Organic Eldercraft European Elderberry Extract
Also known as: European Elderberry, Black Elderberry, Elderflower, Sambucus, Elder, Sambucus nigra
Overview
European Black Elderberry (*Sambucus nigra*) is a botanical extract derived from a plant native to Europe, North Africa, and Western Asia. The extract is particularly noted for its high levels of bioactive compounds, including anthocyanins, phenolic acids, and flavonoids. Historically, elderberry has been used to alleviate upper respiratory symptoms such as colds and influenza. Its beneficial antioxidant properties, attributed to compounds like cyanidin-3-glucoside and chlorogenic acid, have garnered attention in systematic reviews, which support its efficacy in reducing respiratory symptoms, though further robust clinical trials are necessary for comprehensive validation. As a mature supplement, elderberry offers potential therapeutic benefits in health management, reflecting its traditional and contemporary uses.
Benefits
European elderberry has several evidence-based benefits: 1. **Upper Respiratory Symptoms**: Significant efficacy in alleviating symptoms of colds and influenza; meta-analysis indicates a large effect size from randomized controlled trials. 2. **Antiviral Activity**: In vitro studies demonstrate that elderberry extracts inhibit the replication of SARS-CoV-2, with IC50 values ranging between 1:200 and 1:800. 3. **Antioxidant Potential**: The extract exhibits considerable antioxidant activity due to its rich phenolic content, supporting various health benefits. 4. **Additional Benefits**: Preliminary evidence suggests potential antibacterial and antidiabetic effects; however, these require further clinical investigation. Patients with viral respiratory infections often experience symptom reduction rapidly, though more research is needed to validate its efficacy for COVID-19.
How it works
The antiviral mechanism of elderberry extract involves the inhibition of viral proteases, particularly targeting enzymes such as papain-like protease and 3CLpro, during the replication phase. The antioxidant properties from anthocyanins and phenolic compounds may help reduce inflammation and enhance the immune response, thereby facilitating symptom relief associated with respiratory infections and reinforcing its therapeutic applications.
Side effects
Elderberry is generally safe for most individuals when taken within the recommended dosages; common side effects affecting over 5% of users may include gastrointestinal issues such as nausea and diarrhea. Allergic reactions are rare, occurring in about 1-5% of users with potential symptoms like rashes or itching, while severe reactions are extremely uncommon. Caution is advised for those with autoimmune disorders or those taking immunosuppressive medications due to possible interactions, particularly when considering diabetes treatments. Pregnant or breastfeeding individuals should consult healthcare professionals before use. Special populations, such as children and the elderly, are advised to seek medical advice prior to taking elderberry supplements.
Dosage
For alleviating upper respiratory symptoms, the typical effective dosage of standardized elderberry extract ranges from 500 mg to 1000 mg per day, ensuring a minimum of 3.2% anthocyanin content. Optimal dosages vary, generally from 500 mg to 2000 mg daily, depending on anthocyanin concentration, which may be as high as 14%. Though no formal maximum dose has been established, clinical studies generally do not exceed 2000 mg. For effective therapeutic outcomes, supplementation should begin at the onset of cold or flu symptoms, using preferred forms like liquid, capsule, or tablet, where bioavailability is influenced by extraction methods used.
FAQs
Is elderberry safe?
Yes, generally safe for the general population, but caution is advised for individuals in sensitive categories.
When should I take elderberry?
It is most effective when taken at the onset of cold symptoms or as a preventive during flu seasons.
How quickly can I expect results?
Many users report a reduction in upper respiratory symptoms within a few days of starting supplementation.
Is it effective against COVID-19?
While in vitro studies suggest potential antiviral activity against SARS-CoV-2, there is no clinical data proving its effectiveness for COVID-19.
Research Sources
- https://doi.org/10.1007/s11418-022-00606-5 – This systematic review analyzes the effects of elderberry supplementation on upper respiratory symptoms, finding significant reduction in symptoms related to colds and influenza with robust methodology including randomized controlled trials.
- https://doi.org/10.1016/j.jff.2020.103548 – The study evaluates the antiviral potential of elderberry extract against SARS-CoV-2 in vitro, detailing the IC50 values and the possible mechanisms of action that indicate its therapeutic promise.
- https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4647274/ – This research gives insight into the antioxidant activity of elderberry extracts, highlighting its bioactive compounds and their potential health benefits, including reducing oxidative stress in the body.