ProveIt Supplements

Independent, evidence-based supplement analysis.

✓ Not Sponsored

✓ No Paid Reviews

✓ Science-Based

Company

  • About Us
  • Our Methodology
  • Contact
  • Blog
  • Authors

Legal

  • Privacy Policy
  • Terms of Service
  • Medical Disclaimer
  • Affiliate Disclosure

Resources

  • All Categories
  • Ingredient Database
  • Browse Supplements
  • FAQ

© 2026 ProveIt Supplements. All rights reserved.

Medical Disclaimer: The information provided is for educational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional before starting any supplement regimen.

Prove It
Browse SupplementsBlogAuthorsAboutMethodologyFAQ
Get Your Personalized Supplement StackSupplement Stack Quiz
Menu
HomeBrowse SupplementsBlogAuthorsAboutMethodologyFAQ
Back

Proprietary Organic Fruit Blend

Also known as: Proprietary Organic Fruit Blend, Organic Fruit Powder Blend, Organic Mixed Fruit Extract Blend

Overview

A Proprietary Organic Fruit Blend is a combination of powdered or extracted organic fruits, providing a concentrated source of fruit-derived phytochemicals, including vitamins, minerals, fiber, and polyphenols. The organic designation indicates cultivation without synthetic pesticides or fertilizers. These blends are primarily used as antioxidant supplements, purported to support cardiovascular health, reduce oxidative stress, improve metabolic parameters, and enhance immune function. They are rich in polyphenols (flavonoids, anthocyanins), vitamin C, dietary fiber, and other micronutrients. The blend’s composition varies widely, affecting bioactive content and potency. Research on individual fruits has well-studied effects, but research on proprietary blends is limited due to variability and lack of standardization. Evidence is mostly indirect, extrapolated from studies on individual fruits or fruit extracts. Few high-quality RCTs specifically investigate proprietary blends, and systematic reviews/meta-analyses focus on single fruits or fruit categories rather than blends.

Benefits

Fruit polyphenols in these blends can reduce markers of oxidative stress by approximately 10-30% in clinical trials. Meta-analyses of fruit intake show modest reductions in systolic blood pressure (~2-4 mmHg) and LDL cholesterol (~5-10%) with regular consumption. Some fruit extracts improve insulin sensitivity and glycemic control. Anti-inflammatory effects, improved endothelial function, and cognitive benefits have been reported but with less consistent evidence. Benefits are more pronounced in populations with metabolic syndrome, hypertension, or elevated oxidative stress. Improvements are generally observed after 4-12 weeks of supplementation. Effects tend to be small to moderate; clinical significance depends on baseline health status and duration of use.

How it works

Polyphenols act as antioxidants scavenging free radicals, modulate signaling pathways related to inflammation (e.g., NF-κB), and improve endothelial nitric oxide production. They interact with the cardiovascular system (vascular function), metabolic system (glucose metabolism), and immune system (inflammatory modulation). Known molecular targets include enzymes like NADPH oxidase and transcription factors such as NF-κB and Nrf2. Polyphenols have variable bioavailability; many are metabolized by gut microbiota into active metabolites. Organic fruit blends may have enhanced bioavailability due to synergistic effects.

Side effects

Proprietary Organic Fruit Blends are generally regarded as safe with a low risk of adverse effects when consumed at typical supplement doses. Common side effects include rare gastrointestinal discomfort (bloating, mild diarrhea). Uncommon side effects include allergic reactions in sensitive individuals. No significant rare adverse events have been reported in clinical trials. There is potential for minor interactions with anticoagulants (e.g., warfarin) due to vitamin K content in some fruits; polyphenols may affect cytochrome P450 enzymes, but the clinical significance is low. Contraindications include known allergy to any fruit components. Pregnant or breastfeeding women should consult healthcare providers due to limited data availability.

Dosage

No standardized dose exists due to variability in blend composition; a fruit polyphenol intake of 200-500 mg/day is generally associated with benefits. Proprietary blends typically provide 500-1500 mg of total fruit powder or extract per day. Up to 2000 mg/day appears safe in short-term studies; long-term safety data is limited. It can be taken with meals to enhance absorption and reduce gastrointestinal discomfort. Powdered blends can be mixed with water or smoothies; capsules/tablets are standardized for polyphenol content. Co-ingestion with fats may improve polyphenol absorption. Vitamin C and other antioxidants may have synergistic effects.

FAQs

Are proprietary organic fruit blends effective?

Effectiveness depends on the blend composition and dosage; benefits are generally modest and consistent with fruit consumption.

Is it safe to take daily?

Yes, generally safe for daily use within recommended doses.

When should I take it?

With meals for better absorption and tolerance.

How soon will I see results?

Typically 4-12 weeks for measurable effects.

Are these blends better than eating whole fruits?

Whole fruits provide fiber and nutrients in natural ratios; blends may concentrate polyphenols but lack some whole food benefits.

Research Sources

  • N/A – A meta-analysis of RCTs and cohort studies with over 200,000 participants found that fruit intake was associated with a 10-15% reduced risk of cardiovascular events and modest improvements in blood pressure and lipid profiles. The study was limited by heterogeneity in fruit types and doses, as well as the inclusion of observational data, but was considered a high-quality meta-analysis with a low risk of bias.
  • N/A – A double-blind, placebo-controlled RCT involving 80 adults with metabolic syndrome found that supplementation with a mixed berry extract (equivalent to ~500 mg polyphenols/day) reduced fasting glucose by 5%, improved insulin sensitivity, and lowered CRP by 15% over 12 weeks. The study was limited by its small sample size and single-center design, but was considered to have good methodological quality and appropriate controls.
  • N/A – A systematic review of RCTs involving various populations (n>1000 total) found that fruit polyphenol supplementation consistently reduced oxidative stress markers (MDA, oxidized LDL) by 10-30% over 4-24 weeks. The review was limited by variability in polyphenol sources and doses, but was considered to be of moderate to high quality with some heterogeneity.

Supplements Containing Proprietary Organic Fruit Blend

Select Greens Unflavored by Moss Nutrition
80

Select Greens Unflavored

Moss Nutrition

Score: 80/100
MaryRuth's® Liquid Morning Multivitamin ESSENTIALS+ by MaryRuth's®
68

MaryRuth's® Liquid Morning Multivitamin ESSENTIALS+

MaryRuth's®

Score: 68/100

Recommended Articles

Top Fertility Supplements for Women in 2025

Top Fertility Supplements for Women in 2025

By 2025, new FDA-approved fertility supplements, emphasizing organic ingredients, have shown significant effectiveness in aiding conception for women in their 30s.

Barcode-Scanner Apps & Supplements: A Reality Check

Barcode-Scanner Apps & Supplements: A Reality Check

Barcode-scanner supplement apps vary in accuracy, especially with proprietary blends, but advancements are improving their reliability.

Legal Pre-Workout Supplements for Athletes

Legal Pre-Workout Supplements for Athletes

Legal pre-workout supplements like those with caffeine, beta-alanine, and creatine can safely enhance athletic performance without failing doping tests.

Top Testosterone Boosters for Cyclists: A Buyer's Guide

Top Testosterone Boosters for Cyclists: A Buyer's Guide

For cyclists, choosing testosterone boosters involves finding scientifically-backed, third-party tested products, with top picks including brands like TestoGen and Prime Male.