Get Your Personalized Supplement StackSupplement Stack Quiz

Organic Elderberry

Also known as: Sambucus nigra, Black Elderberry, Elderberry

Overview

Black elderberry (*Sambucus nigra*) is a plant native to Europe and North America, widely recognized for its dark purple berries. These berries are rich in anthocyanins, potent antioxidants that contribute to the plant's antiviral and anti-inflammatory properties. Elderberry has been traditionally used as an herbal supplement to treat respiratory infections such as the common cold and influenza. It is available in various forms, including capsules, syrups, lozenges, and teas. The plant's therapeutic effects are primarily attributed to its high concentration of anthocyanins, which may interfere with viral replication and modulate the body's immune response. Research on elderberry is considered moderate, with several clinical trials and meta-analyses supporting its use, though more extensive studies are needed to fully validate its efficacy and safety.

Benefits

Elderberry supplementation has shown potential in reducing the duration and severity of upper respiratory symptoms. Studies suggest that it can significantly alleviate symptoms associated with the common cold and influenza, though the consistency of these findings varies. Some evidence indicates that elderberry may reduce the duration of influenza infections. Additionally, elderberry exhibits anti-inflammatory effects, which may contribute to its overall therapeutic benefits. It may be particularly beneficial for individuals experiencing viral respiratory infections. While some studies report large effect sizes, the overall clinical significance can vary based on the specific condition being treated. Benefits are typically observed within a few days of supplementation.

How it works

Elderberry's antiviral and immunomodulatory effects are primarily attributed to its anthocyanin content. These compounds may interfere with viral replication by binding to viral proteins, preventing the virus from entering host cells. Additionally, anthocyanins can modulate cytokine production, reducing inflammation and enhancing antiviral defenses. Elderberry influences the immune system by potentially reducing inflammation and enhancing antiviral defenses. The bioavailability of anthocyanins from elderberry is generally good, though specific absorption rates can vary depending on individual factors and the form of supplementation.

Side effects

Elderberry is generally considered safe when consumed in recommended doses. Common side effects, though rare, include gastrointestinal upset. Uncommon side effects (1-5%) may include allergic reactions. Severe allergic reactions are rare (less than 1%). Due to its immunomodulatory effects, elderberry may interact with immunosuppressive drugs. Raw or unripe elderberries should be avoided due to the presence of toxic compounds. Pregnant or breastfeeding women should consult healthcare providers before use. It is important to adhere to recommended dosages to minimize the risk of adverse effects. Individuals with autoimmune conditions should exercise caution and consult with a healthcare professional before using elderberry.

Dosage

The minimum effective dose of elderberry extract is typically around 500-1000 mg per day. Optimal dosage ranges are generally between 500-1500 mg per day. The maximum safe dose is not well established, but doses above 1500 mg per day are not commonly recommended. Elderberry is best taken at the onset of symptoms. Common forms include capsules and syrups. Bioavailability may be enhanced with food intake. There are no specifically identified required cofactors. It is important to follow product-specific instructions and consult with a healthcare provider for personalized dosage recommendations.

FAQs

Is elderberry safe to take?

Elderberry is generally safe, but consult a healthcare provider if you have specific health conditions or are taking immunosuppressant medications. Raw or unripe berries are toxic and should be avoided.

When should I take elderberry?

Elderberry is most effective when taken at the onset of symptoms of a cold or flu. Consistent daily use is not typically recommended unless directed by a healthcare professional.

What are the expected results from taking elderberry?

Elderberry may reduce the duration and severity of upper respiratory symptoms, such as cough, congestion, and fever. It does not prevent illness but may alleviate symptoms.

Can elderberry prevent illness?

Elderberry does not prevent illness but may alleviate symptoms. It is often mistakenly believed to prevent colds or flu, but its primary benefit is symptom reduction.

Research Sources

https://pubmed.ncbi.nlm.nih.gov/30670267/ – This meta-analysis of randomized controlled trials found that elderberry supplementation significantly reduced the duration and severity of upper respiratory symptoms. The analysis included data from multiple studies, indicating a large mean effect size for symptom reduction. However, the authors noted the need for more large-scale studies to confirm these findings.
https://pubmed.ncbi.nlm.nih.gov/33827515/ – This systematic review examined the use of elderberry for viral respiratory illnesses and found no evidence that it overstimulates the immune system. The review included five randomized trials and concluded that elderberry does not lead to adverse clinical inflammatory outcomes. The authors conducted a thorough assessment of bias in the included studies, enhancing the reliability of their conclusions.
https://www.tandfonline.com/doi/full/10.1080/09540105.2021.1978941 – This experimental study investigated a high-quality elderberry extract and found antiviral and immunomodulatory effects. The antiviral effects were attributed to the anthocyanins present in the extract. While the study provides valuable insights into the mechanisms of action, it lacks human data, limiting its direct applicability to clinical settings.
https://www.annualreviews.org/content/journals/10.1146/annurev-food-072023-034423 – This review provides a broad overview of the health benefits of berries, including elderberries, highlighting their rich content of bioactive compounds like anthocyanins. It discusses the potential mechanisms through which these compounds exert their health-promoting effects, such as antioxidant and anti-inflammatory activities. The review emphasizes the importance of incorporating berries into a balanced diet for overall health and well-being.
https://magistralbr.caldic.com/storage/product-files/1899087739.pdf – This document likely contains product-specific information about an elderberry extract, possibly including details on its composition, manufacturing process, and recommended uses. It may also provide information on the standardization of the extract to ensure consistent levels of bioactive compounds. While potentially useful, the information should be interpreted in the context of broader scientific literature.