ProveIt Supplements

Independent, evidence-based supplement analysis.

✓ Not Sponsored

✓ No Paid Reviews

✓ Science-Based

Company

  • About Us
  • Our Methodology
  • Contact
  • Blog
  • Authors

Legal

  • Privacy Policy
  • Terms of Service
  • Medical Disclaimer
  • Affiliate Disclosure

Resources

  • All Categories
  • Ingredient Database
  • Browse Supplements
  • FAQ

© 2025 ProveIt Supplements. All rights reserved.

Medical Disclaimer: The information provided is for educational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen.

Prove It
Browse SupplementsBlogAuthorsAboutMethodologyFAQ
Get Your Personalized Supplement StackSupplement Stack Quiz
Menu
HomeBrowse SupplementsBlogAuthorsAboutMethodologyFAQ
Back

Organic Chinese Skullcap

Also known as: Scutellaria baicalensis, Chinese Skullcap, Huang Qin, Baikal Skullcap

Overview

Scutellaria baicalensis, commonly known as Chinese Skullcap or Huang Qin, is a flowering plant native to Asia and parts of Russia. The dried roots of this plant have been used for centuries in traditional Chinese medicine. It contains bioactive compounds such as baicalein and baicalin, which are known for their anti-inflammatory, antiviral, and anticancer properties. While traditionally used to treat a variety of ailments including infections, inflammation, and even cancer, the scientific evidence supporting these uses is still emerging. It is available in various forms, including capsules, powders, and liquid extracts. Research on Scutellaria baicalensis is ongoing, with studies exploring its potential benefits and safety. However, more rigorous clinical trials are needed to confirm its efficacy and establish standardized dosing guidelines for human use.

Benefits

Scutellaria baicalensis has demonstrated anti-inflammatory and antiviral effects in both animal studies and some human trials. These effects are primarily attributed to its bioactive compounds, baicalein and baicalin. Animal studies suggest potential benefits for reducing stress and improving growth performance, but human data is limited. The plant may be beneficial for individuals with inflammatory conditions or those seeking natural antiviral agents, although the effect sizes and clinical significance are not yet well-quantified in human studies. More research is needed to fully understand the time course of these benefits and to establish the specific conditions and populations that may benefit most from its use.

How it works

Scutellaria baicalensis exerts its effects through the modulation of immune responses and the inhibition of inflammatory pathways, particularly the NF-κB signaling pathway. Its bioactive compounds interact with various body systems, primarily affecting the immune and inflammatory systems. At the molecular level, it targets inflammatory factors such as IL-6 and IL-1β, reducing their activity and thus mitigating inflammation. The absorption and bioavailability of these compounds are not yet well-studied, but the plant's traditional use suggests that its active components are effectively delivered through oral administration.

Side effects

While generally considered safe for short-term use, long-term safety data on Scutellaria baicalensis is lacking. Common side effects include stomach pain, constipation, and vomiting. Less common side effects include potential liver and lung issues, particularly with certain formulations. Drug interactions may occur with diabetes medications and lithium, so caution is advised when combining Scutellaria baicalensis with these drugs. It is contraindicated in pregnancy, breastfeeding, and in individuals with certain medical conditions like bleeding disorders. Special caution should be exercised in children and individuals with liver or spleen issues. It is crucial to consult with a healthcare provider before using Scutellaria baicalensis, especially if you have pre-existing medical conditions or are taking other medications.

Dosage

Due to limited human studies, there is no established minimum effective dose, optimal dosage range, or maximum safe dose for Scutellaria baicalensis. Traditional medicine practices often use it without standardized dosing. It is available in various forms, including capsules, powders, and liquid extracts, but form-specific recommendations are not well-defined. Absorption factors are also not well-studied. Given the lack of established guidelines, it is essential to consult with a healthcare provider to determine an appropriate and safe dosage, considering individual health status and potential interactions with other medications. There are no established required cofactors for its use.

FAQs

Should I consult a healthcare provider before using Scutellaria baicalensis?

Yes, it is crucial to consult a healthcare provider before use, especially if you are taking medications or have pre-existing health conditions, to ensure safety and avoid potential interactions.

Is Scutellaria baicalensis safe during pregnancy and breastfeeding?

No, Scutellaria baicalensis is contraindicated during pregnancy and breastfeeding due to potential risks to the developing fetus or infant. Avoid use during these times.

What are the expected results from using Scutellaria baicalensis?

Results may vary, but some users report reduced inflammation and improved immune response. However, it is not a substitute for medical treatment and should be used with caution and under professional guidance.

Is Scutellaria baicalensis a substitute for conventional medical treatment?

No, Scutellaria baicalensis is not a substitute for conventional medical treatment. It should be used as a complementary therapy and only under the guidance of a healthcare professional.

Research Sources

  • https://pmc.ncbi.nlm.nih.gov/articles/PMC8067852/ – This study found that Scutellaria baicalensis extracts improved growth performance and reduced stress in animals. The research highlights the potential benefits of S. baicalensis in sustainable animal production, suggesting it could be a valuable addition to animal feed.
  • https://pmc.ncbi.nlm.nih.gov/articles/PMC8814103/ – This review discusses the antiviral effects of baicalin and baicalein, compounds found in Scutellaria baicalensis, in the context of COVID-19 treatment. It highlights their ability to modulate immune responses, suggesting potential therapeutic applications, although human efficacy is not yet fully established.
  • https://www.webmd.com/vitamins/ai/ingredientmono-903/baikal-skullcap – WebMD provides a general overview of Baikal Skullcap, noting its traditional uses and potential side effects. It emphasizes the need for more scientific evidence to support its effectiveness in humans and highlights safety concerns associated with certain formulations.
  • https://www.mountsinai.org/health-library/herb/skullcap – Mount Sinai's health library offers information on skullcap, including its traditional uses and potential health benefits. It also mentions potential side effects and interactions, advising caution and consultation with a healthcare provider before use.
  • https://www.healthline.com/nutrition/skullcap – Healthline provides an overview of skullcap, discussing its potential health benefits and uses. The article emphasizes the importance of consulting with a healthcare professional before using skullcap, especially if you have any underlying health conditions or are taking medications.

Supplements Containing Organic Chinese Skullcap

DeTox by Yogi
70

DeTox

Yogi

Score: 70/100
Sinus & Lung Supreme by Gaia Herbs
53

Sinus & Lung Supreme

Gaia Herbs

Score: 53/100
Liver Health by Gaia Herbs
75

Liver Health

Gaia Herbs

Score: 75/100
Resprin by Nu Century Herbs
50

Resprin

Nu Century Herbs

Score: 50/100
Liver Health by Gaia Herbs
58

Liver Health

Gaia Herbs

Score: 58/100
SCIATURNA 18 Herbs, Vitamins & Minerals Including 450 mg ALA Daily Dose by SCIATURNA SINCE NUTURNA® 2009
64

SCIATURNA 18 Herbs, Vitamins & Minerals Including 450 mg ALA Daily Dose

SCIATURNA SINCE NUTURNA® 2009

Score: 64/100
Hemp & Herbs RELIEF by gaia HERBS
78

Hemp & Herbs RELIEF

gaia HERBS

Score: 78/100
Ultra Neuropathy by Life Nutrition™
63

Ultra Neuropathy

Life Nutrition™

Score: 63/100