Proprietary Compound
Also known as: Phaseolus vulgaris extract, White bean extract, Kidney bean extract, White kidney bean extract
Overview
Phaseolus vulgaris extract, commonly known as white bean extract, is a dietary supplement derived from the white kidney bean. It is primarily used for weight management due to its ability to inhibit the alpha-amylase enzyme, which is responsible for digesting carbohydrates. By inhibiting this enzyme, the extract reduces the amount of starch that is absorbed by the body, potentially leading to weight loss. The extract is available in various forms, including capsules and tablets, and is often marketed as a natural weight loss aid. Research on Phaseolus vulgaris extract is moderately mature, with several studies suggesting potential benefits, although more robust clinical trials are needed to confirm its efficacy and safety. The quality of available evidence is mixed, with some studies showing significant effects on weight loss, while others report more modest outcomes.
Benefits
Phaseolus vulgaris extract is primarily known for its potential to aid in weight loss and fat mass reduction. Studies suggest that it can lead to statistically significant reductions in body weight and fat, as demonstrated in a meta-analysis. The extract functions by inhibiting alpha-amylase, an enzyme crucial for carbohydrate digestion, thereby reducing starch absorption. This effect may also help reduce overall carbohydrate intake and glucose absorption. While generally applicable to adults seeking weight loss, the clinical significance of these effects can be borderline due to modest effect sizes. Benefits are typically observed over several weeks to months with consistent use. However, it's important to note that Phaseolus vulgaris extract is not a standalone solution and should be used in conjunction with a balanced diet and regular exercise.
How it works
Phaseolus vulgaris extract works primarily by inhibiting the alpha-amylase enzyme, which is responsible for breaking down complex carbohydrates into simpler sugars that can be absorbed by the body. By inhibiting this enzyme, the extract reduces the digestion and absorption of starch in the digestive system. This leads to a decrease in the number of calories absorbed from carbohydrate-rich foods. The extract primarily interacts with the digestive system, specifically targeting the alpha-amylase enzyme. The bioavailability of the active compounds in Phaseolus vulgaris extract is not extensively documented, but its mechanism of action is well-established through enzyme inhibition studies.
Side effects
Phaseolus vulgaris extract is generally considered safe for consumption, but some individuals may experience side effects, primarily gastrointestinal issues. Common side effects, occurring in more than 5% of users, include bloating and gas. Less common and rare side effects are not well-documented. Due to its effects on glucose absorption, Phaseolus vulgaris extract may interact with diabetes medications, potentially affecting blood sugar levels. Caution is advised for individuals with diabetes or those taking medications that affect blood sugar levels; monitoring blood glucose levels is recommended. Pregnant or breastfeeding women should consult healthcare providers before using this supplement. Long-term safety data are limited, so prolonged use should be approached with caution. It is essential to adhere to recommended dosages to minimize the risk of adverse effects.
Dosage
The typical dosage of Phaseolus vulgaris extract ranges from 500 mg to 1500 mg per day, although a minimum effective dose is not well-established. It is best taken before meals to maximize its carbohydrate-inhibiting effects. Capsules or tablets are the most common forms of the supplement. Absorption may be affected by the presence of food in the digestive system, so taking it shortly before eating is advisable. While a maximum safe dose is not well-documented, it is important to adhere to recommended dosages to avoid potential side effects. No specific cofactors are required for its effectiveness. Users should start with a lower dose to assess tolerance and gradually increase as needed.
FAQs
When is the best time to take Phaseolus vulgaris extract?
It is most effective when taken shortly before meals, particularly those high in carbohydrates, to inhibit starch digestion.
Are there any side effects I should be aware of?
Some users may experience gastrointestinal side effects such as bloating or gas. If you have diabetes, monitor your blood sugar levels closely.
How long does it take to see results?
Modest weight loss may be observed over several weeks with consistent use, combined with a balanced diet and exercise.
Is Phaseolus vulgaris extract a substitute for diet and exercise?
No, it is not a magic bullet. It should be used as a supplement to a healthy diet and regular exercise routine.
Can I take this supplement if I have diabetes?
Caution is advised. Monitor your blood sugar levels closely, as the extract may affect glucose absorption and interact with diabetes medications. Consult your healthcare provider before use.
Research Sources
- https://pubmed.ncbi.nlm.nih.gov/33976376/ – This study investigates the impact of white kidney bean extract on weight management. The findings suggest that the extract can contribute to weight loss by inhibiting carbohydrate absorption, but further research is needed to confirm these effects and establish optimal dosages.
- https://pubmed.ncbi.nlm.nih.gov/36142319/ – This research explores the effects of Phaseolus vulgaris extract on body composition. The results indicate a potential for reducing body fat and improving overall body composition, highlighting its role as a supplementary aid in weight management strategies.
- https://bjsm.bmj.com/content/52/6/376 – This article likely discusses the broader context of weight management strategies, potentially referencing the role of supplements like Phaseolus vulgaris extract. It emphasizes the importance of a comprehensive approach, including diet, exercise, and lifestyle modifications, for effective and sustainable weight loss.
- https://www.mdpi.com/1422-0067/23/18/10384 – This paper likely provides a detailed analysis of the molecular mechanisms through which Phaseolus vulgaris extract exerts its effects. It may delve into the specific interactions with alpha-amylase and the subsequent impact on carbohydrate metabolism, offering insights into its potential therapeutic applications.
- https://www.semanticscholar.org/paper/Systematic-Review-and-Meta-Analysis-of-a-Inhibitor-Udani-Tan/ca64570540f29302b694f61a970e10944db10e2a – This systematic review and meta-analysis examines the overall evidence for the efficacy of alpha-amylase inhibitors, including Phaseolus vulgaris extract, in weight management. The findings suggest a statistically significant effect on body weight and fat, but the authors also note the need for more robust clinical trials to confirm these benefits and assess long-term safety.
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