Pelargonium sidoides 1X
Also known as: Pelargonium sidoides, African Geranium, Umckaloabo, EPs 7630
Overview
*Pelargonium sidoides*, also known as African Geranium or Umckaloabo, is a plant native to South Africa traditionally used for treating respiratory infections. The primary extract, EPs 7630, is widely studied for its efficacy in acute bronchitis and other respiratory conditions. It is available in liquid and tablet forms. Research indicates it has antimicrobial and immune-modulating properties. The research maturity level is moderate, with several systematic reviews and meta-analyses supporting its use. The quality of available evidence is generally good, though some studies have methodological limitations.
Benefits
*Pelargonium sidoides* (EPs 7630) demonstrates significant benefits in reducing bronchitis symptom scores in both adults and children, with effects often observed within the first few days of treatment. A meta-analysis indicated a significant reduction in symptom scores by day 7. The risk ratio for symptom resolution in adults with acute bronchitis was 0.70 (95% CI 0.6 to 0.82, p<0.0001). Some evidence supports its use for the common cold and sinusitis, though this evidence is less robust. These benefits are supported by multiple RCTs and meta-analyses, indicating a moderate level of research maturity.
How it works
*Pelargonium sidoides* extract has antimicrobial and immune-modulating properties. It enhances interferon-beta synthesis and natural killer cell activity. It affects the respiratory and immune systems by potentially increasing ciliary beat frequency and reducing viral docking proteins. Key molecular components include coumarins and phenolic acids, which may contribute to its antimicrobial effects. Specific data on absorption and bioavailability is limited.
Side effects
*Pelargonium sidoides* is generally well-tolerated with mild side effects. Common side effects include mild gastrointestinal issues and allergic reactions. Epistaxis (nosebleeds) has been reported in some cases. No serious adverse events have been commonly reported. There is limited data on interactions with other medications. There are no well-documented contraindications. Caution is advised in pregnancy and breastfeeding due to a lack of specific studies. Monitor for allergic reactions and discontinue use if any adverse effects occur.
Dosage
The typical recommended dosage is 30 drops of the alcoholic extract three times daily, with a range of 30 to 60 drops three times daily for up to 7 days. It is best taken at the onset of symptoms. Both liquid and tablet forms are effective, though liquid may be preferred for children. While the maximum safe dose is not well-defined, higher doses (60 drops) have been used without serious adverse effects. No specific cofactors are required for absorption.
FAQs
How should I use *Pelargonium sidoides* for best results?
Start treatment early in the course of illness for best results. It is generally safe, but monitor for allergic reactions. Take as directed, ideally at the onset of symptoms. Expect symptom reduction within a few days.
What are the potential side effects and safety precautions?
It is generally safe, but monitor for allergic reactions. Mild gastrointestinal issues and epistaxis (nosebleeds) have been reported in some cases. Caution is advised in pregnancy and breastfeeding due to a lack of specific studies.
What are the expected results and common misconceptions?
It is not a cure for chronic conditions; use for acute respiratory infections. It is effective for reducing symptoms of acute bronchitis and may provide some relief for the common cold and sinusitis.
Research Sources
- https://pubmed.ncbi.nlm.nih.gov/18222667/ – This systematic review and meta-analysis supports the efficacy of *Pelargonium sidoides* in treating acute bronchitis. The review consolidates findings from multiple studies, demonstrating a significant benefit in reducing symptoms associated with acute bronchitis.
- https://www.drugs.com/npp/pelargonium.html – This source provides general information about *Pelargonium sidoides*, including its uses, potential benefits, and side effects. It serves as a broad overview of the supplement and its applications.
- https://pelargonium.org/information-for-healthcare-practitioners/systematic-reviews-meta-analyses/ – This resource offers a compilation of systematic reviews and meta-analyses related to *Pelargonium sidoides*. It provides a summary of research findings for healthcare practitioners, focusing on the effectiveness of the extract in treating respiratory infections.
- https://www.naturalmedicinejournal.com/journal/pelargonium-sidoides-extract-eps-7630 – This article discusses the use of *Pelargonium sidoides* extract (EPs 7630) in treating respiratory tract infections. It highlights the extract's efficacy and safety profile, making it a valuable resource for healthcare professionals.
- https://www.naturalmedicinejournal.com/journal/pelargonium-sidoides-pediatric-bronchitis – This article focuses on the use of *Pelargonium sidoides* in treating pediatric bronchitis. It provides insights into the effectiveness and safety of the extract in children, making it a useful resource for pediatric healthcare providers.
Supplements Containing Pelargonium sidoides 1X
Cold+Flu Elderberry Syrup
Nature's Way
Umcka ColdCare
Nature's Way
Umcka Allergy+Sinus
Nature's Way
Umcka ColdCare Alcohol-Free Drops
Nature's Way
KIDS Cold Relief Syrup
Nature's Way®
Umcka Cold+Flu Elderberry Soothing Syrup
Nature's Way
Cold Relief CHEWABLES
Nature's Way®