Citrus Bioflavonoids
Also known as: hesperidin, naringin, narirutin, didymin, eriocitrin, diosmin, diosmetin, naringenin, neohesperidin, nobiletin, tangeretin, rutin, Citrus bioflavonoids, vitamin P, Citrus Bioflavonoids
Overview
Citrus bioflavonoids are a group of phytochemicals predominantly found in the rind and pulp of citrus fruits such as oranges, lemons, limes, grapefruits, and tangerines. These compounds are notable for their antioxidant and anti-inflammatory properties, which can support immune function, vascular health, and metabolic health. They are often used alongside vitamin C to enhance its absorption and effectiveness. Research into citrus bioflavonoids is still developing, with a confidence rating of 7/10; their antioxidant and anti-inflammatory effects are well-supported, but more clinical studies are needed to confirm other potential benefits.
Benefits
Citrus bioflavonoids offer several evidence-based health benefits. One of the primary benefits is their high antioxidant activity, which has an evidence rating of 8/10, indicating their effectiveness in combating oxidative stress crucial for heart and immune health. Additionally, they demonstrate high anti-inflammatory properties, also rated at 8/10, by modulating inflammation in various tissues. Other benefits include moderate evidence for immune system support (6/10), metabolic health (6/10), and vascular health (6/10). Research indicates significant reductions in oxidative stress, with hesperidin linked to lower oxidative stress levels in animal studies. Benefits may be observed both short-term and long-term.
How it works
Citrus bioflavonoids function primarily by neutralizing free radicals, thus reducing oxidative stress and inflammation. They enhance the stability and absorption of vitamin C, allowing for synergistic effects within the body. Their interaction with various enzymes and receptors involved in inflammatory processes substantiates their role in supporting immune function and vascular health. These compounds initiate biological responses that promote cellular health and mitigate the symptoms associated with oxidative damage.
Side effects
Citrus bioflavonoids are generally considered safe, but users may experience common side effects, including headache, dizziness, skin itchiness, and leg swelling or pain, occurring in more than 5% of users. Uncommon side effects may include blurred vision, alterations in heart rate, and ear pounding, occurring between 1% to 5%. Rare side effects, occurring in fewer than 1% of users, can include allergic reactions such as hives and difficulty breathing. Caution is advised for individuals taking anticoagulant medications like warfarin, as interactions may occur. Pregnant or breastfeeding individuals, as well as those with chronic medical conditions, should consult healthcare providers prior to use.
Dosage
For optimal benefits, a typical dosage range for citrus bioflavonoids is between 250 mg to 1.4 g per day. Some products combine them with 100-500 mg of vitamin C. It's generally recommended to take these supplements with meals to improve absorption. While specific maximum dosages are not well established, up to 1.4 g per day has been utilized safely in various studies. Consideration should be given to individual health conditions and specific formulations available.
FAQs
Are citrus bioflavonoids safe?
Generally considered safe, but individuals with certain medical conditions or on specific medications should consult their healthcare provider.
When is the best time to take citrus bioflavonoids?
These supplements are best taken with meals to enhance their absorption.
What benefits can I expect?
Antioxidant and anti-inflammatory effects, along with improved immune and metabolic health.
Can citrus bioflavonoids replace medical treatment?
No, they should not be considered a substitute for medical treatment and should be used under healthcare provider guidance if for therapeutic purposes.
Research Sources
- https://drmonicascheel.com/product/citrus-bioflavonoids/ – Dr. Monica Scheel discusses the role of citrus bioflavonoids in supplement formulations and highlights their antioxidant properties, indicating practical usage for health benefits.
- https://www.mindbodygreen.com/articles/citrus-bioflavonoids – MindBodyGreen provides an overview of citrus bioflavonoids, summarizing their health benefits, safety profile, and how they interact with vitamin C for enhanced absorption.
- https://www.drugs.com/mtm/bioflavonoids.html – Drugs.com covers the usage, benefits, and potential side effects of bioflavonoids, including citrus bioflavonoids, emphasizing caution for specific populations.
