to elucidate the precise mechanisms of action, including absorption, bioavailability, and interaction with various body systems.
Side effects
While Azadirachta indica is generally considered safe when used appropriately, specific safety data for Melia azedarach flower extract is limited. Common, uncommon, and rare side effects are not well-documented for the flower extract. Potential drug interactions are also not well-studied. Caution is advised during pregnancy and lactation due to the lack of comprehensive safety data. Further research is necessary to establish a complete safety profile and identify any potential adverse effects or contraindications.
Dosage
Currently, there is no established minimum effective dose, optimal dosage range, or maximum safe dose for Melia azedarach flower extract. Timing considerations, form-specific recommendations, absorption factors, and required cofactors are also not yet determined. Due to the limited research, it is crucial to exercise caution and consult with a healthcare professional before using this extract. Further studies are needed to provide evidence-based dosing guidelines.
FAQs
What are the practical usage concerns for Melia azedarach flower extract?
Due to the lack of specific data on flower extract usage, practical applications are not well-defined. Caution is advised, and further research is needed to establish safe and effective usage guidelines.
Are there any safety clarifications I should be aware of?
Given the limited safety data, caution is advised when considering the use of Melia azedarach flower extract. Consult with a healthcare professional before use, especially if pregnant, breastfeeding, or taking other medications.
What results can I expect from using this extract?
Based on related plant parts, antimicrobial benefits may be expected. However, specific results from the flower extract are not well-documented, and further research is needed to confirm its efficacy.
Is Melia azedarach flower extract the same as other plant parts?
No, it is not the same. While derived from the same plant family, the flower extract may have different properties and effects compared to other plant parts. Research on the flower extract is limited.
Research Sources
- https://pmc.ncbi.nlm.nih.gov/articles/PMC9994683/ – This study investigated the antimicrobial activity of Azadirachta indica and Melia azedarach leaves. The results showed antibacterial activity against various strains, with MICs ranging from 25 to 100 mg/mL, indicating potential for use in antimicrobial applications.
- https://pmc.ncbi.nlm.nih.gov/articles/PMC6997857/ – This research provides a phytochemical analysis of both plants, revealing the presence of steroids, alkaloids, phenols, flavonoids, saponins, tannins, and anthraquinones. These compounds contribute to the plants' bioactivity, supporting their use in traditional medicine.
- https://researcherslinks.com/current-issues/Fascioliasis-Phytotherapy-using-Tropical-Plant-Extracts-A-Systematic-Review-with-Meta-Analysis/36/8/5871/html – This systematic review with meta-analysis explores the use of tropical plant extracts for phytotherapy in treating Fascioliasis. It highlights the potential of plant-based treatments, though specific details on Melia azedarach or Azadirachta indica are not the primary focus.
- https://acopen.umsida.ac.id/index.php/acopen/article/view/10424 – This comparative study assesses the insecticidal activity of Azadirachta indica and Melia azedarach. The findings indicate that Azadirachta indica was more effective than Melia azedarach in killing Musca domestica at higher concentrations, suggesting potential applications in pest control.
- https://atm.amegroups.org/article/view/97030/html – This article discusses the broader applications of traditional medicine and herbal remedies. While it may not specifically focus on Melia azedarach or Azadirachta indica flower extracts, it provides context on the use of plants in medicine.
