Organic Passionflower Flowering Vine Extract
Also known as: Passionflower, Maypop, Apricot Vine, *Passiflora incarnata*
Overview
Passionflower, scientifically known as *Passiflora incarnata*, is a flowering vine indigenous to North America and belonging to the Passifloraceae family. It has a long-standing history of traditional use for its calming properties, particularly in managing anxiety and insomnia. The plant is characterized by its rich content of flavonoids, phenolic compounds, and indole alkaloids, which are believed to contribute to its effects. While several clinical studies have been conducted to assess its efficacy, the overall level of research maturity is moderate, indicating a need for more rigorous, systematic investigations into its therapeutic potentials, particularly concerning anxiety disorders and sleep disturbances.
Benefits
Passionflower is primarily recognized for its anxiolytic and sedative effects. Clinical studies suggest that it can significantly reduce anxiety symptoms, demonstrating comparable efficacy to certain benzodiazepines. Preliminary evidence also indicates secondary benefits, including potential anti-inflammatory and antioxidant effects. The strongest evidence supports its use among adults suffering from anxiety disorders, although variability in effect sizes has been noted across studies. It provides immediate sedative effects, with ongoing research needed to fully understand its long-term benefits and mechanisms.
How it works
Passionflower is thought to exert its calming effects through modulation of the GABAergic system. By enhancing GABA levels in the brain, it lowers neuronal excitability, thus promoting relaxation and reducing anxiety. This action positions it as a central nervous system depressant, primarily targeting GABA receptors, which are crucial in regulating neuronal activity and mood.
Side effects
Passionflower is generally considered safe and well-tolerated; however, users may experience common side effects such as dizziness, drowsiness, and nausea. Uncommon effects include confusion and vomiting, while rare side effects can involve increased heart rate and palpitations. Caution is advised in those taking sedatives or monoamine oxidase inhibitors (MAOIs) due to the potential for significant interactions. Special considerations should be taken for pregnant and breastfeeding individuals as there are concerns regarding possible uterine stimulation and insufficient safety data.
Dosage
The recommended dosage of Passionflower varies based on the form of the supplement. For capsules or tablets, 500-1200 mg per day is advised, with the minimum effective dose being around 500 mg. For liquid extracts, a typical dose would be 30-60 drops. For optimal sedative effects, it is recommended to take it before bedtime. Although a maximum safe dose is not well-established, users should practice caution, especially if combining with other supplements or medications.
FAQs
Is Passionflower safe to use?
Generally, Passionflower is well-tolerated, but caution is advised due to potential side effects and interactions with certain medications, particularly sedatives.
How long does it take for Passionflower to work?
The sedative effects of Passionflower can be felt relatively quickly, although more research is needed to determine the time frame for long-term benefits.
Can I take Passionflower during pregnancy?
Pregnant individuals should avoid Passionflower due to potential risks, including uterine stimulation. Consult a healthcare provider before use.
What forms of Passionflower are available?
Passionflower is available in various forms, including capsules, tablets, and liquid extracts, with preparations such as tea also being common.
How does Passionflower compare to other anxiety treatments?
Some studies suggest that Passionflower may be effective in reducing anxiety symptoms and might serve as an alternative to certain benzodiazepines, though results vary.
Research Sources
- https://www.pharmacognosyjournal.net/archives/2024/vol6issue1/PartA/6-1-2-334.pdf – This study evaluates the phytochemical properties and therapeutic effects of Passionflower, highlighting its traditional use for anxiety and sleep disorders.
- https://www.ncbi.nlm.nih.gov/books/NBK548020/ – A comprehensive overview of Passionflower's medicinal uses and effects, particularly its anxiolytic properties supported by varying degrees of evidence.
- https://biointerfaceresearch.com/wp-content/uploads/2021/01/20695837115.1288612900.pdf – The paper explores the interactions of Passionflower with biological systems, assessing its potential benefits and side effects in the context of anxiety treatment.
- https://examine.com/supplements/passionflower/ – This resource provides a distilled analysis of research findings related to Passionflower, summarizing benefits, dosages, and associated risks.
- https://pubmed.ncbi.nlm.nih.gov/33352740/ – This research article discusses a clinical trial assessing Passionflower’s efficacy in treating anxiety, providing evidence for its potential clinical application.