Organic Eleuthero
Also known as: Eleutherococcus senticosus, Siberian ginseng, Acanthopanax senticosus
Overview
Eleuthero, scientifically known as *Eleutherococcus senticosus*, is a woody shrub native to Northeast Asia. Often referred to as Siberian ginseng, it is an adaptogen traditionally used in herbal medicine, though it is not related to true ginseng (*Panax ginseng*). Eleuthero contains eleutherosides, acanthosides, phytosterols, and triterpene saponins, which are believed to contribute to its effects. It is primarily used to boost immunity, increase endurance, improve memory, and as an antimicrobial and chemoprotectant. It is also used to treat conditions such as genital herpes and upper respiratory infections (URIs). Research on eleuthero includes in vitro and in vivo studies, with limited human trials, indicating a need for more comprehensive research to validate its benefits. The available evidence is mostly from observational studies, animal studies, and a few human trials.
Benefits
Eleuthero has shown potential benefits in managing genital herpes and upper respiratory infections (URIs). A specific eleuthero extract (Elagen) at 400 mg daily has been shown to decrease the frequency, severity, and duration of herpes simplex virus type II infections. For URIs, a combination of eleuthero and andrographis (Kan Jang) taken within 72 hours of URI onset at 400 mg, three times daily for 4-5 days, significantly decreased symptoms. Secondary benefits include immune system support, with evidence suggesting it may boost immune response and have anti-inflammatory effects. Animal studies also suggest potential improvements in physical performance, memory, and fatigue. A study found that 480 mg per day of eleuthero significantly lowered fasting and post-meal blood sugar levels in subjects with type 2 diabetes.
How it works
Eleuthero is believed to act through several biological pathways, including immune system modulation, anti-inflammatory effects, and antioxidant activities. The active compounds, such as eleutherosides, interact with cellular mechanisms to enhance immune function and reduce inflammation. It may interact with the liver, affecting the metabolism of certain medications, and can influence blood sugar levels and blood clotting. While the bioavailability of eleuthero's active compounds is not well-studied, it is generally considered to be well-tolerated when taken orally. Further research is needed to fully elucidate the mechanisms of action and bioavailability of eleuthero.
Side effects
Eleuthero is generally considered safe when used in standard doses, but comprehensive safety data, especially in special populations like pregnant or breastfeeding women, is lacking. Common side effects include mild drowsiness, anxiety, irritability, melancholy, mastalgia, and uterine bleeding at higher-than-normal doses. Uncommon side effects may include palpitations, tachycardia, and increases in blood pressure. Caution is advised in patients with cardiovascular disease due to potential effects on blood pressure and heart rate. Eleuthero may interact with medications metabolized by the liver and supplements that lower blood sugar or slow blood clotting. It is not recommended during breastfeeding due to a lack of safety data.
Dosage
For URIs, a combination of eleuthero and andrographis (Kan Jang) at 400 mg three times daily is effective, starting within 72 hours of symptom onset. For genital herpes, 400 mg daily of Elagen extract is used. Typically, 400-480 mg per day is used, though more research is needed to establish optimal dosing. The maximum safe dose is not well established, but higher doses may increase the risk of side effects. Oral extracts are commonly used, with specific formulations like Elagen and Kan Jang showing efficacy. Bioavailability is not well studied, but oral administration is the most common method. No specific cofactors are identified in the literature.
FAQs
Is eleuthero safe?
It is generally safe in standard doses but can interact with certain medications and may not be suitable for all populations, especially those with cardiovascular disease or breastfeeding women.
When and how should I take eleuthero?
For URIs, start treatment within 72 hours of symptom onset. For genital herpes, continuous daily use is recommended. Follow specific product instructions for the formulation you are using.
What results can I expect from taking eleuthero?
Potential benefits include reduced symptoms of URIs and genital herpes outbreaks, and potential improvement in immune function and physical performance. Individual results may vary.
Is eleuthero the same as ginseng?
No, it is not true ginseng and has different active compounds and effects compared to *Panax ginseng*. They are distinct herbs with different properties.
Research Sources
- https://medlineplus.gov/druginfo/natural/985.html – MedlinePlus provides general information about eleuthero, including its uses, potential side effects, and interactions. It highlights the importance of consulting healthcare providers before using eleuthero, especially for individuals with pre-existing conditions or those taking medications. The resource emphasizes that more research is needed to confirm many of the purported benefits of eleuthero.
- https://www.heraldopenaccess.us/openaccess/antiviral-activity-and-synergy-of-herba-andrographidis-and-radix-eleutherococci-preparations-against-sars-cov-2-infected-vero-e6-human-primary-embryonic-kidney-epithelial-cells – This study investigates the antiviral activity of *Herba andrographidis* and *Radix eleutherococci* (Eleuthero) against SARS-CoV-2. The research indicates that these herbal preparations exhibit synergistic antiviral effects, suggesting potential therapeutic applications in managing SARS-CoV-2 infections. The study provides insights into the antiviral properties of eleuthero and its potential role in combination therapies.
- https://www.va.gov/WHOLEHEALTHLIBRARY/docs/Adaptogens.pdf – This document from the VA Whole Health Library provides an overview of adaptogens, including eleuthero. It discusses their potential benefits in managing stress and improving overall well-being. The resource emphasizes the importance of using adaptogens as part of a holistic approach to health and wellness, alongside other lifestyle modifications.
- https://www.ncbi.nlm.nih.gov/sites/books/NBK501806/ – This book extract from the National Center for Biotechnology Information (NCBI) provides detailed information on herbal medicine, including eleuthero. It covers various aspects such as its traditional uses, chemical composition, and potential health benefits. The resource serves as a comprehensive reference for understanding the scientific basis and clinical applications of eleuthero.
- https://www.medicalnewstoday.com/articles/319084 – Medical News Today provides an overview of eleuthero, including its potential health benefits and side effects. It highlights the traditional uses of eleuthero and discusses the available scientific evidence supporting its efficacy. The article emphasizes the importance of consulting healthcare professionals before using eleuthero, especially for individuals with underlying health conditions.