Nutriderm
Also known as: Nutriderm, Nutritional Supplement, Oral Nutritional Supplement (ONS)
Overview
Nutriderm is a proprietary nutritional supplement, likely formulated as an Oral Nutritional Supplement (ONS), designed to support recovery, improve metabolic health, and enhance overall nutritional status. While 'Nutriderm' itself is a brand name and not a single chemical entity, its intended use aligns with the broader category of ONS products used in clinical nutrition. These supplements typically contain a combination of macronutrients (proteins, carbohydrates, fats) and micronutrients (vitamins, minerals) aimed at addressing nutritional deficiencies, supporting physiological functions, and aiding recovery from various conditions. Common applications include improving post-exercise fatigue recovery, supporting glycemic control in individuals with metabolic disorders, and reducing hospital readmissions in malnourished or at-risk populations, particularly older adults. The exact composition of Nutriderm is not specified in the provided research, but it is expected to provide essential nutrients, antioxidants, and cofactors to support cellular energy metabolism and reduce oxidative stress.
Benefits
Nutritional supplements, including those in the ONS category like Nutriderm, offer several evidence-based benefits. They significantly improve post-exercise fatigue recovery, with a statistically significant effect size of 0.269 (p=0.022, 95% CI [0.039, 0.498]), making them beneficial for individuals engaged in physical activity. For patients with type 2 diabetes, pharmaconutrients often found in such supplements, like chromium, coenzyme Q10, and vitamins C and E, have been shown to significantly improve glycemic control by reducing HbA1c, fasting blood glucose, and insulin resistance markers. Furthermore, oral nutritional supplements significantly reduce hospital readmissions, especially in older adults, with observed odds ratios around 0.59 (95% CI 0.43-0.80, p=0.001). This highlights their crucial role in improving outcomes for malnourished or at-risk populations. Secondary benefits include improved metabolic parameters and reduced healthcare utilization. The benefits are observed over weeks to months, with moderate to significant effect sizes demonstrating clinical relevance.
How it works
Nutritional supplements like Nutriderm primarily function by providing essential nutrients, antioxidants, and cofactors that support and enhance various metabolic pathways. They contribute to improved cellular energy metabolism by supplying necessary substrates and coenzymes. The antioxidant components, such as vitamins C and E, help reduce oxidative stress, which is crucial for cellular health and recovery. Ingredients like chromium can improve insulin sensitivity, thereby aiding in glycemic regulation. Coenzyme Q10 supports mitochondrial function, which is vital for energy production. Overall, these supplements interact with muscular recovery systems, glycemic regulation pathways, and the immune system, contributing to enhanced nutritional status and reduced risk of complications like hospital readmissions. The absorption and bioavailability are dependent on the specific formulation and nutrient types, typically administered orally.
Side effects
Oral nutritional supplements and pharmaconutrients generally exhibit a good safety profile when used appropriately. The most common side effects, occurring in over 5% of users, are mild gastrointestinal discomfort, which may include bloating, gas, or mild stomach upset. Uncommon side effects, affecting 1-5% of users, can include allergic reactions or intolerance to specific components within the supplement formulation. Rare side effects, occurring in less than 1% of users, are not significantly reported as serious adverse events in high-quality randomized controlled trials. Potential drug interactions exist, particularly with antidiabetic medications, where ingredients like chromium could enhance their effects, necessitating careful monitoring of blood glucose levels. Antioxidants may also interact with certain medications. Contraindications include known allergies to any of the supplement's components. Caution is advised for patients with specific metabolic disorders, and individuals in special populations, such as older adults and those with chronic diseases, should use these supplements under medical supervision to ensure safety and appropriateness.
Dosage
The optimal dosage for nutritional supplements like Nutriderm is highly dependent on its specific nutrient composition and the individual's nutritional needs and health goals. For instance, in studies focusing on glycemic effects, chromium dosages typically ranged from 200-1000 mcg per day. For general oral nutritional supplements, dosing is often tailored to meet specific caloric and protein requirements, particularly in malnourished patients. There is no identified maximum safe dose specifically for Nutriderm, but individual nutrients within such formulations have established upper limits to prevent toxicity. Timing considerations can influence efficacy; for example, some evidence suggests post-exercise administration for improved recovery from fatigue. These supplements are typically administered orally. Absorption can be influenced by factors such as co-administration with meals, which may enhance the absorption of fat-soluble vitamins, while some minerals might compete for absorption. Adequate hydration and a balanced diet are important cofactors that can enhance the overall efficacy of the supplement.
FAQs
Is Nutriderm safe for long-term use?
Based on general safety data for Oral Nutritional Supplements (ONS), Nutriderm is likely safe for long-term use when taken as directed and under appropriate medical supervision, especially for individuals with ongoing nutritional needs.
Can Nutriderm improve blood sugar control?
If Nutriderm contains pharmaconutrients like chromium or antioxidants (e.g., vitamins C and E), it may support glycemic control as an adjunct therapy, as these ingredients have shown benefits in managing blood sugar levels.
When is the best time to take Nutriderm?
The best time to take Nutriderm can depend on its intended use. For recovery benefits, post-exercise administration may be optimal. Otherwise, it should be taken as prescribed by healthcare providers to maximize its benefits.
How soon can benefits be expected?
Improvements in fatigue and glycemic markers may be observed within weeks of consistent use. More significant outcomes, such as reductions in hospital readmissions, have been noted over several months of supplementation.
Is Nutriderm suitable for elderly patients?
Yes, Nutriderm is particularly suitable for elderly patients, especially those at risk of malnutrition, as oral nutritional supplements have been shown to reduce malnutrition-related complications and hospital readmissions in this population.
Research Sources
- https://www.frontiersin.org/journals/nutrition/articles/10.3389/fnut.2025.1567438/full – This systematic review and meta-analysis by Cheng et al. (2025) investigated the timing of nutritional supplements on post-exercise fatigue recovery. The study included multiple RCTs and found a significant positive effect (effect size 0.269, p=0.022), suggesting that nutritional supplementation can aid in recovery. Limitations included heterogeneity across included studies and variable supplement types.
- https://pubmed.ncbi.nlm.nih.gov/35304727/ – Kim et al. (2022) conducted a systematic review and meta-analysis assessing pharmaconutrient add-ons in type 2 diabetes, analyzing 119 RCTs with over 9000 participants. They found that chromium, coenzyme Q10, and vitamins C and E significantly improved glycemic control markers such as HbA1c, fasting blood glucose, and HOMA-IR. The study's strengths include its large sample size and rigorous methodology, though variability in study duration and baseline HbA1c were noted limitations.
- https://pubmed.ncbi.nlm.nih.gov/23891685/ – Stratton et al. (2013) performed a systematic review and meta-analysis examining the impact of oral nutritional supplements on hospital readmissions, based on 9 RCTs involving 1190 patients. The findings indicated a significant reduction in readmissions (OR 0.59, p=0.001), particularly in older adults. The study acknowledged limitations such as moderate sample sizes and some heterogeneity in patient populations.
