ProveIt Supplements

Independent, evidence-based supplement analysis.

✓ Not Sponsored

✓ No Paid Reviews

✓ Science-Based

Company

  • About Us
  • Our Methodology
  • Contact
  • Blog
  • Authors

Legal

  • Privacy Policy
  • Terms of Service
  • Medical Disclaimer
  • Affiliate Disclosure

Resources

  • All Categories
  • Ingredient Database
  • Browse Supplements
  • FAQ

© 2025 ProveIt Supplements. All rights reserved.

Medical Disclaimer: The information provided is for educational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen.

Prove It
Browse SupplementsBlogAuthorsAboutMethodologyFAQ
Get Your Personalized Supplement StackSupplement Stack Quiz
Menu
HomeBrowse SupplementsBlogAuthorsAboutMethodologyFAQ
Back

Nem Eggshell Membrane

Also known as: NEM Eggshell Membrane, Eggshell Membrane Extract, NEM®, NEM® Brand Eggshell Membrane

Overview

NEM® Brand Eggshell Membrane is a dietary supplement sourced from the membrane of eggshells. It is rich in essential glycosaminoglycans such as chondroitin sulfate, hyaluronic acid, and keratan sulfate, alongside proteins including collagen Type I. Commonly used to support joint health, alleviate joint pain and stiffness, and aid recovery from exercise, NEM® also shows promise in treating osteoarthritis. Studies reveal substantial content of key components including glucosamine (1%), chondroitin sulfate (1%), and hyaluronic acid (2%). Numerous clinical trials, including randomized controlled trials, confirm its efficacy, albeit a lack of comprehensive systematic reviews exists.

Benefits

NEM® provides multiple evidence-based benefits, notably a significant reduction in joint pain and stiffness within 10 days of use, with a reported 78% reduction in analgesic consumption during this period. It protects cartilage by lowering CTX-II levels, a biomarker indicative of cartilage degradation. Particularly beneficial for individuals with osteoarthritis, NEM® alleviates knee and hip pain and stiffness. Athletes and those engaged in moderate intensity aerobic exercises also report remarkable joint relief, supported by statistically significant study findings demonstrating sustained benefits over time.

How it works

NEM® works by supplying crucial glycosaminoglycans and proteins that are vital for joint health while reducing inflammation. Its bioactive components inhibit pro-inflammatory cytokines, such as IL-1β and TNF-α, which are key players in joint inflammation. By targeting joint tissue, NEM® mitigates inflammatory markers and supports the musculoskeletal system through the enhancement of connective tissues, aided by proprietary processing that improves bioavailability.

Side effects

NEM® exhibits a favorable safety profile and is generally well-tolerated. Clinical studies report no serious adverse effects, with no common (over 5%) or rare (<1%) side effects documented. There is no significant evidence of drug interactions or specific contraindications. However, caution is warranted for special populations, including pregnant women, children, and individuals with severe chronic health issues, as evidence in these groups remains limited.

Dosage

The recommended dosage of NEM® is 500 mg once daily, demonstrated to be effective in various clinical studies. This dosage is recognized as the minimum effective dose, with no established maximum safe dosage indicated. Consistent use of 500 mg per day has been reported without adverse reactions. The timing of administration is flexible, yet it is advisable to take it once daily, typically in capsule form. Proprietary processing also enhances the bioavailability of its components, though specific absorption factors require further exploration.

FAQs

How quickly can I expect to see results?

Benefits can be observed as early as 10 days of use.

Is NEM® safe?

It has been reported to be well-tolerated with no serious adverse events noted.

Can I use NEM® if I have other health conditions?

There is limited information on its use in special populations, so caution is advised.

What are the expected results?

Significant reduction in joint pain and stiffness, as well as decreased need for analgesics.

Is NEM® a quick fix for joint pain?

NEM® provides sustained benefits over time, rather than immediate relief.

Supplements Containing Nem Eggshell Membrane

Eggshell Membrane 500 mg by NOW
82

Eggshell Membrane 500 mg

NOW

Score: 82/100
Eggshell Membrane 500 mg by Healthy Origins
83

Eggshell Membrane 500 mg

Healthy Origins

Score: 83/100
Eggshell Membrane 500 mg by Healthy Origins
90

Eggshell Membrane 500 mg

Healthy Origins

Score: 90/100
Eggshell Membrane 500 mg by Healthy Origins
82

Eggshell Membrane 500 mg

Healthy Origins

Score: 82/100
Eggshell Membrane 500 mg by NOW
83

Eggshell Membrane 500 mg

NOW

Score: 83/100
Joint Advantage Gold 5X by Dr. David Williams
73

Joint Advantage Gold 5X

Dr. David Williams

Score: 73/100
Joint Advantage Gold Original by Dr. David Williams
83

Joint Advantage Gold Original

Dr. David Williams

Score: 83/100
Turmeric Curcumin Q+ by Zenwise Health
78

Turmeric Curcumin Q+

Zenwise Health

Score: 78/100

Recommended Articles

Collagen Supplements & Skin Aging: A Meta-Analysis Review

Collagen Supplements & Skin Aging: A Meta-Analysis Review

Meta-analyses confirm collagen supplementation significantly improves skin elasticity, hydration, and wrinkling.