ProveIt Supplements

Independent, evidence-based supplement analysis.

✓ Not Sponsored

✓ No Paid Reviews

✓ Science-Based

Company

  • About Us
  • Our Methodology
  • Contact
  • Blog
  • Authors

Legal

  • Privacy Policy
  • Terms of Service
  • Medical Disclaimer
  • Affiliate Disclosure

Resources

  • All Categories
  • Ingredient Database
  • Browse Supplements
  • FAQ

© 2025 ProveIt Supplements. All rights reserved.

Medical Disclaimer: The information provided is for educational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen.

Prove It
Browse SupplementsBlogAuthorsAboutMethodologyFAQ
Get Your Personalized Supplement StackSupplement Stack Quiz
Menu
HomeBrowse SupplementsBlogAuthorsAboutMethodologyFAQ
Back

Organic Helichrysum

Also known as: Immortelle, Everlasting flower, Golden everlasting, Helichrysum italicum

Overview

Helichrysum italicum is a flowering plant native to the Mediterranean region, known for its aromatic yellow flowers. Traditionally used for its health benefits, it is primarily available in forms such as essential oils, extracts, and dietary supplements. This plant contains various bioactive compounds including flavonoids, phenolic acids, and terpenes, responsible for its notable anti-inflammatory, antioxidant, and wound healing properties. Preliminary studies indicate potential therapeutic effects, such as enhanced collagen synthesis and modulation of inflammation. Despite promising benefits, the existing body of research is moderate and predominantly derived from animal studies, necessitating further clinical trials to confirm the efficacy and safety of Helichrysum italicum. Common applications include aromatherapy, topical skincare products, and dietary supplements, highlighting its versatility in herbal medicine.

Benefits

1. Wound Healing: Studies indicate that Helichrysum italicum extracts can significantly accelerate wound healing by enhancing wound contraction and collagen synthesis, as observed in a rat model (Kumar et al., 2008). 2. Anti-Inflammatory Effects: The extracts exhibit anti-inflammatory properties, which may benefit individuals with chronic inflammatory conditions. The strength of evidence for these effects varies, with more reliable outcomes seen in animal studies compared to in vitro investigations (Lopez et al., 2017; Sienkiewicz et al., 2011). 3. Antioxidant Support: Helichrysum italicum's antioxidant properties may protect against oxidative stress, although robust human clinical studies are needed to substantiate these potential benefits.

How it works

The key bioactive compounds in Helichrysum italicum, such as flavonoids and terpenes, function through multiple mechanisms. They inhibit pro-inflammatory cytokines, thus modulating the inflammatory response. Additionally, these compounds possess free radical scavenging abilities, reducing oxidative stress, which plays a crucial role in various diseases. Furthermore, they promote collagen synthesis, which is essential for tissue repair, and may target enzymes like COX-2 that are implicated in inflammatory processes.

Side effects

Helichrysum italicum is generally considered safe for short-term use, especially when applied topically or ingested in moderate amounts. Nevertheless, some users may experience adverse effects, predominantly with topical applications, including skin irritation or allergic reactions in over 5% of users. Less common side effects (1-5%) for oral consumption may include gastrointestinal upset. Rare side effects are reported, although specific incidences lack comprehensive characterization. Caution is advised regarding drug interactions, specifically with anticoagulants and agents metabolized in the liver. Additionally, pregnant or breastfeeding women and individuals allergic to plants in the Asteraceae family are advised against its use due to insufficient safety information.

Dosage

Due to the absence of well-established dosage guidelines from clinical trials, recommended dosages for Helichrysum italicum vary widely. For topical applications, essential oil concentrations typically range from 1-5%. When administered orally, the dosage can differ significantly based on the formulation and intended effect. Topical applications have flexible timing, while oral supplements should adhere to the manufacturer’s instructions or the guidance of a healthcare professional. As no maximum safe dose is defined, users should exercise caution to prevent excessive consumption. For topical applications, lipid-based formulations may enhance bioavailability.

FAQs

Is Helichrysum italicum safe to use?

Yes, it is generally safe for short-term use, but caution is advised for pregnant or breastfeeding women and individuals with certain allergies.

How should I take Helichrysum italicum?

Follow the manufacturer's instructions or consult a healthcare provider for appropriate dosing based on your specific health needs.

What benefits should I expect?

Potential benefits include improved wound healing, reduced inflammation, and antioxidant effects, though individual results may vary.

Are there any misconceptions about this supplement?

It is often mistakenly considered a cure-all; however, it should be part of a balanced health plan.

Research Sources

  • https://www.ncbi.nlm.nih.gov/pubmed/18555102 – This study explored the wound healing effects of Helichrysum italicum extracts, demonstrating significant enhancement in wound contraction and collagen synthesis in a controlled animal model.
  • https://www.sciencedirect.com/science/article/pii/S0378874117300629 – An investigation into the anti-inflammatory properties of Helichrysum italicum revealed its efficacy in reducing inflammatory markers in both in vitro and in vivo settings, highlighting its potential therapeutic applications.
  • https://www.ncbi.nlm.nih.gov/pubmed/21182705 – This research focused on the antioxidant properties of Helichrysum italicum, stressing the importance of clinical trials to fully validate its protective effects against oxidative stress in humans.

Supplements Containing Organic Helichrysum

Relaxed Mind by Yogi
60

Relaxed Mind

Yogi

Score: 60/100
Helichrysum by Hawaii Pharm
70

Helichrysum

Hawaii Pharm

Score: 70/100
Bronchial Wellness by Gaia Herbs
63

Bronchial Wellness

Gaia Herbs

Score: 63/100
Helichrysum by Herbal Terra
73

Helichrysum

Herbal Terra

Score: 73/100
Helichrysum by Herbal Terra
68

Helichrysum

Herbal Terra

Score: 68/100