Prolanza
Also known as: Ashwagandha, Indian ginseng, Winter cherry, *Withania somnifera*
Overview
Ashwagandha, scientifically known as *Withania somnifera*, is an adaptogenic herb native to India, Africa, and the Middle East. It is predominantly recognized for its stress-reducing properties and is commonly utilized in dietary supplements. Ashwagandha contains active compounds called withanolides, which contribute to its therapeutic effects. The herb is gaining popularity for applications including stress management, cognitive support, and enhancement of physical performance. Research on ashwagandha shows a moderate level of maturity, with some studies yielding promising results regarding its efficacy; however, there is a need for further rigorous clinical trials to confirm its safety and effectiveness in larger populations.
Benefits
Evidence suggests that ashwagandha may improve stress tolerance and cognitive function. A meta-analysis indicated potential enhancement of VO2max in healthy adults and athletes, although the quality of evidence was deemed low. Secondary benefits of ashwagandha may include improved sleep quality, reduced cortisol levels, and enhanced psychological well-being. These effects are particularly noticeable in populations experiencing high stress or seeking cognitive enhancement. While specific effect sizes for Prolanza remain limited, its sustained-release formulation may provide longer-lasting benefits for users. Regular consumption over weeks to months can lead to significant improvements in stress and overall well-being.
How it works
Ashwagandha exerts its effects primarily by interacting with the hypothalamic-pituitary-adrenal (HPA) axis, leading to a reduction in stress and cortisol levels. This adaptogenic mechanism influences both the nervous and endocrine systems. Moreover, the withanolides present in ashwagandha may interact with GABA receptors and other neurotransmitter systems, contributing to its calming effects. The sustained-release formulation of Prolanza enhances the overall bioavailability of the herb compared to traditional ashwagandha extracts, allowing for more effective absorption and action in the body.
Side effects
Ashwagandha is generally considered safe for most individuals when used appropriately. Common side effects reported (occurring in more than 5% of users) include gastrointestinal upset and drowsiness. Uncommon side effects (1-5%) can include allergic reactions and increased heart rate. While rare side effects (<1%) are not well-documented, caution is advised regarding potential drug interactions. Ashwagandha may interact with sedatives, thyroid medications, and blood thinners, necessitating careful consideration in these cases. Additionally, it is contraindicated for use during pregnancy, breastfeeding, and in those with autoimmune diseases. Special populations, particularly individuals with thyroid disorders, should approach ashwagandha supplementation with caution.
Dosage
The minimum effective dose for ashwagandha is typically around 300-500 mg per day, while optimal dosage for stress management usually falls between 500-1000 mg per day. The maximum safe dose is not thoroughly established, but it is generally recommended to avoid doses exceeding 1000 mg without medical supervision. Prolanza, being a sustained-release formulation, is suggested for once-daily dosing, ideally taken in the morning or before bedtime for optimal effects. Absorption can be improved when taken with food, enhancing the bioavailability of the active compounds.
FAQs
What is Prolanza and how is it different from regular ashwagandha?
Prolanza is a sustained-release formulation of ashwagandha designed for longer-lasting effects compared to standard extracts.
Is it safe to use Prolanza during pregnancy or while breastfeeding?
Prolanza is generally not recommended during pregnancy or breastfeeding due to potential safety concerns.
When should I take Prolanza for best results?
For optimal benefits, Prolanza should be taken consistently, preferably in the morning or before bedtime.
How long does it take to notice effects from Prolanza?
Users may experience reductions in stress and improvements in well-being within a few weeks of consistent use.
Can I take Prolanza with my medication?
Consult your healthcare provider before combining Prolanza with medications, especially sedatives or thyroid medications.
Research Sources
- https://nutraceuticalbusinessreview.com/nutriventia-launches-new-sustained-release-ashwagandha-203705 – This article discusses the launch of Prolanza, highlighting its sustained-release formulation and the potential benefits for stress and cognitive performance.
- https://nutraceuticalbusinessreview.com/prolanza-the-new-age-ashwagandha--203479 – This source reviews Prolanza's pharmacokinetics, demonstrating its higher bioavailability and longer elimination half-life compared to traditional forms of ashwagandha, based on a small sample size study.
- https://www.mdpi.com/2072-6643/12/4/1119 – This systematic review and meta-analysis focuses on the impact of ashwagandha supplementation on VO2max, noting improvements in physical performance among various participant groups. Evidence quality highlighted the need for larger, controlled studies.
