Evnol Natural Full Spectrum Tocotrienol Complex
Also known as: alpha-tocotrienol, beta-tocotrienol, gamma-tocotrienol, delta-tocotrienol, EVNol SupraBio, palm tocotrienol complex, full spectrum tocotrienols, Tocotrienols
Overview
Tocotrienols are natural analogues of tocopherols, which belong to the vitamin E family. Found abundantly in palm oil, tocotrienols have gained attention for their potential health benefits, particularly in antioxidant activity, neuroprotection, and cardiovascular health. EVNol SupraBio is a patented full-spectrum tocotrienol complex known for its enhanced bioavailability, allowing for efficient accumulation in the brain, heart, and liver. The research surrounding tocotrienols, especially EVNol, spans over two decades, with various clinical trials pointing to its numerous health benefits, although not all studies yield consistent results.
Benefits
Tocotrienols offer several evidence-supported benefits, most notably in neuroprotection, where research indicates a potential reduction in risks of mild cognitive impairment and Alzheimer’s disease through increased tocotrienol levels in the brain. A significant clinical study noted their effectiveness in reducing White Matter Lesions associated with stroke risk. In cardiovascular health, tocotrienols lower atherogenic apolipoprotein B and lipoprotein(a) levels while exhibiting anti-thrombotic properties. Other documented benefits include decreasing C-reactive protein levels and improving vascular function. Evidence particularly supports elderly populations and those experiencing high oxidative stress as primary beneficiaries of tocotrienol supplementation.
How it works
Tocotrienols work primarily through their potent antioxidant activity, scavenging free radicals and reducing lipid peroxidation, thus protecting cellular structures from oxidative damage. They enhance endothelial function, leading to improved blood flow and reduced cardiovascular risks by increasing nitric oxide synthase expression and decreasing oxidative stress markers. The absorption profile of EVNol SupraBio allows for increased biological availability, facilitating rapid and effective delivery to target organs such as the brain and heart.
Side effects
Overall, tocotrienols are considered safe based on available studies, with no significant adverse effects reported in clinical trials. Common side effects (more than 5%) have not been identified. Among rare reports (less than 1%) and uncommon reports (1-5%), no specific side effects have been tied to tocotrienol supplementation. However, caution is advised for individuals on anticoagulant therapies, given tocotrienols' anti-thrombotic effects. While no explicit contraindications exist, those with bleeding disorders should also seek medical advice before using tocotrienols, and pregnant or breastfeeding individuals should consult healthcare professionals due to lack of adequate safety data.
Dosage
The optimal dosage of tocotrienols typically ranges from 180 mg to 600 mg per day, with specific studies indicating that a daily dose of 400 mg considerably reduces oxidative stress markers like malondialdehyde. While minimum effective doses are still being researched, higher doses have been linked to more substantial health outcomes. Importantly, EVNol SupraBio's formulation enhances absorption without reliance on dietary fat, making consistent daily intake advisable for sustained health benefits. Upper limits and safety thresholds remain to be clearly defined, though clinical reports indicate that up to 600 mg per day is generally safe.
FAQs
Is tocotrienol safe to use?
Generally, tocotrienols are safe, but long-term effects and interactions with other medications still require more investigation.
When is the best time to take tocotrienols?
No specific timing is recommended; consistent daily supplementation is advised to maximize benefits.
What health benefits can I expect from tocotrienol?
You may experience improved cardiovascular health, enhanced neuroprotection, and reduced oxidative stress levels.
What makes EVNol SupraBio different from other tocotrienols?
EVNol SupraBio has unique bioavailability and bioefficiency that enhances its absorption compared to standard tocotrienol formulations.
Research Sources
- https://www.hpcimedia.com/images/PDF/EVNol_Excelvite.pdf – The document provides an overview of EVNol, highlighting its formulation benefits and supported epidemiological studies correlating tocotrienol intake with reduced risks of neurodegenerative diseases and overall cardiovascular health. The safety profile supports its widespread use with no significant adverse effects.
- https://journals.plos.org/plosone/article?id=10.1371%2Fjournal.pone.0255205 – This systematic review and meta-analysis of tocotrienol studies indicates significant findings related to CRP reduction, emphasizing δ-tocotrienols' impact, while noting inconsistencies in results across various studies, underscoring the need for further investigation.
- https://pubmed.ncbi.nlm.nih.gov/10480444/ – Research linked tocotrienols to improved vascular health through mechanisms involving endothelial function, supporting the antioxidant role of tocotrienols and their effectiveness in dietary supplementation to combat oxidative stress.
- https://www.excelvite.com/evnol-palm-tocotrienol-complex-improves-oxidative-stress-induced-vascular-impairments/ – This article discusses the results of animal studies showing that EVNol supplementation improves vascular function, highlighting the potential for tocotrienols to mitigate endothelial impairments related to high-fat diets.
- https://pubmed.ncbi.nlm.nih.gov/34297765/ – A study examining the effects of tocotrienols reveals significant findings regarding neuroprotection and reduction in white matter lesions, supporting the notion of tocotrienols having geographical advantages in brain health.