ProveIt Supplements

Independent, evidence-based supplement analysis.

✓ Not Sponsored

✓ No Paid Reviews

✓ Science-Based

Company

  • About Us
  • Our Methodology
  • Contact
  • Blog
  • Authors

Legal

  • Privacy Policy
  • Terms of Service
  • Medical Disclaimer
  • Affiliate Disclosure

Resources

  • All Categories
  • Ingredient Database
  • Browse Supplements
  • FAQ

© 2025 ProveIt Supplements. All rights reserved.

Medical Disclaimer: The information provided is for educational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen.

Prove It
Browse SupplementsBlogAuthorsAboutMethodologyFAQ
Get Your Personalized Supplement StackSupplement Stack Quiz
Menu
HomeBrowse SupplementsBlogAuthorsAboutMethodologyFAQ
Back

Microbiomex

Also known as: MicrobiomeX, Citrus flavonoid complex, Hesperidin, Naringin, Citrus sinensis extraction, Citrus paradisi extraction

Overview

MicrobiomeX is a sophisticated citrus flavonoid complex derived mainly from hesperidin and naringin, sourced from Citrus sinensis (sweet orange) and Citrus paradisi (grapefruit). This supplement is formulated to enhance gut and immune health by effectively modulating the gut microbiome. It supports significant improvements in gut barrier function, helps alleviate gut inflammation, and encourages the production of beneficial short-chain fatty acids (SCFAs), notably butyrate, which plays a critical role in gut health. Evidence from various clinical and pre-clinical studies demonstrates promising effects, especially in individuals suffering from metabolic syndrome, underlining its potential as a functional ingredient for promoting digestive wellness and overall health.

Benefits

MicrobiomeX has been found to significantly enhance the production of butyrate, a key SCFA, while also reducing markers of gut inflammation such as calprotectin. Notably, research indicates a significant shift towards increased butyrate levels (p=0.022) following 12 weeks of supplementation, making it particularly beneficial for individuals with metabolic syndrome characteristics. Secondary benefits also include improved overall gut health, as evidenced by lower inflammatory markers and bolstered gut barrier function. The strength of this evidence, drawn from moderate quality studies, suggests a substantive role for MicrobiomeX in enhancing gut health and potentially aiding metabolic health outcomes.

How it works

MicrobiomeX functions by modulating the gut microbiome’s composition, promoting a favorable environment for beneficial SCFA production and mitigating gut inflammation. It enhances the gut barrier's integrity, which is pivotal for regulating immune responses throughout the body. Its interactions with the microbiota ensure a balanced production of SCFAs, which are essential for maintaining gut health and general homeostasis, leading to improved metabolic conditions in the body.

Side effects

MicrobiomeX is generally considered safe, with no significant adverse effects reported in scientific studies. No common side effects (>5%) have been documented, nor are there any uncommon (1-5%) or rare (<1%) side effects identified. Importantly, no significant drug interactions have been reported, making it suitable for various populations without specific contraindications, including pregnant women, children, and the elderly. Nonetheless, individuals are encouraged to consult healthcare providers to address any personal health issues or concerns related to MicrobiomeX usage.

Dosage

The recommended minimum effective dose of MicrobiomeX is 500 mg per day, which is recognized as the optimal dosage for achieving the desired benefits. While the maximum safe dose has not been explicitly established, the 500 mg dose is generally well-tolerated when taken daily. There are no specific timing recommendations for consumption, allowing users flexibility in administration. MicrobiomeX is available in various forms — capsules, tablets, and beverages — with bioavailability potentially varying based on individual gut microbiota differences. No additional cofactors are required to maximize its effectiveness.

FAQs

How long does it take to see benefits?

Benefits are generally observed after 12 weeks of consistent supplementation with MicrobiomeX.

Is MicrobiomeX safe for everyone?

MicrobiomeX is considered generally safe, but it’s advisable to consult a healthcare provider if there are any uncertainties about its usage.

What is the recommended timing for taking MicrobiomeX?

There are no specific timing recommendations for taking MicrobiomeX; it can be taken at any time of day.

What results can I expect?

Users can expect improvements in gut health and a reduction in inflammation with regular use.

Is MicrobiomeX a substitute for probiotics?

No, MicrobiomeX is not a replacement for probiotics but can complement them in supporting gut health.

Supplements Containing Microbiomex

PhytoPre by Ortho Molecular Products
75

PhytoPre

Ortho Molecular Products

Score: 75/100
Prebiotic V by HoltraCeuticals
83

Prebiotic V

HoltraCeuticals

Score: 83/100
Gut Balance by Body Kitchen
73

Gut Balance

Body Kitchen

Score: 73/100
Flavofight 500 mg by SuperSmart
80

Flavofight 500 mg

SuperSmart

Score: 80/100
Flavofight 500 mg by SuperSmart
75

Flavofight 500 mg

SuperSmart

Score: 75/100
Synbiotic by Salaam Nutritionals
65

Synbiotic

Salaam Nutritionals

Score: 65/100
Gut 4-tify by Just Thrive
83

Gut 4-tify

Just Thrive

Score: 83/100
Bio.Me Essential by Invivo
88

Bio.Me Essential

Invivo

Score: 88/100
Bio.Revive Kinetic by Invivo
83

Bio.Revive Kinetic

Invivo

Score: 83/100
SERENE SKIN by Microbiome Labs
73

SERENE SKIN

Microbiome Labs

Score: 73/100
TARGETED PREBIOTIC PreticX® + MicrobiomeX® + ApplePhenon® by SILVER FERN BRAND™
70

TARGETED PREBIOTIC PreticX® + MicrobiomeX® + ApplePhenon®

SILVER FERN BRAND™

Score: 70/100
MegaMucosa Stick Packs by Microbiome Labs
68

MegaMucosa Stick Packs

Microbiome Labs

Score: 68/100