Nutrilite Parsley Concentrate
Also known as: Parsley, Garden Parsley, Rock Parsley, *Apium graveolens*
Overview
Parsley (*Apium graveolens*) is a popular herb from the Apiaceae family, widely known for its culinary and medicinal uses. Rich in bioactive compounds, including flavonoids and phenolic compounds, it is utilized for various health benefits, such as diuretic, antidiabetic, antithrombotic, and hypolipidemic effects. Notable compounds found in parsley include myristicin, apiol, and apigenin. Parsley is typically consumed fresh, dried, or in concentrated extracts. While studies on its health benefits are promising, further large-scale clinical trials are necessary to verify its clinical significance and optimize usage guidelines.
Benefits
Research suggests several evidence-based benefits of parsley: it exhibits diuretic effects as shown by increased urine output in animal studies by inhibiting sodium reabsorption. It also demonstrates antidiabetic properties, reducing blood glucose levels and improving insulin secretion. Significant reductions in platelet aggregation illustrate its antithrombotic potential. Secondary benefits include hypolipidemic effects, with evidence of reduced cholesterol and triglycerides in hypercholesterolemic models, and protection against oxidative stress, particularly in renal health. Specific populations, such as diabetic patients and those seeking renal health support, may benefit the most.
How it works
Parsley’s mechanisms primarily involve the inhibition of the Na+/K+ -ATPase enzyme, enhancing diuretic effects, and protective actions on pancreatic β-cells through antioxidant properties. Its flavonoids, like apigenin, play a role in increasing insulin secretion and enhancing glucose metabolism, while also preventing platelet aggregation, thus contributing to its antithrombotic and cardiovascular benefits.
Side effects
Parsley is generally safe when consumed in moderation, but potential side effects include gastrointestinal upset due to its diuretic effects. Allergic reactions may occur in sensitive individuals. Rarely, severe allergic reactions and interactions with medications, particularly diuretics and anticoagulants, could happen. Special populations, such as pregnant or breastfeeding women and those with kidney disease, should consult healthcare providers before use. A lack of long-term safety data emphasizes the need for caution.
Dosage
Currently, specific dosages for parsley supplements are not firmly established. The minimum effective dose is yet to be defined, but studies suggest varying dosage ranges depending on the desired effect, with some involving approximately 3.73–4.49 mg of apigenin per MJ of energy intake. Optimal timing for diuretic effects may be in the morning, while individual factors and forms of parsley (fresh, dried, extract) may influence absorption and bioavailability. Maximum safe doses require further investigation.
FAQs
Is parsley safe for long-term use?
Although parsley is generally safe, long-term use should be approached with caution, especially in those on medications.
When is the best time to take parsley supplements?
Taking parsley in the morning may enhance its diuretic effects, while timing for other benefits can vary.
What health improvements can I expect from parsley?
Users may experience better renal health, improved blood glucose control, and potential reductions in cholesterol.
Can parsley replace my current medications?
No, parsley should not substitute medical treatments but may complement them under supervision.
Research Sources
- https://www.frontiersin.org/journals/medicine/articles/10.3389/fmed.2024.1494740/full – This article reviews parsley’s nephroprotective effects and highlights its diuretic properties along with the molecular mechanisms involved, particularly the inhibition of the Na+/K+ -ATPase enzyme.
- https://pubmed.ncbi.nlm.nih.gov/35277031/ – Research demonstrating parsley’s efficacy in reducing blood glucose levels and enhancing insulin secretion, focusing on its antioxidant capabilities to protect pancreatic cells.
- https://www.tandfonline.com/doi/full/10.1080/10942912.2023.2236329 – This study showcases the antithrombotic effects of parsley, indicating its ability to inhibit platelet aggregation and suggesting therapeutic potential in cardiovascular issues.
- https://www.amway.com/en_US/nutrilite – Overview of Nutrilite products, including those containing parsley concentrate, highlighting its health benefits and use in dietary supplements.
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