Organic Coriolus Versicolor Mushroom
Also known as: Coriolus versicolor, Yun Zhi, Turkey Tail
Overview
Coriolus versicolor, commonly known as Turkey Tail, is an edible mushroom found worldwide. It has been used in traditional medicine, particularly in Asian cultures, for centuries. The mushroom contains polysaccharide-K (PSK) and polysaccharopeptide (PSP), which are believed to have immunomodulatory and anticancer properties. As a dietary supplement, Coriolus versicolor is often used to support immune function and as an adjunct therapy in cancer treatment. It is available in various forms, including capsules and powders. Research suggests that Coriolus versicolor may enhance the immune response and improve survival rates in certain cancer patients, especially when used alongside conventional treatments like chemotherapy. While generally considered safe, it's important to use it under medical supervision, particularly for individuals with autoimmune diseases or those undergoing cancer treatment. The quality of available evidence is moderate, with several meta-analyses and systematic reviews supporting its efficacy in cancer treatment.
Benefits
Coriolus versicolor supplementation has been shown to reduce mortality risk in cancer patients, particularly those with breast, gastric, and colorectal cancers. A meta-analysis indicated a 9% absolute reduction in 5-year mortality among these patients. It may also enhance the control rate in non-small cell lung cancer (NSCLC). These benefits are primarily observed in patients undergoing chemotherapy. The effect size is significant, suggesting that for every 11 patients treated, one additional patient may survive over a five-year period. The duration of treatment does not appear to significantly impact survival benefits. These findings suggest that Coriolus versicolor can be a valuable adjunct to conventional cancer therapies.
How it works
Coriolus versicolor is believed to modulate the immune system through its polysaccharide components, primarily PSK and PSP. These polysaccharides enhance immune response by stimulating various immune cells, such as macrophages and T-cells. The exact molecular targets are not well-defined, but it is thought to interact primarily with the immune system, potentially enhancing its function. While the bioavailability of its active components is not extensively studied, they are believed to be absorbed and utilized by the body. This interaction with the immune system may contribute to its observed benefits in cancer treatment and overall immune support.
Side effects
Coriolus versicolor is generally considered safe when used as directed, but comprehensive data on side effects is limited. Common side effects are not well-documented, but typically mild if present. Uncommon and rare side effects are also not well-documented. Potential interactions with immunosuppressive drugs exist, but evidence is limited. Caution is advised in patients with autoimmune diseases due to the potential for immune stimulation. Pregnant or breastfeeding women should consult healthcare providers before use due to limited safety data. It is crucial to use Coriolus versicolor under medical supervision, especially for individuals with pre-existing health conditions or those taking other medications. Long-term safety and interactions with other medications are not fully understood, necessitating caution.
Dosage
The minimum effective dose of Coriolus versicolor is not well-established, but it is typically used in doses of 1-3 grams per day. The optimal dosage range is not clearly defined, but doses up to 3 grams are commonly used. There is no established maximum safe dose, but high doses are generally not recommended without medical supervision. It can be taken at any time, but consistency is recommended. It is available in capsule or powder form; no specific form is recommended over another. Absorption may be influenced by the presence of other nutrients or medications. No specific cofactors are required for its use. It is important to consult with a healthcare provider to determine the appropriate dosage for individual needs and health conditions.
FAQs
Is Coriolus versicolor safe?
It is generally safe but should be used under medical supervision, especially in cancer treatment, due to limited evidence on long-term safety and interactions with other medications.
How should I take Coriolus versicolor?
Consistent daily use is recommended for potential benefits. It can be taken at any time of day, but maintaining a regular schedule is advisable for optimal results.
What are the expected results?
Potential benefits include enhanced immune function and improved survival rates in cancer patients, particularly when used as an adjunct to conventional cancer treatments.
Can Coriolus versicolor replace conventional cancer treatment?
No, it is not a replacement for conventional cancer treatment but may be used as an adjunct to enhance immune function and potentially improve outcomes.
Are there any contraindications?
Caution is advised in patients with autoimmune diseases due to potential immune stimulation. Pregnant or breastfeeding women should consult healthcare providers before use.
Research Sources
- https://pubmed.ncbi.nlm.nih.gov/22185453/ – This meta-analysis examined the efficacy of Coriolus versicolor as an immunotherapeutic agent in cancer treatment. The study found that Coriolus versicolor supplementation resulted in a significant reduction in mortality risk among cancer patients, particularly those with breast, gastric, and colorectal cancers. The findings suggest that Coriolus versicolor can be a valuable adjunct to conventional cancer therapies.
- https://pubmed.ncbi.nlm.nih.gov/31333449/ – This study investigated the effects of Coriolus versicolor and Ganoderma lucidum on cancer outcomes. The systematic review and meta-analysis noted benefits in non-small cell lung cancer (NSCLC), indicating an enhanced control rate. The research suggests that these medicinal mushrooms may offer therapeutic benefits in specific cancer types, warranting further investigation.
- https://www.frontiersin.org/journals/pharmacology/articles/10.3389/fphar.2019.00703/full – This systematic review explores the clinical applications of Coriolus versicolor in cancer treatment. The review highlights the immunomodulatory effects of Coriolus versicolor and its potential to enhance the efficacy of conventional cancer therapies. The findings support the use of Coriolus versicolor as an adjunct treatment to improve outcomes in cancer patients.
- https://www.mskcc.org/cancer-care/integrative-medicine/herbs/coriolus-versicolor – This review from Memorial Sloan Kettering Cancer Center notes the reduced mortality risk associated with the adjuvant use of Coriolus versicolor in cancer patients. The review provides a general overview of the potential benefits of Coriolus versicolor in cancer treatment. It emphasizes the importance of using Coriolus versicolor as part of an integrative approach to cancer care.
- https://www.naturalmedicinejournal.com/journal/efficacy-coriolus-versicolor-yun-zhi-survival-cancer-patients – This article discusses the efficacy of Coriolus versicolor (Yun Zhi) in improving survival rates for cancer patients. It highlights the findings of a meta-analysis that showed a 9% absolute reduction in 5-year mortality among cancer patients who supplemented with Coriolus versicolor. The article underscores the potential of Coriolus versicolor as an adjunct therapy in cancer treatment.