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Proprietary Testosterone Matrix

Also known as: Withania somnifera, Ashwagandha, Indian ginseng, Winter cherry, KSM-66® Ashwagandha

Overview

KSM-66® Ashwagandha is a proprietary extract of *Withania somnifera*, a plant native to India, Africa, and the Middle East, known for its adaptogenic qualities. Traditionally used in Ayurvedic medicine, ashwagandha supports various health aspects including stress reduction, cognitive enhancement, and potentially testosterone production. KSM-66® is a full-spectrum extract distinguished by its high bioavailability, capturing the complete profile of bioactive compounds found in ashwagandha. While research indicates moderate efficacy in improving stress management and physical performance, results can vary significantly across different studies. Overall, KSM-66® serves as a herbal supplement aimed at promoting overall male health and hormonal balance.

Benefits

Research supports several benefits of KSM-66® Ashwagandha, including stress reduction and improved muscle strength. A randomized controlled trial demonstrated that supplementation led to an 18.5% increase in muscle strength compared to placebo, highlighting its potential in physical performance enhancement. Additional studies indicate that it can also enhance cognitive function, although findings regarding its effects on testosterone levels are more varied. The strongest evidence is associated with stress and anxiety reduction, particularly beneficial for healthy adults and athletes. Most benefits are typically observed within a few weeks of consistent supplementation.

How it works

Ashwagandha functions primarily as an adaptogen, modulating the body's stress response by influencing the hypothalamic-pituitary-adrenal (HPA) axis. This interaction helps lower cortisol levels, which is pivotal in stress management. Additionally, ashwagandha may indirectly support testosterone production by balancing various hormonal pathways in the body. Its active constituents interact with neurotransmitter systems and exert antioxidant effects, contributing to its overall health benefits.

Side effects

KSM-66® Ashwagandha is generally well-tolerated with a favorable safety profile. The most common side effects reported (>5% incidence) include gastrointestinal upset, which is relatively rare. Less common side effects (1-5% incidence) can encompass allergic reactions. Serious adverse effects are not well-documented, occurring in fewer than 1% of users. Caution is recommended when using ashwagandha alongside sedatives or thyroid medications due to potential interactions. Pregnant or breastfeeding women should avoid ashwagandha due to the lack of comprehensive safety data. Additionally, individuals with autoimmune diseases should consult a healthcare professional before use.

Dosage

The minimum effective dosage range for KSM-66® Ashwagandha is generally between 300-500 mg per day. For optimal benefits, particularly for stress reduction and physical performance, doses of 500-1000 mg per day are recommended. While there isn't a well-studied maximum safe dose, doses beyond 1000 mg should be approached cautiously. For best results, it’s suggested to take ashwagandha with meals to mitigate gastrointestinal side effects. Capsules or tablets are the most common forms available, and the high bioavailability associated with KSM-66® enhances absorption. There are no specific cofactors required for its activity.

FAQs

Can ashwagandha help boost testosterone levels?

While ashwagandha may support hormonal balance, its effects on testosterone are less consistent and not fully established.

Is ashwagandha safe to take with other medications?

Generally safe, but consult a healthcare provider if you're taking sedatives or thyroid medications.

How long does it take to see the effects of ashwagandha?

Benefits can typically be observed within a few weeks of consistent supplementation.

Should pregnant or breastfeeding women take ashwagandha?

No, ashwagandha is not recommended for pregnant or breastfeeding women due to insufficient safety data.

Can I take ashwagandha every day?

Yes, ashwagandha can be taken daily, ideally at recommended dosages for optimal results.

Research Sources

https://journals.physiology.org/doi/full/10.1152/ajpendo.2001.281.6.E1172 – This study discusses the physiological impacts of various adaptogenic substances including ashwagandha. It affirms the herb's role in reducing cortisol and supporting stress management, with implications for overall wellness.
https://pubmed.ncbi.nlm.nih.gov/30770069/ – This randomized controlled trial involving healthy men showed that ashwagandha improved muscle strength and reduced body fat percentage over an 8-week period, providing moderate evidence of its efficacy in enhancing physical performance.
https://pubmed.ncbi.nlm.nih.gov/37804846/ – A systematic review of ashwagandha studies found consistent reductions in stress and anxiety across both animal and human trials, demonstrating its adaptogenic qualities and overall safety.
https://pubmed.ncbi.nlm.nih.gov/32358510/ – This meta-analysis summarizes the positive effects of ashwagandha on cognitive function and stress levels, indicating significant benefits across multiple studies with moderate to high quality of evidence.
https://cytomatrix.ca/products/testosterone-matrix/ – The product page outlines the benefits and features of the Proprietary Testosterone Matrix, primarily focusing on its key ingredient, KSM-66® Ashwagandha, and its role in supporting testosterone production and overall male health.