Perluxan
Also known as: Phaseolus vulgaris extract, white kidney bean extract, alpha-amylase inhibitor, Perluxan
Overview
Perluxan is a proprietary extract derived from white kidney beans (_Phaseolus vulgaris_). Its primary mechanism is the inhibition of the enzyme alpha-amylase, which plays a crucial role in the digestion of starches. By acting as a carbohydrate absorption inhibitor, Perluxan aims to decrease the absorption of dietary starches, thus supporting weight management and healthy glucose metabolism. The extract is non-stimulant, solvent-free, and sourced from non-GMO plants, making it suitable for various dietary preferences such as vegan and gluten-free. Over the past 15 years, Perluxan has been the focus of several human clinical trials, establishing a moderate body of research. However, the quality varies across studies.
Benefits
Perluxan has been demonstrated to suppress starch digestion and absorption by up to 66%, contributing significantly to weight management when integrated into diet and exercise regimens. Regulatory authorities, including the U.S. FDA and Canada's Natural Health Products Directorate, endorse Perluxan for its weight control and glucose metabolism benefits. Notably, an extensive study revealed that 88% of participating dogs lost weight when administered Perluxan, indicating its effectiveness in both human and animal populations. The clinical relevance of this extract centers on its ability to enhance weight management and improve metabolic responses following carbohydrate-rich meals.
How it works
Perluxan functions by inhibiting the alpha-amylase enzyme, which is essential for the breakdown of starches into simpler sugars. By diminishing the enzymatic activity in the gastrointestinal tract, Perluxan effectively reduces the digestion and absorption of these dietary starches. This localized mechanism does not depend on systemic absorption, allowing for effective management of glucose levels and support for weight control.
Side effects
Perluxan is recognized for its strong safety profile and is self-affirmed as Generally Recognized as Safe (GRAS). While data on adverse effects is not extensive, it is largely well-tolerated, and significant side effects affecting over 5% of users are not documented. Uncommon side effects falling in the 1-5% range and rare side effects under 1% are similarly not reported. Additionally, there are no known drug interactions or contraindications associated with its use, reinforcing its safety across various dietary needs, such as vegan and gluten-free diets.
Dosage
The commonly advised dosage range for Perluxan is between 2000 to 3000 mg per day, which is standardized to provide approximately 3000 Alpha-Amylase Inhibiting Units (AAIU) per gram. To maximize its effectiveness, users should take Perluxan before meals high in starch. While no maximum safe dosage has been established, adherence to the recommended dosage ranges is suggested. Perluxan is available in capsule and powder forms, and as its action is localized in the gastrointestinal tract, systemic absorption concerns do not apply.
FAQs
How does it work?
Perluxan inhibits the alpha-amylase enzyme, reducing starch digestion and absorption.
Is it safe?
Yes, Perluxan has a robust safety profile and is classified as GRAS.
When should I take it?
It is best taken before meals high in starch to enhance its effects.
Are there any side effects?
Perluxan is generally well-tolerated with no significant side effects reported.
How often should I take it?
Use as directed, typically before meals containing starch.
Supplements Containing Perluxan

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ResVitale

Optimized TryptoPure Plus
Life Extension

Extreme Flex
KingFisher Media

Perluxan 375 mg
Bronson Laboratories

Fast Action H.A.
Purity Products

Inflama-Rest
Source Naturals

NeuroOne
Patient One 1 MediNutritionals
Cognitex With Brain Shield
Life Extension

Cognitex With Pregnenolone & Brain Sheild (Gastrodin)
Life Extension