ProveIt Supplements

Independent, evidence-based supplement analysis.

✓ Not Sponsored

✓ No Paid Reviews

✓ Science-Based

Company

  • About Us
  • Our Methodology
  • Contact
  • Blog
  • Authors

Legal

  • Privacy Policy
  • Terms of Service
  • Medical Disclaimer
  • Affiliate Disclosure

Resources

  • All Categories
  • Ingredient Database
  • Browse Supplements
  • FAQ

© 2025 ProveIt Supplements. All rights reserved.

Medical Disclaimer: The information provided is for educational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen.

Prove It
Browse SupplementsBlogAuthorsAboutMethodologyFAQ
Get Your Personalized Supplement StackSupplement Stack Quiz
Menu
HomeBrowse SupplementsBlogAuthorsAboutMethodologyFAQ
Back

Passion Flower Herb Powder

Also known as: Passiflora incarnata, Passionflower, Passion Vine, Maypop, Passiflora edulis

Overview

Passionflower, scientifically known as *Passiflora incarnata*, is a woody vine native to tropical and subtropical regions. It is commonly used as an herbal supplement to promote relaxation and reduce anxiety. The active compounds are derived from the flowers, leaves, and stems of the plant. Passionflower is primarily used for its calming effects, addressing conditions such as anxiety, insomnia, and stress. Its sedative properties make it a popular choice for individuals seeking natural stress relief. While research on passionflower is considered moderate, with several studies exploring its benefits, more systematic reviews are needed to solidify the evidence base. The quality of available evidence varies, highlighting the need for more rigorous trials to confirm its efficacy and safety.

Benefits

Passionflower is primarily known for reducing anxiety and stress, as well as improving sleep quality. Studies have shown significant improvements in stress resistance and overall quality of life with consistent use. For example, one non-interventional study reported resilience scores increasing from 52.1 to 67.7 points and quality of life scores improving from 47.9 to 75.0 points over a 12-week period. It may also alleviate symptoms of nervous restlessness, such as inner restlessness and sleep disturbances. These benefits are particularly relevant for adults experiencing anxiety or stress-related disorders. The observed effect sizes are moderate to large, indicating clinically significant improvements in stress management and well-being. Benefits are typically noticeable within weeks of consistent use.

How it works

Passionflower's calming effects are attributed to its active compounds, including flavonoids and alkaloids, which interact with the GABA system in the brain. This interaction promotes relaxation by enhancing GABAergic neurotransmission. The primary biological pathways involve the central nervous system, influencing mood and sleep regulation. Specifically, passionflower's compounds target GABA receptors, leading to a reduction in neuronal excitability and a calming effect. While data on the absorption and bioavailability of passionflower extracts are limited, it is generally believed that the active compounds are absorbed through the gastrointestinal tract after oral administration.

Side effects

Passionflower is generally considered safe when used appropriately, but some side effects have been reported. Common side effects, occurring in more than 5% of users, include mild drowsiness or tiredness. Uncommon side effects, affecting 1-5% of users, may include nausea and dizziness. Rare side effects, occurring in less than 1% of users, can include allergic reactions. Passionflower may interact with other medications, particularly sedatives, antidepressants, and blood thinners, potentially enhancing their effects or increasing the risk of adverse reactions. It is contraindicated in pregnancy and breastfeeding due to a lack of safety data. Caution is advised in children and individuals with liver or kidney issues. It's important to consult with a healthcare provider before using passionflower, especially if you have pre-existing medical conditions or are taking other medications.

Dosage

The minimum effective dose of passionflower is typically 200-400 mg of dried extract per day. Optimal dosage ranges for anxiety and stress relief are between 400-800 mg daily. The maximum safe dose is not well established, but doses above 1000 mg are rarely used. For sleep, it is best taken before bedtime, while for anxiety, it can be taken as needed throughout the day. Passionflower is commonly available in capsules or teas. Bioavailability may vary depending on the preparation method. No specific cofactors are required for its effectiveness. It is important to start with a lower dose and gradually increase as needed, while monitoring for any adverse effects.

FAQs

Can passionflower be combined with other calming herbs?

Yes, passionflower can be used in combination with other calming herbs like chamomile. However, it's important to monitor for additive effects and potential interactions.

Is passionflower safe during pregnancy and breastfeeding?

No, passionflower should be avoided during pregnancy and breastfeeding due to a lack of safety data. Consult with a healthcare provider for alternative options.

When is the best time to take passionflower for sleep benefits?

Passionflower is best taken before bedtime to promote sleep. This allows the calming effects to take place as you are trying to fall asleep.

How long does it take to see results from passionflower?

Noticeable improvements in anxiety and sleep quality are typically observed within weeks of consistent use. Individual results may vary.

Is passionflower a substitute for medical treatment for severe anxiety disorders?

No, passionflower is not a substitute for medical treatment for severe anxiety disorders. It can be used as a complementary therapy, but professional medical advice and treatment are essential.

Research Sources

  • https://pmc.ncbi.nlm.nih.gov/articles/PMC7766837/ – This systematic review explores the potential of *Passiflora incarnata* in treating neuropsychiatric disorders. It highlights the herb's ability to reduce stress and anxiety, suggesting it as a promising natural remedy for these conditions. The review consolidates findings from multiple studies, supporting passionflower's role in mental health.
  • https://pubmed.ncbi.nlm.nih.gov/33352740/ – This study investigates the effects of passionflower on anxiety symptoms. The research indicates that passionflower can effectively reduce anxiety levels, making it a valuable option for individuals seeking natural anxiety relief. The findings contribute to the growing body of evidence supporting passionflower's anxiolytic properties.
  • https://examine.com/supplements/passionflower/ – Examine.com provides a comprehensive overview of passionflower, summarizing its benefits and potential side effects. The information aligns with findings from peer-reviewed studies, offering a consolidated resource for understanding passionflower's effects. While not a primary source, it serves as a useful guide for general information.
  • https://karger.com/cmr/article/24/2/83/67984/Improvement-of-Stress-Resistance-and-Quality-of – This non-interventional study found that passionflower extract significantly improved stress resistance and quality of life in adults over a 12-week period. The study reported notable increases in resilience and quality of life scores, demonstrating the potential of passionflower in enhancing overall well-being. These results suggest that passionflower can be an effective supplement for managing stress and improving life quality.
  • https://www.tandfonline.com/doi/full/10.1080/19476337.2025.2504527?src=exp-la – This study provides further insights into the mechanisms and effects of passionflower. The research supports the use of passionflower as a natural remedy for anxiety and stress, highlighting its potential benefits for mental health. The findings contribute to a better understanding of passionflower's therapeutic properties.

Supplements Containing Passion Flower Herb Powder

SleepEasy by Taylor MD Formulations
83

SleepEasy

Taylor MD Formulations

Score: 83/100
Enhanced Sleep Formula by GNC Preventive Nutrition
65

Enhanced Sleep Formula

GNC Preventive Nutrition

Score: 65/100
CLA PM by GNC Total Lean
63

CLA PM

GNC Total Lean

Score: 63/100
Anxiety Control by Metabolic Maintenance
68

Anxiety Control

Metabolic Maintenance

Score: 68/100
Enhanced Sleep Formula by GNC Preventive Nutrition
58

Enhanced Sleep Formula

GNC Preventive Nutrition

Score: 58/100
Nerve Control 911 by PhytAge Labs
75

Nerve Control 911

PhytAge Labs

Score: 75/100
Luna by Avanse Nutraceuticals Lumultra
78

Luna

Avanse Nutraceuticals Lumultra

Score: 78/100
NerveVital by JUVENON®
60

NerveVital

JUVENON®

Score: 60/100
NervaEase by NervaEase
0

NervaEase

NervaEase

Score: 0/100
CalmPro
5 NERVE CALMING FORMULA by CalmPro
5
65

CalmPro 5 NERVE CALMING FORMULA

CalmPro 5

Score: 65/100
NERVO VIVE by Nervo Vive
63

NERVO VIVE

Nervo Vive

Score: 63/100
REJUVAJOINT MAXIMUM STRENGTH by REJUVAJOINT
83

REJUVAJOINT MAXIMUM STRENGTH

REJUVAJOINT

Score: 83/100

Recommended Articles

Top Supplements for Vegan Men in Their 30s

Top Supplements for Vegan Men in Their 30s

Vegan men in their 30s need supplements like Vitamin B12, Omega-3, Iron, Calcium, Vitamin D, and Zinc for optimal health.