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Organic American Wormseed

Also known as: Wormseed, American Wormseed, Chenopodium, Teloxys ambrosioides, Epazote, Chenopodium ambrosioides

Overview

Chenopodium ambrosioides, commonly known as American Wormseed, is a plant native to Central and South America. It has a long history of traditional use, primarily as an anthelmintic to treat intestinal parasites. The plant contains ascaridole, a compound believed to be responsible for its anti-parasitic effects. While traditionally used for expelling intestinal worms and as a flavoring in cooking, scientific evidence supporting its efficacy as a supplement is limited. Most available information is based on observational studies and traditional use, with few rigorous clinical trials to confirm its benefits and safety. The plant's leaves and stems are sometimes used as flavorings, but concentrated forms, especially the oil extract, can be toxic and should be avoided.

Benefits

The primary traditional benefit of Chenopodium ambrosioides is its use as an anthelmintic to treat intestinal parasites. However, there is limited high-quality scientific evidence to support this claim. Some anecdotal reports suggest potential benefits for gastrointestinal issues, but these are not well-studied. While it may be beneficial for populations with a high incidence of intestinal parasites, more rigorous research is needed to confirm its efficacy and safety. The effect sizes and clinical significance of Wormseed are not well-documented due to the lack of robust clinical trials. Therefore, any potential benefits should be approached with caution and under the guidance of a healthcare professional.

How it works

The primary mechanism of action of Chenopodium ambrosioides is attributed to ascaridole, a compound found in the plant. Ascaridole is believed to paralyze intestinal worms, facilitating their expulsion from the body. This action primarily affects the gastrointestinal system. However, the specific molecular targets and detailed biological pathways are not well-defined. Limited data is available regarding the absorption and bioavailability of ascaridole and other active compounds in Wormseed. Further research is needed to fully elucidate the mechanisms by which Wormseed may exert its traditional anthelmintic effects.

Side effects

While Chenopodium ambrosioides is generally considered safe when used in small amounts as a food flavoring, concentrated forms, particularly the oil extract, can be toxic. Common side effects may include gastrointestinal upset. Uncommon side effects can include allergic reactions. Rare but severe side effects include significant toxicity, especially with the oil extracts, which can cause neurological and hepatic damage. Drug interactions are not well-studied. It is contraindicated for pregnant women, children, and individuals with pre-existing liver or kidney conditions due to the potential for toxicity. Special caution should be exercised when considering its use in any population, and it should be avoided in children and pregnant women due to the elevated risk of adverse effects.

Dosage

There is no established minimum effective dose, optimal dosage range, or maximum safe dose for Chenopodium ambrosioides as a supplement, due to the lack of rigorous scientific studies. Traditional use involves small amounts of the leaves and stems as a condiment. Concentrated forms, especially the oil extract, should be avoided due to the risk of toxicity. There are no established timing considerations, form-specific recommendations beyond avoiding the oil, or required cofactors. Due to the potential for toxicity, it is crucial to exercise extreme caution and consult with a healthcare professional before considering the use of Wormseed in any form.

FAQs

How should I use American Wormseed?

Use only as a flavoring in small amounts. Avoid concentrated forms like oil extracts due to the risk of toxicity. Consult a healthcare professional before use.

Is American Wormseed safe for children and pregnant women?

No, American Wormseed is not safe for children and pregnant women due to the potential for toxicity. Avoid use in these populations.

What are the expected results from using American Wormseed?

Traditional use suggests relief from intestinal parasites, but scientific evidence is limited. Consult a healthcare professional for effective and safe treatment options.

Can American Wormseed interact with other medications?

Drug interactions are not well-studied. Consult with a healthcare professional to discuss potential interactions with any medications you are taking.

Research Sources

https://www.mdpi.com/2304-8158/10/1/65 – This review discusses the ethnobotanical uses, phytochemistry, and pharmacological activities of Chenopodium ambrosioides. It highlights the plant's traditional use in treating various ailments, including parasitic infections, and identifies its key chemical constituents, such as ascaridole, while emphasizing the need for further research to validate its therapeutic potential and safety.
https://www.utep.edu/herbal-safety/herbal-facts/herbal%20facts%20sheet/wormseed.html – This fact sheet provides safety information about Wormseed, emphasizing the potential toxicity associated with its use, particularly in concentrated forms like the oil extract. It advises caution and highlights the importance of consulting with a healthcare professional before using Wormseed for any medicinal purpose, especially for vulnerable populations like children and pregnant women.
https://www.mdpi.com/2076-3417/13/18/10239 – This study investigates the chemical composition and biological activities of essential oils from Chenopodium ambrosioides. It identifies various bioactive compounds and assesses their potential antimicrobial and antioxidant properties, contributing to a better understanding of the plant's pharmacological profile and potential applications.
https://www.webmd.com/vitamins/ai/ingredientmono-729/wormwood – WebMD provides general information on wormwood, including its uses, potential benefits, and side effects. It notes that wormwood has been traditionally used for various digestive issues and parasitic infections, but also highlights the importance of caution due to potential toxicity, especially with long-term use or high doses.