Organic Whole Orange
Also known as: Sweet orange, Citrus aurantium, Bitter orange, Organic whole orange extract, Citrus sinensis
Overview
Organic whole orange extracts are derived from the peels, pulp, and juice of sweet orange (*Citrus sinensis*) and bitter orange (*Citrus aurantium*). These fruits are cultivated without synthetic pesticides and fertilizers, ensuring a natural source of nutrients. Rich in flavonoids such as naringin, hesperidin, and naringenin, these extracts showcase multiple health benefits primarily linked to their antioxidant properties. Available in various forms such as capsules and powders, they are commonly found in dietary supplements designed to enhance general wellness. Research, including both preclinical and clinical trials, supports certain efficacy claims regarding the health benefits of these extracts, although further high-quality human studies are needed to bolster the current evidence base.
Benefits
1. **Lipid Profile Improvement**: Citrus extracts have been shown to reduce total cholesterol, LDL, triglycerides, and VLDL levels while increasing HDL cholesterol. A meta-analysis indicated reductions of -23.4 mg/dL in total cholesterol and -15.6 mg/dL in LDL, demonstrating high evidence quality. 2. **Antioxidant Effects**: Flavonoids in these extracts exhibit significant antioxidant properties that help mitigate oxidative stress, supported by moderate evidence quality. 3. **Weight Management**: Some studies suggest beneficial effects on energy expenditure and fat oxidation, but findings are inconsistent, leading to moderate evidence quality. Improvements in lipid profiles are particularly noted in individuals with dyslipidemia over weeks to months of supplementation.
How it works
Citrus extracts enhance lipid metabolism primarily through their flavonoids, such as naringin and hesperidin, which inhibit enzymes involved in fat synthesis and promote beta-oxidation, leading to improved fat breakdown. Additionally, these compounds boost the body's antioxidant defenses, reducing oxidative stress, which contributes positively to cardiovascular health.
Side effects
Citrus extracts are generally regarded as safe, though gastrointestinal disturbances, including nausea and diarrhea, occur in over 5% of users. Allergic reactions, while rare, can happen. Other infrequent side effects, such as headaches, dizziness, and blood pressure fluctuations, affect about 1-5% of individuals. Severe allergic reactions are extremely rare but should be acknowledged. There are potential drug interactions with anticoagulants, diabetes medications, and stimulants; hence, individuals with heart conditions or hypertension should proceed with caution. Pregnant and breastfeeding women, children, and older adults should also consider dose adjustments and consult healthcare providers.
Dosage
For enhancing lipid profiles, the recommended dosage for citrus extract ranges from 1 to 3 grams daily, standardized for flavonoid content like naringin or hesperidin. A minimum effective dose is approximately 500 mg, and caution is advised not to exceed 3 grams due to risks of adverse effects. Taking these supplements with meals can improve absorption, as hydroalcoholic forms typically have better bioavailability than aqueous preparations. Due to limited data on long-term safety, ongoing evaluations with healthcare providers are recommended.
FAQs
Are citrus extracts safe?
Citrus extracts are generally safe for most people, but they can interact with specific medications. Consultation with a healthcare provider is recommended, especially for individuals with existing health conditions.
When should I take citrus extracts?
Citrus extracts can be taken at any time, but taking them with meals may improve absorption and effectiveness.
How quickly will I see results from citrus extracts?
Improvements in lipid profiles can typically be seen within several weeks to months of consistent use, while weight management results may require longer and often lifestyle changes as well.
Can citrus extracts replace my medications?
No, citrus extracts should not be considered a substitute for prescribed medications but can complement existing treatment under a healthcare provider's guidance.
Supplements Containing Organic Whole Orange
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